What Is PQQ
PQQ powder, scientifically known as pyrroloquinoline quinone, also known as methoxatin, is an essential nutrient the body must obtain from food. It is a coenzyme of oxidoreductase, and because of its unique o-benzoquinone structure, it has many different physiological characteristics from other coenzymes, so it has various physiological functions. Pyrroloquinoline quinone is a new prosthetic group that treats heart disease and neurological diseases, protects the liver, and maintains mitochondrial function. Pyrroloquinoline quinones are widely found in prokaryotes, plants, and mammals. Located in various everyday foods, including foods of plant and animal origin, such as fruits, vegetables, grains, and beverages. Exist in soil and are also produced by soil bacteria. In addition, some bacteria in fermented foods and drinks produce PQQ. Present in all body tissues, concentrated in breast milk, is a growth factor necessary for development. It is not only the prosthetic group of many enzymes responsible for the function of transferring electrons, protons, and chemical groups in enzymatic reactions. It can also stimulate the growth of microorganisms and plant pollen germination and promote plant growth.
PQQ is a volatile and rare active substance, known as the king of immunity by the global biomedical community and the most potent antioxidant substance in history. Experiments have proved that the speed and thoroughness of PQQ in killing bad cells have reached unprecedented heights, and it is even more impressive in improving immunity. It is the most potent biologically active substance discovered by humans so far. It is a high-tech anti-aging ingredient that can enhance the quantity and quality of mitochondria, promote the synthesis of growth factors, and effectively strengthen the three major systems of the human body. It is currently the only antioxidant on the market that can use in the medical field. It can eliminate heart disease and other problems caused by free radicals. Continued use can also inhibit the transfer of diseased cells and enhance the body's resistance and anti-inflammatory effects. Its raw materials contain anthocyanins and lps, which are relatively safe. So it is anti-aging and a good thing that can improve your physical and mental health and increase your vitality.
The discovery of PQQ is a significant event in the history of kinase research. It recognized a new prosthetic group, which meant a new branch appeared in enzymology. There are substantial research results on PQQ at home and abroad. It has the potential to develop new health drugs. The US and the EU have listed it as a high-safety dietary supplement, and there will be more and more demand in the international market. Xi'an Sonwu is a manufacturer that provides raw materials for production. If you are looking for PQQ, you can contact Xi'an Sonwu. When you receive the product, you will be amazed at the quality of pure PQQ.
Certificate Of Analysis
Item | Specification | Results |
Appearance | Dark red powder,oddrless | Conforms |
Solubility | DMSO (Slightly), Methanol (Slightly) | Conforms |
PH | 6.0~7.5 | 6.9 |
Solution clarity and color | Solution should be clear and colorless | Conforms |
Related substancss | 5CMP0.3% Simple impurity Total other impurty | 0.01% 0.03% 0.10% |
Chlorde | 0.05% | Conforms |
Ammonium | 0.05% | Conforms |
Fe | 0.01% | Conforms |
Phosphate | 0.1% | Conforms |
Loss on drying | ≤6.0% | 1.3% |
Heavy metals | 0.002% | Conforms |
Arsenide | 0.0001% | Negative |
Bacterial Endoxins | 0.3EUU/mg | Negative |
Micobial Limit | Conforms | Conforms |
Assay | ≥99.0% | 99.8% |
Conclusion | Conform with specification |
Where To Buy PQQ
Xi'an Sonwu Biotech Co., Ltd. has rich experience in the global trade and healthcare industry. Xi'an Sonwu strictly controls the color, shape, smell, and other aspects to ensure the production of high-quality products. Xi'an Sonwu strives to do an excellent job in every production link, which means that every step, from the selection of raw materials to the final presentation of the product, is strictly controlled. Xi'an Sonwu pursues to serve every customer well and meet the needs of every customer. Based on these, customers have given good feedback on products and services. So if you need PQQ, please find Xi'an Sonwu Biotech Co., Ltd.
Xi'an Sonwu ultimately makes specific products quality and provides the sample. Here is the quantity.
Form | Sample Amount | MOQ |
Powder | 5g | 10g |
Bulk capsules | 200 capsule | 200 capsule |
Bottle capsules | 5 bottles | 5 bottle |
Customers' Good Comment
OEM Service
Xi'an Sonwu not only can supply high-quality powder but also capsules.
So any customers could customize the capsules they want. And Xi'an Sonwu can provide the following items.
