Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of urolithin powder in China. We warmly welcome yuo to wholesale bulk urolithin powder for sale here from our factory. Quality products and reasonable price are available.
What Is Urolithin?
Urolithin powder has two types urolithin A(UA) and urolithin B(UB). The gut microbiota produces urolithin, naturally metabolizing ellagitannins in fruits and nuts. In the body, ellagitannins are converted to ellagic acid by intestinal flora, and ellagic acid is converted to UA and UB. However, the bioavailability of ellagitannins and ellagic acid is very low. Some of the unabsorbed ellagic acids are metabolized into urolithins under the action of the gastrointestinal flora. Therefore, urolithins may be the material basis for biological activities. Related studies on urolithin activity, metabolic processes, and tissue distribution have attracted extensive attention in recent years. Scientists have paid attention to its benefits of it. As a professional urolithin manufacturer, Xi'an Sonwu can provide high-quality products at competitive prices. If you want to purchase, please feel free to contact Xi'an Sonwu.
COA of Analysis
What Is Urolithin A?
Urolithin A is a metabolite formed by the conversion of ellagic acid by intestinal bacteria. It belongs to a class of organic compounds, which is also known as benzocoumarins or dibenzo-alpha-pyrones. Its precursors ellagic acid and ellagicin are ubiquitous and are found in plants, such as pomegranates, strawberries and walnuts.
It can improve mitochondrial function and increases strength and endurance in aging muscles. It is the only natural product shown to restart mitophagy and reverse muscle aging. UA has been the subject of preliminary research on biological effects since 2000.
What Is Urolithin B?
Urolithin B is a phenolic compound produced after the human gut absorbs foods containing ellagitannins (such as pomegranates, strawberries, red raspberries, walnuts or oak-aged red wine) as Urophospholipid B as Urophospholipid B glucuronide form present in urine. It is a natural product with anti-inflammatory and neuroprotective effects. According to research, UB can cross the brain barrier and may be neuroprotective against Alzheimer's disease.
Mechanism of action of Urolithin
1. Induction of mitophagy
With some age-related diseases, mitophagy declines or stalls, and slowly organ function declines with it. Mitophagy is a form of phagocytosis that helps eliminate damaged mitochondria so they can function optimally. Autophagy refers to the process by which cytoplasmic contents are degraded and recycled, while mitophagy is the degradation and recycling of mitochondria. UA can activate mitophagy through various pathways, such as activating enzymes that promote mitophagy, or regulating the mitophagy pathway, and promoting autophagosome formation.
2. Antioxidant properties
Oxidative stress will occur if there is an unbalance of antioxidants and free radicals in the body. These excess free radicals are associated with many chronic diseases, such as diabetes and heart disease . Urolithins exhibit antioxidant effects through reducing intracellular reactive oxygen species (ROS) levels and inhibiting lipid peroxidation in certain cell types.
3. Anti-inflammatory properties
Inflammation is a natural process. During this process, our body fights against anything like microbes. However, chronic inflammation can be detrimental to the body, as it has been linked to various conditions, such as asthma and heart disease. Urolithins may exhibit anti-inflammatory properties by inhibiting the production of nitric oxide.
4. Antibacterial effect
Microorganisms, including bacteria, fungi and viruses, exists naturally in the environment and even in the human body. However, a small number of microorganisms called pathogens can cause infectious diseases, such as influenza, measles and malaria. Urolithin can exhibit antibacterial activity by inhibiting quorum sensing. Quorum sensing is a form of bacterial communication that enables bacteria to detect and control infection-related processes.
Benefits of Urolithin
Urolithin powder can be divided into urolithin A powders and urolithin B powders. UA and UB are closely related, and both are used in supplements but have different functional benefits. They work with varying mechanisms of action.
Benefits of UA
(1). It can prolong the lifespan of mitochondria.
Mitochondria are often damaged by age and stress. UA induces mitochondrial phagocytosis by selectively removing damaged mitochondria, and this also ensures the circulation of mitochondria for optimal function. Getting rid of damaged mitochondria plays an essential role in extending lifespan.
(2). It can be cognitively enhanced.
UA protects neurons from dying and can also trigger neurogenesis through anti-inflammatory signaling. In a study with memory impairment, it was found to improve cognitive impairment and protect neurons from apoptosis. It means that UA can be used to treat Alzheimer's disease.
Benefits of UB
(1). It prevents muscle loss.
There are variety of reasons for muscle loss, such as disease, aging, and protein deficiencies in the diet. You can take many steps to stop or limit muscle loss, such as exercise, medications, amino acids, and polyphenols. In a study, taking UB supplements over a period was found to enhance muscle development in mice. UB can be classified as a polyphenol and plays a role in preventing muscle loss by activating muscle protein synthesis and slowing down degradation.
(2). It can enhance memory.
UB has been reported to improve the permeability of the blood barrier to enhance cognitive function. According to the research, it is shown that the powder can be a potential memory enhancer by improving general cognitive function.
Application of Urolithin
Urolithin is a natural product with antiproliferative and antioxidant activity, formed from the metabolism of polyphenols in some nuts and fruits. It has many health benefits for our body, like extending lifespan, improving memory, preventing muscle loss, etc. Due to its advantages, the powder has been widely used in various fields, among which the three most typical areas are:
❶ Dietary Supplements
❷ Cosmetics
❸ Sports Nutrition
Side Effects of Urolithin
UA and UB are generally considered safe by the FDA without any side effects. However, if you want to add it to your daily diet, please consult your doctor in advance.
Customer Review
Logistics
Factory
1.Xi'an Sonwu Biotech Co.,Ltd has its own factory,so it has adequate stock. Also,Xi'an Sonwu has clean and tidy producing department with advanced equipment. With the lead of Xi'an Sonwu, researchers are constantly developing new products to meet customer's need. |  |
| 2.Xi'an Sonwu Biotech Co.,Ltd has advanced test equipment and professional testers, which all show that Xi'an Sonwu aims to supply accurate and effective data and good service. |
Certificates
Packaging
Service
Pre-Sales service：
1. OEM service;
2. Supporting sample testing;
3. Each batch of products is tested to ensure quality;
4. Product packaging can be customized according to customer requirements;
5. Inquiry will be replied within 24 hours to provide customers with customized products and services;
6. Providing commercial invoice, packing list, bill of lading, COA and other supporting documents. If the market has special requirements, please let us know in time.
After-Sales service:
1. Real-time update of logistics information;
2. Any products with quality problem can be returned;
3. Any questions about products can be consulted at any time.
If you need to buy urolithin powder, you can contact Xi'an Sonwu directly.
E-mail: sales@sonwu.com
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