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Pregabalin Raw Powder

Pregabalin Raw Powder

Appearance: White Powder
Specification: 99%
CAS: 148553-50-8
Molecular Formula: C8H17NO2
Molecular Weight: 159.23
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of pregabalin raw powder in China. We warmly welcome yuo to wholesale bulk pregabalin raw powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Pregabalin Prescribed For

Pregabalin raw powder is a drug commonly used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. At the chemical level, its molecular formula is C8H17NO2, and its chemical name is (2S)-3-(Aminomethyl)-5-methylhexanoic acid. Its structural characteristics make it similar to the neurotransmitter gamma-aminobutyric acid (GABA), but it is not a direct derivative of GABA. Its core structure is a chain of six carbon atoms with an aminomethyl group and a carboxyl group on this chain. This structure gives it the ability to bind to specific receptors in the body. Its pharmacological mechanism mainly involves binding to calcium channels of the α2-δ subunit, which reduces the release of neurotransmitters and thus regulates the excitability of the nervous system. Due to this mechanism of action, pregabalin is able to effectively control epileptic seizures and relieve neuropathic pain. The efficacy of it is closely related to its chemical structure. Its aminomethyl and carboxyl moieties enable it to bind to calcium channel subunits in the brain. This binding reduces the release of neurotransmitters such as glutamate, which is crucial for inhibiting neural excitability. Therefore, it can not only help control epileptic seizures but also relieve pain caused by nerve damage, such as diabetic neuropathy or postherpetic neuralgia. It has a pharmacokinetic profile that includes quick absorption upon oral administration and about 100% bioavailability. It is eliminated unaltered through the urine and does not experience any significant metabolism. It has a half-life of approximately 6 hours, which means that it is relatively short-lived in the body and requires regular dosing to maintain adequate drug concentrations. Its pharmacological studies have also shown that its efficacy in anxiety disorders may be related to its mechanism of affecting the central nervous system.

As one of the most popular products, pregabalin powder has received many good comments and feedback from customs. What attracts customers mostly is the high quality. Except that Xi'an Sonwu has exceedingly competitive prices. If you want to know more about it, just contact Xi'an Sonwu Biotech Co., Ltd.

Chemical-structure-of-pregabalin

 

Certificate Of Analysis

Items

Standards

Results

Appearance

White Powder

Conform

Odor

Characteristic

Conform

Assay

≥99.0%

99.17%

Particle Size

100% pass 80mesh

Conform

Moisture

<5.0%

Conform

Ash Content

<4.0%

Conform

Solvent Residue

Eur.Pharm

Conform

Total Heavy Metals

<10 ppm

Conform

Arsenic

<1.0 ppm

Conform

Lead

<1.0 ppm

Conform

Mercury

<0.5 ppm

Conform

DDT

<0.2ppm

Conform

E. Coli

Negative

Negative

GMO Status

Complies

GMO Free

Irradiation

Complies

Irradiation Free

 

Can You Still Get Pregabalin

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based and quality first is Xi'an Sonwu's principle. Xi'an Sonwu strictly controls product quality, which means selection starts from raw materials. Besides, Xi'an Sonwu handles every detail and reduces costs to the maximum extent so that the customers can get cost-effective products. Based on these, customers have given good feedback on the products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying it.

 

Xi'an Sonwu ultimately ensures the product's quality so the samples can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum Of Quantity

Powder

1kg

500g

 

Customers' Good Comment

Good Comment

 

How Does Pregabalin Work

Pregabalin raw powder is a drug used to treat neuropathic pain, epilepsy, and generalized anxiety disorder. Its mechanism of action is different from other drugs, mainly involving calcium channels in the nervous system, and has significant clinical application value. One primary use of it is to treat neuropathic pain, which is often caused by nerve damage or disease, such as diabetic neuropathy and postherpetic neuralgia. Its mechanism of action is related to its effect on calcium channels in the central nervous system. It reduces the release of neurotransmitters such as glutamate and norepinephrine by binding to the alpha2-delta subunit on neurons. This effect reduces the hyperexcitability of neurons, thereby alleviating the sensation of pain. For many patients, it can significantly reduce pain and improve quality of life. It is also used to control partial seizures, especially when other anti-epileptic drugs are not effective. It reduces the occurrence of epileptic seizures by regulating the release of neurotransmitters. It affects calcium channels in the brain that control neural excitability, thereby stabilizing neural electrical activity and thereby reducing the frequency and severity of seizures. This makes it an essential option in anti-epileptic treatment, especially for patients who do not obtain adequate control from conventional anti-epileptic drugs. Additionally, it is used to treat generalized anxiety disorder. Its mechanism is related to its regulatory effect on the central nervous system. It reduces abnormal excitability of the nervous system by decreasing the release of neurotransmitters, which helps relieve symptoms of anxiety. Although it is not specifically an anti-anxiety medication, its sedative effects can help reduce a patient's anxiety and improve their mood state.

