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5-Mthoxytryptamine Powder

5-Mthoxytryptamine Powder

Appearance: White to yellowish brown crystalline powder
Specification: 99% min
CAS: 608-07-1
Molecular Formula: C11H14N2O
Molecular Weight: 193.2601
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 5-mthoxytryptamine powder in China. We warmly welcome yuo to wholesale bulk 5-mthoxytryptamine powder for sale here from our factory. Quality products and reasonable price are available.

 

Mexamine Powder

5-mthoxytryptamine powder (Mexamine, Methoxytryptamine, O-methylserotonin, 5-MT) is an organic compound used as a pharmaceutical intermediate, mainly for synthesizing melatonin. Its protective role against UV-B has been studied in human keratinocytes. Mexamine can be a biological synthesis through melatonin dehydration in the pineal body and can naturally occur at low levels. It is a tryptamine derivative closely related to the neurotransmitters melatonin and serotonin.

Mxamine will have no affinity for 5-HT3 receptors but will have a full-act agonist at 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. The following is the measurement data of Mxamine on HT receptors:

HT receptors

Ki


5-HT1

5-HT1B

35 nM

5-HT1D

7.3 nM

5-HT1E

3151 nM

5-HT1F

1166 nM


5-HT2

5-HT2A

295 nM

5-HT2B

16.4 nM

5-HT2C

52.48 nM

5-HT3

5-HT3

/

5-HT4

5-HT4

501.18 nM

5-HT6

5-HT6

69.18 nM

5-HT7

5-HT7

5.01 nM

Xi'an Sonwu is a manufacturer that provides raw materials for production. If you are looking for tryptamine products, you can contact Xi'an Sonwu. When you receive the product, you will be amazed by the quality of pure 5-mthoxytryptamine.

5-Mthoxytryptamine powder structure


Certificate Of Analysis

ANALYSIS

SPECIFICATION

RUSULT

Assay

≥98.0%

99.5%

Characters

White to yellowish brown crystalline powder

Conform

Particl size

100 pass 80mesh

Conform

Melting point

245-250 °C (dec.)(lit.)

248.53C

Arsenic

NMT 2 ppm

Conform

Loss on drying

NMT 2 ppm

Conform

Solubility

Chloroform (Slightly), Methanol (Slightly)

Conform

Total plate count

≤500cfu/g

Conform

Salmonella

Negative

Negative

E.Coli

Negative

Negative

Pseudomonas

Negative

Negative

Staphylococcus

Negative

Negative

Melamine

Negative

Negative

Conclusion

Conforms with enterprise standard


Mexamine Powder For Sale

Xi'an Sonwu Biotech Co., Ltd. has rich experience in the global trade and healthcare industry. Xi'an Sonwu strictly controls the color, shape, smell, and other aspects to ensure the production of high-quality products. Xi'an Sonwu strives to do an excellent job in every production link, which means that every step, from the selection of raw materials to the final presentation of the product, is strictly controlled. Xi'an Sonwu pursues to serve every customer well and meet the needs of every customer. Based on these, customers have given good feedback on products and services. So if you need 5-methoxy-tryptamine, please find Xi'an Sonwu Biotech Co., Ltd.

Xi'an Sonwu ultimately makes certain product quality and provides the sample. Here is the quantity.

Form

Sample Amount

MOQ

Powder

1000g

1000g


Customers' Good Comment

Customers' Good Comment2


Does 5-Methoxytryptamine Affect Behavior In Nonhuman Primates

5-methoxytryptamine powder is a kind of tryptamine substance, and like tryptamine products, it is a kind of structural analog of hallucinogens. It is a substance found in the brain of mammals. So does it affect the behavior of nonhuman primates? In response to this doubt, some scientists conducted some experiments. The first study looked at dose-dependent behavioral changes induced by seven higher doses of Mexamine in four macaques.

At higher doses of 10-20 mg/kg, bob-tailed macaques would have two abnormal behaviors: body trembling and limb twitching. The second study was at 10 mg/kg/day. Taking it for five consecutive days, the macaques developed tolerance to body shaking and limb twitching. Body trembling and limb twitching, two behaviors typical of hallucinogenic compounds-induced behaviors, after five days suggest that Mexamine may have hallucinogenic properties in nonhuman primates. However, the dose and effect of the experiment are relatively weak, and the impact of Mexamine at high doses will be more obvious.

