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Urolithin A 8 Methyl Ether Powder

Urolithin A 8 Methyl Ether Powder

Appearance: Light yellow powder
Specification: Min 98%
CAS: 35233-17-1
Molecular Formula: C14H10O4
Molecular Weight: 242.23
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

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Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of urolithin a 8 methyl ether powder in China. We warmly welcome yuo to wholesale bulk urolithin a 8 methyl ether powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Methyl Urolithin A

Urolithin a 8 methyl ether powder (UAMME), or Urolithin C, is a metabolite of ellagitannins - natural compounds found in fruits like strawberries, pomegranates, and raspberries. Gut bacteria convert ellagitannins into urolithins in the human body. UAMME is a promising alternative to Urolithin A due to its higher bioavailability, making it an attractive compound for therapeutic applications.

UAMME is produced by methylation of Urolithin A using the natural enzyme catechol-O-methyltransferase or synthetic procedures. It has a higher lipophilicity than Urolithin A, enhancing its absorption and bioavailability in the human body. The methylation of Urolithin A increases its stability in the human body, improving its half-life. 8-O-Methylurolithin A has several health benefits, including antiinflammatory, antioxidant, and anti-aging properties. One study found that it reduces inflammation by inhibiting the production of inflammatory cytokines. The study also discovered that it reduces oxidative stress by increasing antioxidant enzymes like catalase and superoxide dismutase. UAMME's antiinflammatory and antioxidant properties make it a promising compound for treating and preventing several inflammatory diseases, including arthritis and cardiovascular disease. If you have any questions about 8-O-Methylurolithin A, you can consult Xi'an Sonwu. You will have a professional understanding of this product.

Urolithin A 8 Methyl Ether structure


Certificate Of Analysis

ANALYSIS

SPECIFICATION

RESULT

Physical and chemical anylysis

Appearance

Light yellow powder

Qualified

Assay    (HPLC)

98.0%

98.37%

Melting Point

242 °C(lit.)

Qualified

Density

1.375

Qualified

Moisture Content

≤ 0. 03%

0.01%

Ash content

≤0. 10%

0. 01%

Solubility

Soluble in N,N- dimethyl formamide, dimethyl sulfoxide, slightly soluble in

methanol, ethanol, ethyl acetate

Qualified

Total Impurities

≤0. 10%

0. 16%

Ash content

≤0. 10%

0. 01%

Microbiological Tests

Total Plate Count

≤10000cfu/g

Qualified

Total Yeast & Mold

≤1000cfu/g

Qualified

E.Coil

Negative

Negative

Salmonella

Negative

Negative

Gereral status

GMO free

Complies

Complies

Non-Irradiation

Complies

Complies


Where To Buy 8-O-Methylurolithin A

Xi'an Sonwu Biotech Co. ltd. operates as a manufacturer and distributor and has stable partnerships with numerous countries spanning the Americas, Asia, Europe, and Oceania. Xi'an Sonwu prioritizes product quality and strives to satisfy every customer. Every process step is strictly controlled, from selecting premium raw materials to achieving high-quality products through material selection, manufacturing, sample testing, and personnel expertise. Additionally, every detail is handled meticulously to minimize costs and provide customers with high-value products. Customers have given positive feedback on the product as a result. So if you need antiinflammatory effects, please get in touch with Xi'an Sonwu.

Xi'an Sonwu ultimately makes certain product quality and supplies the samples. Here is the quantity.

8-O-Methylurolithin A Form

Sample Amount

MOQ

Powder

10g

100g

Bulk Capsules

200 capsules

200 capsules

Bottle Capsules

5 bottles

5 bottles


Customers' Good Comment

Xi'an Sonwu1


8-O-Methylurolithin A Function

1. Anti-Malignant Sarcoma Properties

Urolithin C has been found to have potent anti-malignant sarcoma properties, which are attributed to its ability to inhibit the activity of several cell lines. One study found that UAMME reduces the viability of bad breast cells by inducing apoptosis through the fragmentation of DNA. Another study found that UAMME inhibits the growth of colon lesions cells by inducing apoptosis through the activation of caspase-3, a key enzyme involved in the process of apoptosis.

Furthermore, UAM is effective in suppressing the growth of prostate lesions cells specifically. The compound targets the androgen receptor, a protein that plays a crucial role in the development and survival of prostate lesions cells. By inhibiting the activity of this receptor, UAM can prevent the growth and progression of the prostate.


2. Promotes Muscle Health

Urolithin a 8 methyl ether powder has been found to promote muscle health and prevent muscle wasting. As we age, our muscle mass declines, leading to sarcopenia, which affects our ability to perform daily activities. 