1. Customized capsules shells (size, color, material)
2. Customized bottles(size, color, material, style)
3. Customized packaging(vacuum foil packaging, box, drum)
4. Customized label(paint film, matte film, optical mask)
Pyrroloquinoline Quinone Benefits
1. Extensive nutritional functions
PQQ powder has a wide range of nutritional and nourishing functions, summarize from three aspects: microorganisms, plants, and animals.
(1) PQQ promotes microbial growth
There are two ways for PQQ to promote the growth of microorganisms: the first is to shorten the lagging period of the bacteria, which plays the same role as the growth factor, accelerates the growth rate of the bacteria in a concentration-dependent manner, and increases the cell yield of the bacteria; the second only shortens the lagging period of the bacteria, Does not accelerate the growth rate of bacterial cells.
(2) PQQ promotes plant growth
In 1988, scientists reported that PQQ could stimulate lily pollen germination. Subsequent studies have found that PQQ can stimulate pollen germination in tea, musk lily, camellia oleifera, and tulip. The researchers believe that the mode of PQQ to stimulate pollen germination is roughly the same as that of stimulating microbial growth, promoting plant growth by shortening the growth stagnation period.
Domestic scholars have found that PQQ can promote tobacco seed germination and increase lipase activity and seed respiration rate. PQQ can also promote plant growth by promoting the synthesis of auxin and cytokinin, and promoting gene regulation at the molecular level, thereby improving the metabolism of plant cells. Spraying PQQ at the booting stage and vigorous growth and metabolism stage of winter wheat flower degeneration peak can increase the chlorophyll content in the leaves, accelerate the photosynthesis of plants, increase the activity of alanine aminotransferase and nitrate reductase, thereby regulating the physiological, metabolic function of the plant, which is beneficial to Improve the nutrient supply of the plant, reduce the abortion of florets in the ears, and increase the ear setting rate of wheat ears.
(3) PQQ affects the growth and reproduction of animals
PQQ is an essential nutritional factor for animals, even if it cannot be produced endogenously.
Lack of PQQ causes poor growth and reduced fertility in mice. Females littered half as many litters as females whose diets included PQQ, and half of the offspring of PQQ-deficient females did not survive the weaning period (4 weeks). The lack of PQQ in pregnant or newborn mice will cause the content of lysyl oxidase in the skin to be only 10% to 30% of the average skin value, the solubility of collagen will double, and the skin will become dry and easy to fall off. For the human body, only human cell experiments have proved that PQQ stimulates the growth of human fibroblasts, and the stimulating effect is dose-related. When the concentration of PQQ is 0.003~0.03/L, it can effectively promote the DNA synthesis, replication, and cell division of fibroblasts tested in vitro; when the attention of PQQ is >300μ/L, it will inhibit DNA synthesis and cause cell death and degradation. Therefore, in the human body, PQQ and glycine combine to form oxazole as a reserve, and when the body needs PQQ, the two dissociate.
2. Antioxidant function
The production and removal of various free radicals in organisms should be in a dynamic balance. That is, the free radicals in the body should always maintain a certain level. Too much or too little free radicals are not suitable for the body. When it is too much, it will promote the body's aging and cause various diseases, including cancer, heart disease, etc.; when it is too small, it will also affect health and even hinder normal metabolism or induce another type of disease. PQQ is a prosthetic group of oxidoreductase, which participates in redox reactions in organisms, can effectively remove free radicals in the body, reduce the damage caused by free radicals to the human body, protect body tissues, and reduce various diseases caused by body damage.
3. PQQ and various diseases research evidence
Due to its nutritional and antioxidant properties, PQQ has shown certain "benefits" in different laboratory disease models.
(1) Protect the heart from oxidative damage
PQQ can scavenge reactive oxygen species produced by hypoxia-reperfusion and significantly reduce the release of lactate dehydrogenase in the heart. Under the catalysis of flavin reductase, its catalyzed product can lessen the peroxidation state of hemoglobin and eliminate the myocardial injury caused by hypoxia-reperfusion. Studies have shown that using PQQ can protect the heart of ischemia-reperfusion mice, the myocardial infarction size in mice is reduced, left ventricular pressure is increased, and ventricular fibrillation is diminished. The level of malondialdehyde in myocardial tissue is reduced. PQQ can also inhibit hydrogen peroxide-induced ROS generation in rat cardiomyocytes and reduce mitochondrial membrane potential, thereby reducing oxidative stress, inhibiting the inactivation of mitochondrial function, and protecting rat cardiomyocytes.
