Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of tapinarof powder in China. We warmly welcome yuo to wholesale bulk tapinarof powder for sale here from our factory. Quality products and reasonable price are available.
Benvitimod Tapinarof
Tapinarof powder, also called Benvitimod powder and WBI 1001 powder. This novel medication is mainly used to treat inflammatory skin conditions including psoriasis and eczema. It is a non-steroidal anti-inflammatory drug that regulates the skin's inflammatory and immune responses. The mechanism of action includes reducing skin inflammation, inhibiting abnormal keratinization, and regulating immune cell activity. Clinical trials have shown that it significantly reduces skin inflammation symptoms such as psoriasis and eczema and is relatively safe. It has attracted attention because of its ability to reduce side effects compared with traditional corticosteroids. Although It shows promise in treating skin conditions, further clinical studies are needed to confirm its long-term efficacy and safety. If you need, Xi'an Sonwu can supply tapinarof. Xi'an Sonwu is looking forward to hearing from you.

Certificate Of Analysis
|
ITEMS |
SPECIFICATIONS |
RESULTS |
|
Appearance |
Light brown powder |
Conforms |
|
Identification |
Conform to the standard |
Conforms |
|
Purity |
≥99% |
99.90% |
|
1 H NMR Spectrum |
Consistent with structure |
Conforms |
|
LCMS |
Consistent with structure |
Conforms |
|
Conclusion |
This product conforms to the specifications. |
|
Tapinarof Price
Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce costs to the maximum so our customers can get cost-effective products. Based on these, customers have given a lot of good feedback about our products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying tapinarof.
Xi'an Sonwu ensures product quality and can provide samples. Here is the quantity.
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Tapinarof Form |
Sample Amount |
MOQ |
|
Powder |
1kg |
1kg |
Customers' Good Comment

What Is Tapinarof Used For
It is mainly used in the following areas:
1. Psoriasis: It is a topical drug commonly used to treat psoriasis. A persistent inflammatory illness called psoriasis is typified by thick, red skin patches that occasionally have silvery-white scales on surface.

2. Eczema: Some studies have shown that it may also have a specific therapeutic effect on eczema (incredibly non-specific eczema). Eczema is a skin ailment that causes inflammation and is typified by dry, itchy, red, and irritated skin.
3. Other inflammatory skin diseases: It may also have therapeutic potential in other inflammatory skin diseases, but its main application is treating psoriasis.
Its main functions in treatment include:
1. Anti-inflammatory effect: It helps relieve pain, redness, swelling, and other inflammation-related symptoms by reducing the inflammatory response of the skin.
2. Regulate the immune system: It might lessen the development of psoriasis plaques by modulating immune system function, which in turn controls the growth and differentiation of skin cells.
3. Slow down the proliferation of skin cells: It can slow down the excessive proliferation of skin cells and reduce the thickness and number of psoriasis plaques.

4. Local treatment: It is a local treatment that can be applied locally to the afflicted location to lessen the potential for systemic medication adverse effects.
5. Well tolerated: It is well tolerated by most patients, and common adverse reactions are mild, usually local skin irritation or burning sensation.
6. Long-term efficacy: Some studies suggest that long-term use of it may help maintain stable disease control and reduce the risk of relapse.
It is a drug with multiple effects, such as anti-inflammatory, regulating immune function, and slowing down skin cell proliferation. It is suitable for topical treatment of psoriasis and is well tolerated.
Tapinarof Mechanism Of Action
Tapinarof powder' s mechanism of action involves its ability to modulate the activity of specific nuclear receptors, particularly the aryl hydrocarbon receptor (AhR) and the retinoic acid-related orphan receptor alpha (RORα).
1. Aryl hydrocarbon receptor (AhR): It activates AhR, which regulates the immune response and inflammation. When AhR is activated by it, pro-inflammatory cytokines are suppressed and anti-inflammatory cytokines are produced, which ultimately results in a reduction of skin inflammation.

2. Retinoic acid-related orphan receptor alpha (RORα): It also acts as a partial agonist of RORα. RORα regulates the differentiation and function of various immune cells, including T and dendritic cells. It serves to balance the immunological response in the skin and lessen the aberrant proliferation of keratinocytes, which is typical of disorders like psoriasis, by modifying RORα activity.
Benvitimod's dual mechanism of action through AhR activation and RORα modulation results in anti-inflammatory effects and normalization of keratinocyte proliferation, making it effective in treating inflammatory skin conditions such as psoriasis.
What Are The Contraindications For Tapinarof
Contraindications for it include:
1. Hypersensitivity: Individuals with hypersensitivity or allergic reactions to WBI 1001 or its components should not use the medication.
2. Open Wounds or Broken Skin: Applying it to open wounds, cuts, or regions of damaged skin is not advised because it may irritate or create discomfort.
3. Infection: It should not be used in areas of the skin affected by bacterial, fungal, or viral infections unless directed by a healthcare professional. Using it on infected skin can exacerbate the infection or interfere with its treatment.
4. Pregnancy and Breastfeeding: The safety of it during pregnancy and breastfeeding has not been established. Therefore, it should be used cautiously during these periods and only if the potential benefits outweigh the possible risks.

5. Pediatric Use: The effectiveness and safety of it in pediatric patients have not been established. Therefore, it is not recommended for use in children under 18 unless specifically prescribed by a healthcare professional.
Always consult a healthcare provider or dermatologist before using it to ensure it is safe and appropriate for your medical condition and circumstances.
Tapinarof Side Effects
Common side effects of Tapinarof may include:
1. Skin Irritation: At the application site, this could appear as redness, itching, burning, or stinging.
2. Dry Skin: Some individuals may experience dryness or flakiness of the skin where it is applied.

3. Erythema (Skin Redness): Mild to moderate skin redness may occur, especially during the initial stages of treatment.
4. Peeling or Scaling: Some users may notice peeling or scaling of the skin, particularly in areas affected by psoriasis or eczema.
5. Contact Dermatitis: In rare cases, individuals may develop allergic contact dermatitis, characterized by an itchy or blistering rash at the application site.
6. Hypersensitivity Reactions: Severe allergic reactions to it are rare but can happen. These responses might cause symptoms like breathing difficulties, edema, or extreme skin irritation.
7. Worsening of Psoriasis: In some cases, psoriasis symptoms may temporarily worsen before improving with it treatment.
Factory
1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.
2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

Certificate

Packing

Logistics Update

In addition to guaranteeing product quality, the other most vital thing is that clients receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ
1. How to inquire?
We can be reached by phone, email, or social media.
2. How do you guarantee the quality of products?
Each batch must be tested, and COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We cooperate with third parties as well, like SGS.
3. How do you pack and store?
Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.
Storage: You can keep it in a dry and cool place and make it avoid sunlight.
If you want to know about the tapinarof powder, you can contact Xi'an Sonwu. Click the email, and then you get high-quality Benvitimod powder.
Email: sales@sonwu.com
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