Pregabalin Neuropathic pain

 

Pregabalin's primary mechanism of action is to modulate calcium channel function by binding to α2-δ subunits on neuronal membranes. These α2-δ subunits are an essential part of voltage-dependent calcium channels, especially in the nervous system. Its binding reduces the influx of calcium ions through these channels. The key to this mechanism is that the influx of calcium ions is essential for neuronal excitability and the release of neurotransmitters. Reducing the influx of calcium ions is effective in reducing the overexcitation of neurons, which in turn reduces the release of neurotransmitters such as glutamate and norepinephrine. This action reduces abnormal nerve activity, which helps relieve pain and control epileptic seizures. In the case of neuropathic pain, abnormal signaling in the nervous system leads to persistent pain sensations. It slows the propagation of these abnormal signals through its action on calcium channels. Specifically, it reduces the release of neurotransmitters in the pain transmission pathway, inhibiting the enhancement of pain signals. This mechanism makes it effective in relieving symptoms when treating neuropathic pain, such as diabetic neuropathy and postherpetic neuralgia. For the treatment of epilepsy, its mechanism of action is also related to its regulation of calcium channels. Epileptic seizures are often triggered by abnormal neural electrical activity. It reduces the hyperexcitability of neurons by reducing the influx of calcium ions, which helps stabilize neural electrical activity and reduce the occurrence of epileptic seizures. Specifically, its action reduces the release of neurotransmitters responsible for the propagation of seizures, thereby effectively controlling the frequency and severity of seizures. In the treatment of generalized anxiety disorder, pregabalin reduces patients' anxiety through its sedative effect. It regulates the release of neurotransmitters and reduces the hyperexcitability of the central nervous system.

Pregabalin mechanism of action

 

What are the specific clinical applications of pregabalin? In fact, it was initially approved to treat neuropathic pain, such as diabetic neuropathy and postherpetic neuralgia. Neuropathic pain is caused by abnormal signaling in the nervous system and usually manifests as a persistent burning or tingling sensation. It relieves these symptoms by reducing the influx of calcium ions and inhibiting the enhancement of pain signals. Typically, patients experience substantial improvement in symptoms after using it for a few weeks. It is also used to control epileptic seizures, especially partial epilepsy (i.e., partial seizures). Epileptic seizures are triggered by abnormal neural electrical activity. It stabilizes neural electrical activity by reducing the release of neurotransmitters and reducing the frequency and severity of seizures. As an auxiliary treatment drug, it is often used in combination with other anti-epileptic drugs to improve the therapeutic effect. It can effectively reduce the frequency of attacks and help patients better control their condition. Generalized anxiety disorder is a common psychological disorder characterized by persistent, excessive anxiety and worry. Pregabalin has shown positive results in treating this disease. It helps reduce anxiety symptoms by regulating the excessive excitability of the nervous system. Although it is not a drug specifically developed for anxiety disorders, its regulatory effect on the nervous system can effectively relieve anxiety and improve patients' emotional state and quality of life.

anxiety Pregabalin

 

Factory Environment

Xi'an Sonwu production factory is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers insist on developing new products. The following is the testing environment of the laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for the products and providing the customers with a quality experience.

Factory Environment

 

Certificates

certificates

 

Packaging

packaging

 

Logistics Record

Logistics Record

In addition to guaranteeing product quality, the other most vital thing is clients can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

Why Choose Us

Xi'an Sonwu has been engaged in import-export for over ten years and has rich experience in the import and export industry.

Xi'an Sonwu has ten years of experience in product development, production, and sales.

Xi'an Sonwu has a professional team with a clear division of labor.

Xi'an Sonwu has professional laboratories and equipment to ensure high-quality products.

Products are tested by third parties.

Xi'an Sonwu provides OEM service.

Xi'an Sonwu provides 7*24 customer service.

 

If you want to buy pregabalin raw powder, feel free to contact Xi'an Sonwu.

E-mail: sales@sonwu.com

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