(2) Promote nerve growth and protect the nervous system
The earliest discovered and most thorough study of neurotrophic factors is a nerve growth factor. It has dual biological functions of neuron nutrition and neuroprotection and is specific to central and peripheral neurons' growth, development, differentiation, regeneration, and biological processes. Expression plays an important regulatory role. Experiments have shown that in vitro, PQQ can stimulate L-M and Schwann cells to produce nerve growth factors. The growth factor is the hormone of human growth, which enables the growth of organisms, promotes the development of human cells, increases cell density, and a small amount of PQQ can improve the metabolic capacity and growth function of biological tissues.
(3) Prevent acetaldehyde poisoning
Acetaldehyde is an intermediate metabolite of alcohol in animals, which is toxic. Many people have mutations in the acetaldehyde dehydrogenase gene and incomplete function, resulting in mild acetaldehyde poisoning reactions. Rodent experiments have found that PQQ helps metabolize acetaldehyde. The test found that after using PQQ, the ethanol concentration in the blood and liver of the treatment group showed no significant difference from the control group. Still, the acetaldehyde concentration of the former was much lower than that of the latter. Replacing PQQ with other quinone derivatives, such as coenzyme Q10, has a similar effect.
(4) Prevention and treatment of liver damage
PQQ can significantly reduce serum bilirubin and alanine aminotransferase levels, maintain normal liver function, regulate liver damage, and has an excellent curative effect on liver diseases.
(5) Comprehensively improve human immune function
As an essential factor for human development, PQQ can stimulate the growth of human cells, primarily activating human B cells and T cells to produce antibodies and improve the immune function of the human body. PQQ is the most potent biologically active substance discovered by humans so far.
(6) Promotes absorption of amino acids
PQQ is a prosthetic group that participates in the electron transfer of the respiratory chain and can promote the absorption of amino acids through the action of glucose in the human body. Amino acids are the primary raw materials for the composition of cell fluid and synthetic protein peptides and are essential components of all biologically active substances.
(7) Prevention of Alzheimer's disease
The particular biological activity and physiological function of PQQ are also manifested in the ability to repair nerve fibers, activate neurons, and activate dormant nerve cells, which can effectively prevent Alzheimer's disease and improve memory, thereby enhancing intelligence.
PQQ Supplement Side Effects
PQQ is a pyrroloquinoline quinone, which belongs to a healthcare product. Generally, it does not produce noticeable side effects on the human body. Still, if it is supplemented in excess, it may increase the burden on the gastrointestinal tract, liver, and kidneys.
Usually, if there is a lack of PQQ in the body, you can take a small amount of PQQ and other health products. Taking a small amount or lacking body generally does not cause side effects. However, if there is no deficiency, blindly supplementing a large amount of PQQ may increase the burden on the gastrointestinal tract because it will be digested and absorbed through the gastrointestinal tract, so it may cause nausea, vomiting, or abdominal pain, bloating, and other symptoms. In addition, the metabolism of drugs needs to go through the liver and kidneys. PQQ's pharmacological effects and pharmacokinetics still need to be clarified as a health product. Overdose may cause damage to liver and kidney functions, causing discomfort in the liver area and abnormal urine output.
Suppose there is a lack of nutrients in the body. In that case, targeted supplementation is generally required, and excessive supplementation is usually not recommended, especially some health products, so as not to hurt the body. In supplementing certain nutrients or taking health care products, if there are abnormal symptoms, such as abnormalities in the digestive tract, it is necessary to stop taking them in time to prevent the symptoms from aggravating.
Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.
Certificate
Packaging
Logistics
Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
FAQ
The everyday PQQ powder supplement products currently on the market are also mainly aimed at brain health, energy supplement, sleep aid, oral beauty, pregnancy aid, etc., and are often used in conjunction with various raw materials such as MNM, coenzyme Q10, ginkgo leaf extract, and PS. Mainly focus on the international market. In the United States, PQQ can be used as a raw material for food, such as energy, sports, electrolyte, and bottled water. In the European Union and Canada, it can be used as a dietary supplement or natural health food.
If you are interested in PQQ, you can contact Xi'an Sonwu. Click the email to get in touch with the best PQQ price and high-quality manufacturer.
Email:sales@sonwu.com
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