Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of lifitegrast powder in China. We warmly welcome yuo to wholesale bulk lifitegrast powder for sale here from our factory. Quality products and reasonable price are available.
What Kind Of Drug Is Lifitegrast
Lifitegrast Powder is a medication primarily used for the dry eye disease, which is also known as dry eye syndrome. It is a small-molecule drug that works as a lymphocyte function-associated antigen-1 (LFA-1) antagonist. By blocking LFA-1, this product inhibits the interaction between T cells and their target cells in the eye's inflammatory process, helping to reduce inflammation and possibly increase tear production. It is typically available as an eye drop solution and can help increase tear production and relieve discomfort. This medication must be used as directed by the prescribing healthcare provider.

As an antagonist of lymphocyte function-associated antigen-1 (LFA-1), lipitegrast is categorized. The LFA-1 protein is present on the surface of T cells and other immune cells. In dry eye, an inflammatory process typically leads to increased levels of immune cells on the ocular surface, causing discomfort and symptoms such as dryness, burning, and itching. By blocking the interaction between LFA-1 and its ligand, intercellular adhesion molecule-1 (ICAM-1), Lifitegrast successfully lowers activation and migration of T cells to the ocular surface. This can reduce inflammation and help improve symptoms and indicators of dry eye.
Certificate Of Analysis
|
Item |
Specification |
Result |
|
Appearance |
White to off-white Powder |
Conforms |
|
Identification |
By HNMR |
Conforms |
|
|
By HPLC |
Conforms |
|
Solubility |
Practically insoluble in water, very soluble in DMF, slightly soluble in ethanol, sparingly soluble in methanol, very slightly soluble in acetonitrile, soluble in 0.1M NaOH water solution, Practically insoluble in 0.1M HCl. |
Conforms |
|
Loss on Drying |
≤0.50% |
0.30% |
|
Residue on ignition |
≤0.10% |
0.08% |
|
Heavy Metal |
≤20ppm |
Conforms |
|
Related Substances |
Maximum single impurity: ≤0.50% |
0.13% |
|
|
Total impurities: ≤1.00% |
0.36% |
|
EE Purity(HPLC) |
≥99.0% |
99.82% |
|
Purity(HPLC) |
≥99.0% |
99.64% |
|
Conclusion |
Conforming to Enterprise Standard |
|
Where To Buy Lifitegrast
Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you want to buy Lifitegrast API.
Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.
|
Form |
Sample Amount |
The Minimum of Quantity |
|
Powder |
5g |
10g |
Customers' Good Comment

What Is Lifitegrast Good For
It is primarily used to treat dry eye disease (also called dry eye syndrome) in adults. Here are the key benefits and uses:
Indications:
1. Dry Eye Disease:
It has been licensed specifically to treat the symptoms of dry eye syndrome, which is characterized by poor quality or insufficient tear production, which may result in eye discomfort and inflammation.

Benefits:
- Reduces Inflammation: It targets the underlying inflammatory process of dry eye, helping to relieve symptoms such as dryness, burning, and discomfort.
- Improves Tear Production: It might encourage more healthy tear production and general ocular surface health by regulating the immunological response.
- Convenient Administration: It comes as a 5% eye drop solution that is usually used twice daily and can be incorporated into patients' daily routine relatively easily.

Lifitegrast is beneficial for patients looking for a treatment that goes beyond traditional lubricating eye drops, providing a targeted approach to managing the underlying inflammation associated with dry eye disease.
Is Lifitegrast A Steroid
No, It is not a steroid. It is a small-molecule drug that acts as a lymphocyte function-associated antigen-1 (LFA-1) antagonist. Lifitegrast is specifically designed to treat dry eye disease by reducing inflammation and modulating the immune response in the eye, rather than the mechanisms that steroids employ.
Key Differences:
- Mechanism of Action:
- This product works by inhibiting the interaction between LFA-1 and its ligands on T cells, thereby reducing ocular inflammation.
- Steroids (corticosteroids) reduce inflammation by broadly suppressing the immune response and inhibiting various inflammatory mediators.
- Uses:
- This product is primarily used for dry eye disease, whereas steroids are used to treat a wide range of inflammatory conditions.
It offers a non-steroidal alternative for managing dry eye disease, making it valuable for patients who may wish to avoid steroids due to potential side effects.
How Long Does It Take For Lifitegrast To Work
It is administered as an eye drop solution, specifically in a concentration of 5%. The standard dosing regimen is twice daily, with one drop in each affected eye. Patients are advised on proper instillation techniques to minimize contamination and maximize effectiveness. It is important to note that the drops should be stored at room temperature and discarded after 12 weeks once opened, as this can help prevent potential eye infections.

Lifitegrast Powder is usded for the dry eye disease. It may take several weeks to see significant improvement in symptoms. While some patients might experience relief within the first two weeks, it is generally recommended to give it around 4 to 12 weeks to assess its full effectiveness. Consistency with the daily application is crucial for achieving the best results. As always, it's important to consult with a healthcare provider for personalized advice and monitoring during treatment.
What's The Side Effects
Like any medication, this product can have side effects. Common side effects include:
- Eye Irritation: A burning or stinging sensation upon instillation.
- Discomfort: General discomfort or a sensation of something in the eye.
- Blurred Vision: Temporary blurriness after applying the drops.
- Taste Disturbance: Some patients report an unusual taste in the mouth.
These side effects are usually mild to moderate and usually lessen with continued use. Serious side effects are rare, but patients should be advised to see a doctor if they experience severe pain, vision changes, or signs of infection.

- Special Considerations
- Pregnancy and Breastfeeding: Pregnancy should only be treated with lipitegrast if the possible advantages outweigh the dangers. As with all medications, the risks and benefits should be discussed with a healthcare provider.
- Age Considerations: It can be used in adults and children over the age of 17. Safety and efficacy in younger children have not been established.
- Drug Interactions: Although there haven't been any noteworthy drug interactions noted for lifitegrast, people should nonetheless let their doctor know about all of the supplements and prescription drugs they're taking.
Comparisons With Other Treatments
Lifitegrast API represents a shift in the management of dry eye disease. It provides a distinct approach compared to traditional treatments for dry eye disease:
1. Artificial Tears: These are the most commonly used products for dry eye. While they provide quick relief by lubricating the eye, they do not address the underlying inflammation associated with DED.
2. Cyclosporine A (Restasis): Another prescription option, cyclosporine A works over a longer time to reduce inflammation and increase tear production. However, this product may be preferred by some patients due to its more rapid onset of action.

3. Corticosteroids: These can effectively reduce inflammation but come with potential side effects, including increased intraocular pressure and risk of cataracts with long-term use.
4.Punctal Plugs: Used to block tear drainage canals, these physical devices help retain tears but do not modify the inflammatory response.
In contrast, it specifically targets the inflammatory pathways associated with dry eye, offering a unique mechanism of action. Other emerging therapies, such as cyclosporine A (Restasis) and autologous serum eye drops, also aim to reduce inflammation but may not be suitable for all patients due to side effects or the need for specialized preparation.
Factory
1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.
2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

Certificate

Package

Logistics Update

In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

Company's Profile
Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry when you want Lifitegrast API.
And if you want to know the Lifitegrast Powder price, please contact XI'an Sonwu.
Email: sales@sonwu.com
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