UAMME promotes muscle function and prevents muscle wasting. Several studies have shown that it improves muscle function and endurance by enhancing mitochondrial biogenesis - creating new mitochondria in the body. One study found that Urolithin C improves muscle function and endurance in mice by enhancing mitochondrial biogenesis. Another study found that it improves the running performance of rats by increasing the number of mitochondria in their skeletal muscles. UAMME's ability to enhance mitochondrial biogenesis is a promising compound for treating and preventing muscle wasting and age-related muscle decline.

Urolithin A 8 Methyl Ether Promotes Muscle Health


3. Anti-Aging Properties

Research has also suggested that 8-O-Methylurolithin A may have anti-aging properties due to its ability to enhance mitochondrial function and inhibit inflammation. By reducing the damage caused by oxidative stress and inflammation, UAM can help prevent age-related diseases and promote healthy aging.

Studies have shown that it extends the lifespan in several animal models, including mice, C Elegans, and fruit flies. One study found that it extends the lifespan of mice by 45% by reducing age-related inflammation and oxidative stress. Another study found that UAMME extends the lifespan of C Elegans by 10% by activating metabolism and energy homeostasis regulators. UAMME's ability to promote longevity and improve health span makes it a promising compound for treating and preventing age-related diseases.


4. Antiinflammatory Properties

Research has also shown that 8-O-Methylurolithin A has potent antiinflammatory properties, which can be beneficial in treating conditions such as arthritis, asthma, and other inflammatory disorders.

Inflammation is a natural response to disease, infection, or injury. However, it can lead to tissue damage and several conditions when it becomes chronic. UAM can inhibit the activity of inflammatory enzymes, such as COX-2, and cytokines, such as TNF-alpha, contribute to inflammation. 

Urolithin A 8 Methyl Ether Antiinflammatory Properties


5. Enhances Mitochondrial Function

UAM has also been found to enhance mitochondrial function, the energy-producing centers of our cells. Mitochondrial dysfunction has been linked to several diseases, including Parkinson's and Alzheimer's disease. However, UAM can help improve mitochondrial function by stimulating mitophagy, the process of removing and recycling damaged mitochondria.

Furthermore, UAM can improve energy metabolism and help prevent oxidative stress, damaging our cells and leading to several diseases.


8-O-Methylurolithin A  Mechanism

UAME is a metabolite produced by the gut microbiota from ellagitannins found in certain fruits such as pomegranates, walnuts, and strawberries. It works by activating the biological pathway known as mitophagy, which is responsible for removing damaged mitochondria in cells. There to increased cellular energy and improved cell function.

One proposed mechanism of action for UAMME involves its ability to activate the PPAR-gamma, peroxisome proliferator-activated receptor-gamma pathway, which is involved in regulating glucose and lipid metabolism. This activation leads to increased insulin sensitivity in muscle and fat cells, which can improve glucose uptake and utilization and reduce inflammation.

Urolithin A 8 Methyl Ether Mechanism


Factory 

1. Xi'an Sonwu Biotech Co., Ltd has a factory for producing, manufacturing, and storing its products, ensuring sufficient stock levels. The production department at Xi'an Sonwu is well-organized, clean, and orderly, allowing researchers to develop top-quality new products continually.

2. At Xi'an Sonwu, stringent personnel allocation requirements are in place for production, testing, and sales teams, ensuring each product receives the necessary support. Comprehensive data backing and exceptional after-sales services are also provided to guarantee product excellence.

factory 1

factory 2


Certificate

Xi'an Sonwu4


Package

Xi'an Sonwu5


Logistics

Xi'an Sonwu2

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs. 

logistics


FAQ

The potential side effects of Urolithin C need to be better understood. However, some studies have suggested that UAM may cause minor side effects such as digestive discomfort, including diarrhea, bloating, and abdominal cramps. These gastrointestinal side effects may be mild and subside independently after a few days of usage. It may interact with other supplements, and it is not recommended to exceed the recommended dosage. Pregnant women and people with chronic illnesses should also avoid using UAM due to a lack of research on its safety.

If you experience severe symptoms, such as an allergic reaction, chest tightness, or breathing difficulties, seek medical attention immediately. Always consult a healthcare professional if you need to take 8-O-Methylurolithin A, especially if you have a pre-existing medical condition or are taking other medications.

If you want to know a 8-O-Methylurolithin A  manufacturer, you can contact Xi'an Sonwu. Click the email then you get high-quality urolithin a 8 methyl ether powder.

Email: sales@sonwu.com

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