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Tegoprazan Powder

Tegoprazan Powder

Appearance: White Powder
Specification: 99% min
CAS: 942195-55-3
Molecular Formula: C20H19F2N3O3
Molecular Weight: 387.38
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of tegoprazan powder in China. We warmly welcome yuo to wholesale bulk tegoprazan powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Tegoprazan

Tegoprazan powder is also called CJ 12420 powder. This medication, which is often used to lower stomach acid production, is a member of the proton pump inhibitor (PPI) class. It is principally used to treat disorders associated with excess stomach acid, including as peptic ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). It works by inhibiting proton pumps in stomach cells, thereby reducing acid production. This helps relieve symptoms associated with conditions such as heartburn, acid reflux, and ulcers. It is a rapid-acting and long-lasting acid suppressant and is considered the most advanced drug currently available for treating gastroesophageal reflux disease. It can overcome the shortcomings of traditional proton pump inhibitors. The safety and efficacy of CJ 12420 in treating individuals with non-erosive gastric reflux disease (NERD) have been assessed in recent research. The research results show that CJ 12420 has broad market demand and has good prospects in the peptic ulcer drug market. If you need, Xi'an Sonwu can supply Tegoprazan. Xi'an Sonwu is looking forward to hearing from you.

Tegoprazan

 

Certificate Of Analysis

ANALYSIS

SPECIFICATION

RESULT

Appearance

White powder

Complies

Purity (HPLC)

≥99.0%

99.76%

Solubility

Soluble

Complies

Acidity coefficient (pKa)

9.73±0.30

Complies

Loss on drying

0.18%

Complies

Residue on ignition

0.01%

Complies

Water (KF)

0.31%

Complies

Density

1.371±0.06g/cm3

Complies

Boiling point

596.5±50.0°C

Complies

Conclusion

This product conforms to the specifications.

 

Tegoprazan Buy Online

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce costs to the maximum so our customers can get cost-effective products. Based on these, customers have given a lot of good feedback about our products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying Tegoprazan.

Xi'an Sonwu ensures product quality and can provide samples. Here is the quantity.

Tegoprazan Form

Sample Amount

MOQ

Powder

10g

10g

 

Customers' Good Comment

-1001

 

What Is The Use Of Tegoprazan

It is primarily used to treat conditions associated with excess stomach acids, such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is a medication in the proton pump inhibitor (PPI) class.

Here are some common uses for tegolazan:

1. Gastroesophageal Reflux Disease (GERD): Tegoprazan aids in the relief of GERD symptoms, including acid reflux, heartburn, and stomach acid reflux into the esophagus.

Gastroesophageal Reflux Disease GERD

2. Peptic ulcer: Used to treat and prevent peptic ulcers, including gastric ulcers (stomach) and duodenal ulcers (upper small intestine).

3. Helicobacter pylori eradication: Medication combinations that target Helicobacter pylori, the bacteria that can lead to peptic ulcers, may include it.

4. Other Acid-Related Conditions: It may also be used to treat other conditions caused by excessive production of stomach acids, such as Zollinger-Ellison syndrome and gastritis caused by nonsteroidal anti-inflammatory drugs (NSAIDs).

It is an effective gastric acid-regulating drug that can help patients control the symptoms of gastric acid-related diseases and improve their quality of life. However, patients should strictly follow their doctor's recommendations when using it and be aware of possible side effects and contraindications.

 

Tegoprazan Mechanism Of Action

Tegoprazan powder's role is a proton pump inhibitor (PPI). Here's how it works:

1. Inhibition of Proton Pump: It inhibits the proton pump, sometimes referred to as the H+/K+ ATPase enzyme system, which is located in the parietal cells of the stomach lining. The last stage in the synthesis of gastric acid is carried out by this pump, which exchanges potassium ions for hydrogen ions (protons) in the stomach lumen.

Inhibition of Proton Pump

2. Reduction of Gastric Acid Production: By stopping the proton pump's action, it reduces the secretion of gastric acid into the stomach lumen. The acidity of the stomach's contents decreases as a result of this decrease in gastric acid production.

