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Crisaborole Powder

Crisaborole Powder

Appearance: White or off-white powder
Specification: 98% min
CAS: 906673-24-3
Molecular Formula: C14H10BNO3
Molecular Weight: 251.05
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of crisaborole powder in China. We warmly welcome yuo to wholesale bulk crisaborole powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Crisaborole

 

Crisaborole Powder is an anti-inflammatory medication used topically to treat mild to moderate eczema, specifically atopic dermatitis. It is a phosphodiesterase 4 (PDE-4) inhibitor. It works by reducing inflammation and controlling side effects like redness, tingling, and expanding associated with eczema. It assists with further developing the skin hindrance capability and reduce the inflammatory response in the skin. Crisaborole is applied as a thin layer to the affected skin twice daily and has been shown to be effective in relieving eczema symptoms. It is important to be aware of potential risks and benefits of this product, and consulting a healthcare professional for personalized guidance is recommended.

crisaborole Powder Structure

 

Certificate Of Analysis

 

Characteristic/method

Specification

Result

Aρpearance

White or off-white powder

Conforms

Identification

By IR

Conforms

 

By HPLC

Conforms

Assay

≥98%

99.85%

Solubility

Soluble

Conforms

Loss on Drying

≤1.0%

0.55%

Residual Solvents

Methanol:≤3000ppm

ND

 

Ethanol:≤5000ppm

4000ppm

Related Substances

Any single impurity:≤0.3%

0.1%

 

Total impurities:≤1.0%

0.28%

Pseudomonas aeruginosa

Negative

Negative

Staphylococcus aureus

Negative

Negative

Conclusion

Conforming to Enterprise Standard

 

Where To Buy Crisaborole

 

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you need Crisaborole Supplement.

 

Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum of Quantity

Powder

5g

10g

 

Customers' Good Comment

 

Good Comment

 

What Is The Mechanism Of Crisaborole

 

The mechanism of action of it involves its function as a phosphodiesterase 4 (PDE-4) inhibitor. Here is an overview of how it works:

1. Phosphodiesterase 4 (PDE-4) Inhibition: It inhibits the enzyme phosphodiesterase 4 (PDE-4), which plays a role in the breakdown of cAMP within cells.

2. Increase in cAMP Levels: By inhibiting PDE-4, crisaborole helps to increase the levels of cAMP in cells. cAMP is a signaling molecule that assumes a critical part in controlling different cell processes, including inflammation.

 

Phosphodiesterase-4-PDE4-inhibitors-have-the-potential-to-suppress-inflammatory-cells

 

3. Anti-Inflammatory Effects: Higher levels of cAMP lead to the inhibition of pro-inflammatory cytokines and mediators, thereby reducing the inflammatory response in the affected tissues.

4. Reduction in Inflammation: By decreasing the production of inflammatory cytokines and promoting anti-inflammatory pathways, crisaborole helps to alleviate inflammation and related symptoms, such as redness, swelling, and itching.

In summary, this product exerts its anti-inflammatory effects by inhibiting PDE-4, increasing cAMP levels, and reducing the production of pro-inflammatory mediators, ultimately leading to a decrease in inflammation in conditions like eczema.

 

What Are The Benefits Of Crisaborole

 

Crisaborole offers several benefits in the treatment of mild to moderate eczema (atopic dermatitis). Here are the key benefits:

1. Anti-Inflammatory Action: it functions as a phosphodiesterase 4 (PDE-4) inhibitor, reducing inflammation and relieving side effects related with dermatitis, like redness, tingling, and expanding.

2. Topical Application: As a topical medication, it is applied directly to the affected skin, allowing for localized treatment to the areas requiring attention.

3. Effective Symptom Relief: Clinical studies have demonstrated the effectiveness of crisaborole in alleviating the signs and symptoms of eczema, including itchiness and the extent of the affected skin.

 

Crisaborole Topical Application

 

4. Potential for Prevention of Flare-ups: By addressing inflammation and related symptoms, crisaborole may contribute to the prevention or reduction of eczema flare-ups, thereby promoting improved skin condition and overall comfort.

5. Convenient Dosage Regimen: It is typically applied twice daily, offering a relatively straightforward and manageable treatment plan for individuals with eczema.

It's important to consult with a healthcare professional to understand the specific benefits that crisaborole can offer in an individual's unique circumstances, as well as to address any questions or concerns related to its use.

 

How Effective Is Crisaborole

 

Crisaborole powder is a phosphodiesterase 4 (PDE-4) inhibitor that works by reducing inflammation in the body. It has demonstrated effectiveness in the treatment of mild to moderate eczema (atopic dermatitis) in clinical studies. Research has shown that crisaborole can significantly reduce the eczema's signs and symptoms, such as itching, redness, and the extent of the affected skin.

 

​ Crisaborole indications

 

In clinical trials, patients treated with crisaborole exhibited improvement in the symptoms of their eczema as compared to those who received a placebo. Notably, crisaborole has been found to provide relief from itching and inflammation, leading to an improvement in the overall condition of the skin affected by eczema. It's important to note that individual responses to medication can vary, so it's recommended to consult a healthcare professional for personalized guidance and to examine the expected advantages and contemplations of using crisaborole supplement for eczema treatment. 

 

What Are The Risks Of Crisaborole

 

When using crisaborole, there are potential risks and side effects to be aware of. It's essential to discuss these with a healthcare professional before initiating treatment. Here are some of the possible risks associated with crisaborole:

 

1. Skin Irritation: A few people might encounter gentle skin bothering, such as itching or burning, at the application site.

2. Hypersensitivity Reactions: In rare cases, individuals may develop an allergic reaction to crisaborole, leading to symptoms such as rash, swelling, or difficulty breathing. Immediate medical attention is necessary if signs of a severe allergic reaction occur.

3. Application Site Reactions: Application site pain or exfoliation may occur in some individuals.

4. Ocular Irritation: Avoid contact with the eyes when applying crisaborole, as it may cause eye irritation.

 

Crisaborole Powder Ocular Irritation

 

5. Potential Systemic Effects: Although crisaborole is used topically, it is important to discuss with a healthcare professional regarding any potential systemic effects, especially with prolonged use or in individuals with significant skin barrier impairment.

It's significant to speedily talk with a healthcare provider if any adverse effects or concerns arise during the use of crisaborole. This is not an exhaustive list of potential risks, and individual experiences may vary. Always adhere to the guidance of a healthcare professional for personalized advice and care.

 

How Many Times A Day Should Crisaborole Be Applied

 

When using crisaborole for the treatment of eczema (atopic dermatitis), it is typically applied as a thin layer applied twice daily to the affected skin. The medication should be gently and thoroughly rubbed into the skin until it is fully absorbed. It's essential to adhere to the particular directions gave by a healthcare professional or as indicated on the medication label for the most effective and safe use of crisaborole.

 

Factory

 

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

 

factory a

factory b

 

Certificate

 

certificates

 

Package

 

packaging

 

Logistics Update

 

Logistics Update

 

In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

 

courier

 

Company's Profile

 

Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry.

 

And if you want to know the Crisaborole Powder price or you need Crisaborole Supplement, please contact XI'an Sonwu.

Email: sales@sonwu.com

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