5-Mthoxytryptamine powder for bob-tailed macaques


5-Methoxytryptamine Pruritus

Pruritus is an unpleasant feeling that can cause the desire to scratch. It is a response mechanism for self-protection in the body's physiological state, just like pain and other sensations. There are many traditional medicines for treating pruritus, among which antihistamines are the most widely used. And 5-methoxytryptamine, which belongs to tryptamine products, also has antiviral and anti-itching effects.

Experiments were conducted on healthy Kunming mice of half male and half female, 8-12 weeks old, and 18-22 g. The animals were divided into five groups: blank group, model group, positive control group (PD176252 group), and administration group. The administration group was divided into 17 groups, and each group used six mice. Experimental verification proves that 5-Methoxytryptamine has an inhibitory effect on viruses and itching.


5-Methoxytryptamine Application

As an agonist, 5-methoxytryptamine has been used to study the pharmacological effects of 5-HT1 receptors. Reactants for the preparation of:

1-indolyl substituted β-carboline alkaloids and their derivatives

melatonin

5-HT4 receptor ligand

Inhibitors of sortase A and isocitrate lyase

Therapeutic agents for the treatment of ischemia/reperfusion (I/R) injury

Aurora and epidermal growth factor receptor kinase inhibitors

Manzamine analogs to control neuroinflammation and brain infection

Inhibitors of pro-inflammatory cytokines

Tacrine-melatonin hybrid as a multifunctional drug for Alzheimer's disease

5-Mthoxytryptamine powder Application

The best known are 1-indolyl substituted β-carboline alkaloids and their derivatives and melanin. 1-Indolyl-substituted β-carboline alkaloids and their products, in addition to being benzodiazepine receptor ligands, also have anti-platelet aggregation, anti-bad cell, anti-virus, antibacterial, anti-parasitic, anti-oxidation, inhibitory Phosphodiesterase, and many other biological activities. For example, Chuanxiongdole, which has a specific curative effect on coronary heart disease, Lavendamycin, which has an antibacterial, anti-bad cell, and HIV reverse transcriptase inhibitory effects, Harmalo, which has anti-oxidative effects, and calamine, which has anti-bad cell activity. Many compounds in eudistomin marine alkaloids with β-carboline structures have suitable antiviral, antibacterial, and anti-destructive cell activities, so they have attracted widespread attention.

The chemical name of melatonin is N2 acetyl 252 methoxytryptamine. Dermatologists first extracted it from the pineal gland of the bovine brain as an indole hormone, also called the pineal gland. This hormone is a synchronizer of the endocrine system, and its synthesis and secretion in animals are regulated by the pineal gland's and retina's circadian rhythm sensing external light. Melatonin participates in various physiological activities in the body and is closely related to human growth and development, reproductive function, and brain function. Studies have shown that taking melatonin can produce analgesic, sedative, anti-epileptic, hypnotic, and other effects, and has various physiological processes such as promoting sleep, regulating endocrine, enhancing immunity, anti-oxidation, and scavenging free radicals.


Factory

1. Xi'an Sonwu Biotech Co., Ltd has a factory to manufacture and store the products, so they have adequate stock. Xi'an Sonwu has a well-ordered, tidy, and clean production department. Under the leadership of Xi'an Sonwu, researchers can develop high-quality new products.

2. Xi'an Sonwu has strict production and testing requirements for salespeople. To ensure that each product has data support and after-sales service is provided.

factory


Certificate

certificates-2


Package

packaging-3


Logistics

Logistics3

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics


FAQ

Note that 5-Methoxytryptamine, hallucinogenic in humans, also lowers oxygen tension in mammals' subcutaneous tissue and bone marrow.

There are more and more tryptamine products on the market. If you are interested in 5-methoxytryptamine powder, you can contact Xi'an Sonwu. Click the email to get in touch with the best price and high-quality manufacturer.

Email:sales@sonwu.com

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