JBSNF-000088

What Is JBSNF 000088

JBSNF-000088, commonly known as 6-methoxy-nicotinamide or 6-MNA, is a member of the nicotinamide family. It is a niacin (vitamin B3) derivative that has a methoxy group (-OCH3) linked to the nicotinamide ring in the sixth position.

The primary uses of 6-methylnicotinamide are as potential treatments for sleep disorders. It works as an agonist (activating substance) for melatonin MT2 receptors, which are specific brain receptors. By interacting with these receptors, 6-MNA can influence how the circadian rhythms and regulation of the sleep-wake cycle are regulated, thereby enhancing the quantity and quality of sleep.

According to research, it probably has sleep-inducing qualities and can be used to treat a variety of sleep disorders, including jet lag and insomnia. besides, it has been investigated for its potential to enhance sleep onset, lengthen overall sleep, and lessen daytime drowsiness.

Xi’an Sonwu guarantees to supply top quality products. If you are interested in this product, feel free to contact Xi’an Sonwu.

Where To Buy 6-Methoxynicotinamide

Xi'an Sonwu Biotech Co. ltd. has rich experience in global trade and health industry. Insist on faith-based and quality first is our company’s principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce cost to the maximum extent, then our customers can get cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. ltd. when you need this product.

Xi'an Sonwu completely makes sure product’s quality, so sample can be supplied. Here is the quantity.

Customers’ Good Comment

OEM Service

Xi'an Sonwu not only can supply high quality JBSNF-000088 powder, but also supply JBSNF 000088 capsules.

So any customers could customize capsules they want. And items below can be supplied.

1. Customized capsules shells (size, color, material)

2. Customized bottles(size, color, material, style)

3. Customized packaging(vacuum foil packaging, box, drum)

4. Customized label(paint film, matte film, optical mask)

What Is NNMT Inhibitor

A substance known as a NNMT (nicotinamide N-methyltransferase) inhibitor is made to stop or reduce the activity of the NNMT enzyme. An enzyme called NNMT is present in cells and is involved in the metabolism of the vitamin B3 form nicotinamide. The function of NNMT can affect a number of physiological functions and illnesses.

Metabolic problems like obesity and insulin resistance are one area of focus for NNMT inhibition. Increased NNMT expression has been linked to metabolic dysfunction and obesity, according to research. NNMT inhibitors have shown promise in improving metabolic markers such as body weight, glucose homeostasis, and lipid metabolism in preclinical investigations. These substances may aid in regulating energy balance and reducing metabolic irregularities by blocking NNMT.

What Is The Effect Of 6-Methoxynicotinamide

Studies have been done on 6-Methoxynicotinamide (6-MNA) to see if it has any potential effects on controlling sleep and other physiological functions. The following are a few effects linked to 6-MNA:

1. Sleep Regulation: One of 6-MNA's main effects is how it affects sleep cycles. It works as an agonist on the brain's melatonin MT2 receptors, which helps control the sleep-wake cycle. According to research, 6-MNA can lengthen total sleep time, reduce sleep latency (the amount of time it takes to fall asleep), and enhance sleep quality. For those who have sleep disorders or have sleep patterns that are disrupted, it might be helpful.

2. Antioxidant Activity: 6-MNA exhibits antioxidant characteristics, which means it can aid in the body's efforts to combat dangerous free radicals. Free radicals are very reactive chemicals that have the potential to harm cells and play a role in a number of diseases. 6-MNA may have a preventive effect against oxidative stress and related diseases by scavenging these free radicals. This antioxidant function might benefit general health and wellbeing.

3. Potential to reduce inflammation: Several research have suggested that 6-MNA has anti-inflammatory capabilities. The inflammatory response may be modulated by inhibiting the synthesis of pro-inflammatory chemicals. This shows that 6-MNA may have therapeutic potential in diseases such rheumatoid arthritis, inflammatory bowel disease, or neuroinflammatory illnesses that are characterized by chronic inflammation.

4. Neuroprotective Effects: Early research points to the possibility that 6-MNA has neuroprotective qualities. It has been demonstrated to shield neuronal cells from neurotoxicity and oxidative stress. These results imply that 6-MNA might be investigated for its function in neurodegenerative diseases like Parkinson's or Alzheimer's. To understand its precise mechanisms of action and therapeutic potential in neuroprotection, more research is required.

6-Methoxynicotinamide Mechanism Of Action

Although the precise 6-Methoxynicotinamide (6-MNA) mode of action is not entirely established, the following mechanisms have been put forth in light of recent research:

1. Melatonin MT2 Receptor Activation: On the melatonin MT2 receptors in the brain, 6-MNA is thought to have an agonistic effect. A hormone called melatonin is essential for controlling the sleep-wake cycle. 6-MNA may have impacts on sleep regulation, such as better sleep quality and shorter sleep latency, through activating MT2 receptors. 6-MNA might synchronize and encourage the start of sleep by attaching to these receptors.

2. Antioxidant Activity: 6-MNA has shown antioxidant abilities, which could contribute to its range of effects. To lessen oxidative stress, it can scavenge free radicals and reactive oxygen species (ROS) in the body. This antioxidant activity may help explain its neuroprotective and anti-inflammatory properties by preventing cells and tissues from being harmed by excessive free radicals.

6-MNA appears to have anti-inflammatory effects, according to research. It might prevent the synthesis or release of cytokines and chemokines, two chemicals that contribute to inflammation. 6-MNA may help lessen inflammation in a number of illnesses by regulating the inflammatory response. Its anti-inflammatory properties' precise molecular mechanisms are currently being studied.

4. Modulation of Signaling Pathways: It has been demonstrated that 6-MNA influences a number of cellular signaling pathways. For instance, it has been discovered to suppress the nuclear factor-kappa B (NF-B) transcription factor, which is involved in controlling inflammatory and immunological responses. 6-MNA may affect cellular processes and contribute to its documented effects on inflammation and other physiological processes by altering various signaling pathways.

Factory Environment

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

Certificates

Packaging

Logistics Record

Except guarantee the product’s, the other most important thing is customers could receive the goods smoothly. So, Xi’an Sonwu supply all kinds of courier according to different need.

Company's Profile

Xi’an Sonwu Biotech Co . Itd is a professional Chinese manufacturer and products supplier. It was founded in 2012, and located in Hi-Tech industrial Zone Xi’an city, Shannxi province, China. It pays all attention on development, research and production of food additives, plant extract , APl and other ingredients of health care products. Our company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, Plant Extract. We sincerely believe that the premise of a great cooperation is best services and good quality. So, welcome your inquiry.

If you want to know JBSNF-000088 powder price, feel free to ocntact Xi'an Sonwu.

E-mail: sales@sonwu.com

Hot Tags: jbsnf-000088, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, raw, supply, for sale, Monobenzone Raw Powder, Flibanserin Hydrochloride, 9 ME BC Powder, Pure Pregabalin Powder, Flibanserin Powder, NMN Bulk