3. Decreased Acid-Related Symptoms: Reducing the acidity of the stomach aids in the relief of symptoms related to acid-related illnesses, peptic ulcers, and gastroesophageal reflux disease (GERD).

4. Promotion of Healing: CJ 12420's ability to reduce gastric acid production can also aid in the healing of erosive esophagitis and gastric or duodenal ulcers by providing a less acidic environment conducive to tissue repair.

CJ 12420's mechanism of action as a proton pump inhibitor helps to regulate stomach acid secretion, making it effective in managing acid-related gastrointestinal conditions. However, it's crucial for patients to use it under medical supervision and to be aware of potential side effects and contraindications.

 

Tegoprazan VS Esomeprazole

Medication associated to overproduction of stomach acid is treated with ①tegoprazan and ②esomeprazole. Still, they belong to different classes of drugs and have some differences in their characteristics. Here's a comparison:

1. Class of Drug:

①: It is a potassium-competitive acid blocker (P-CAB), a relatively newer class of drugs that inhibits the proton pump in the stomach.

②: Proton pump inhibitors (PPIs), like esomeprazole, function by preventing the stomach's proton pump from functioning.

2. Mechanism of Action:

①: It inhibits the H+/K+ ATPase enzyme system, commonly known as the proton pump, in the parietal cells of the stomach lining.

②: Esomeprazole also works by inhibiting the proton pump in the stomach, thereby reducing gastric acid secretion.

Tegoprazan VS Esomeprazole

3. Duration of Action:

①: It has a relatively long duration of action, providing sustained acid suppression over time.

②: Esomeprazole also has a long duration of action but may require daily dosing for optimal effect.

4. Onset of Action:

①: It typically has a rapid onset of action, with effects seen within hours of administration.

②: Esomeprazole may take longer to reach its full therapeutic effect than CJ 12420.

5. Pharmacokinetics:

①: It is metabolized in the liver and eliminated primarily through the feces.

②: Esomeprazole is also metabolized in the liver and eliminated primarily through the urine and feces.

6. Clinical Uses:

Peptic ulcers, acid-related illnesses, and gastroesophageal reflux disease (GERD) are among the conditions that are treated with both esomeprazole and CJ 12420.

 

Tegoprazan Side Effects

As with any medication, Tegoprazan may cause side effects, although not everyone experiences them. Common side effects associated with CJ 12420 use may include:

1. Headache: Some individuals may experience headaches as a side effect of it.

2. Nausea and Vomiting: It can occasionally cause nausea and vomiting in some patients.

3. Abdominal Discomfort: This may include stomach pain, bloating, or discomfort in the abdomen.

4. Diarrhea or Constipation: Some persons may experience constipation or diarrhea as a result of changes in their digestive habits.

5. Flatulence (Gas): Increased gas production or flatulence may occur as a side effect.

Flatulence Gas

6. Dizziness: Some people may feel dizzy or lightheaded while taking it.

7. Fatigue: It can sometimes cause fatigue or feelings of tiredness.

8. Increased Risk of Bone Fractures: Proton pump inhibitors (PPIs) like CJ 12420 have been linked to a modest increase in the incidence of bone fractures over the long term, especially in older persons or those who use high doses for prolonged periods of time.

9. Vitamin and Mineral Deficiencies: Extended usage of it may result in reduced absorption of some vitamins and minerals, including magnesium, calcium, and vitamin B12. This could lead to deficiencies.

10. Increased Risk of Infections: Long-term PPIs like CJ 12420 may slightly increase the risk of certain infections, such as pneumonia and gastrointestinal diseases.

 

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

factory a

factory b

 

Certificate

certificates

 

Packing

packaging

 

Logistics Update

-1002

In addition to guaranteeing product quality, the other most vital thing is that clients receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

FAQ

1. How to inquire?

We can be reached by phone, email, or social media.

2. How do you guarantee the quality of products?

Each batch must be tested, and COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We cooperate with third parties as well, like SGS.

3. How do you pack and store?

Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.

Storage: You can keep it in a dry and cool place and make it avoid sunlight.

If you want to know about the Tegoprazan powder, you can contact Xi'an Sonwu. Click the email, and then you get high-quality CJ 12420 powder.

Email: sales@sonwu.com

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