Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of tamoxifen citrate powder in China. We warmly welcome yuo to wholesale bulk tamoxifen citrate powder for sale here from our factory. Quality products and reasonable price are available.
What Type Of Drug Is Tamoxifen Citrate
Tamoxifen citrate powder is widely used in critical illness, especially in treating and preventing breast lesions. It belongs to a class of drugs called selective estrogen receptor modulators (SERMs). SERMs are compounds that interact with estrogen receptors in different tissues to produce agonistic or antagonistic effects. Tamoxifen citrate exerts its pharmacological effects by binding to estrogen receptors in breast tissue, especially estrogen receptor alpha (ERα). This binding inhibits the action of estrogen, preventing it from stimulating breast cell proliferation. It is commonly used to treat early and late breast lesions in premenopausal and postmenopausal women. Tamoxifen is particularly effective against specific subtypes of breast disease that express estrogen receptors, such as estrogen receptor-positive (ER+) breast lesions.
In addition to treating breast disease, tamoxifen citrate has other medical uses. It is sometimes used to reduce the risk of breast disease in high-risk groups, such as those with a strong family history or specific gene mutations. It is called chemoprevention or risk reduction therapy. It can also be used for other conditions. For example, it may be used in men with gynecomastia, a condition characterized by the development of male breast tissue. In these cases, the anti-estrogenic effects of tamoxifen can help reduce breast size. In addition, tamoxifen has been explored for its potential to preserve fertility and treat infertility. It is used in women undergoing treatment for diseased diseases to protect the ovaries from the toxic effects of chemotherapy and thereby keep their fertility. It can also be used for ovulation induction therapy in anovulatory infertile women. So tamoxifen powder is increasingly widely used; if you are interested in pure tamoxifen powder, please contact Xi'an Sonwu.

Certificate Of Analysis
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ANALYSIS |
SPECIFICATION |
RUSULT |
|
Assay |
99.00%HPLC |
99.18% |
|
Appearance |
Off-white crystalline powder |
Complies |
|
Solubility |
The solubility in water is low, about 0.2 mg/mL. Better dissolved in ethanol, acetone, dichloromethane, chloroform, etc. |
Complies |
|
Loss on drying |
≤0.5% |
0.13% |
|
Heavy metals |
||
|
Lead |
≤0.5 ppm (mg/kg) |
Complies |
|
Arsenic |
≤0.5 ppm (mg/kg) |
Complies |
|
Mercury |
≤0.5 ppm (mg/kg) |
Complies |
|
Cadmium |
≤0.5 ppm (mg/kg) |
Complies |
|
Microbial control |
||
|
Total bacterial count |
≤1000CFU/g |
Complies |
|
Molds and yeast |
≤1000CFU/g |
Complies |
|
E. coli |
Not detected |
Not detected |
|
Salmonella |
Not detected |
Not detected |
|
Conclusion |
This batch product complies with international standards |
|
Best Place To Buy Tamoxifen
Xi'an Sonwu Biotech Co. Ltd. is a manufacturer and distributor with more than ten years of experience. It has extensive and stable cooperation with countries worldwide in the Americas, Asia, Europe, and Oceania. Xi'an Sonwu has always insisted on product quality first; serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from the selection of raw materials, and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need any API raw materials, please get in touch with Xi'an Sonwu.
Xi'an Sonwu ultimately ensures the product's quality and offers a sample for your test. Here is the quantity.
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Tamoxifen Form |
Sample Amount |
MOQ |
|
Powder |
50g |
100g |
Customers's Good Comment

What Is The Primary Target Of Tamoxifen
The main target of tamoxifen is the estrogen receptor (ER) in breast tissue. Tamoxifen binds to and antagonizes estrogen receptors as a selective estrogen receptor modulator. There are two subtypes of estrogen receptors: estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). In breast tissue, tamoxifen primarily targets estrogen receptor alpha (ERα). By binding to ERα, tamoxifen competes with estrogen for binding to the receptor. In hormone-sensitive, (estrogen receptor-positive or ER+) breast disease, diseased cell growth is primarily driven by estrogen. By binding to estrogen receptors, tamoxifen prevents estrogen from binding and activates these receptors. It blocks the stimulating effects of estrogen on the growth and proliferation of breast disease cells. By acting as an antagonist of estrogen receptors in breast tissue, tamoxifen helps inhibit the growth of ER+ breast diseases and reduces the risk of significant disease recurrence. It can be used in premenopausal and postmenopausal women with ER+ breast disease.
Tamoxifen may affect different tissues differently. In some tissues, such as the uterus, tamoxifen can act as a partial agonist. It activates ERα signaling to produce estrogen-like effects in these tissues. In addition, tamoxifen can be metabolized by the liver to its active metabolite endoxifen. Edoxifene binds ERα with a higher affinity and for a longer duration than tamoxifen itself. This combination contributes significantly to the therapeutic effect of tamoxifen, as it further inhibits estrogen signaling and promotes antiestrogenic activity in breast tissue.

What Is Tamoxifen Used For
Tamoxifen citrate powder has various uses, primarily for treating and preventing breast disease.
1. Breast disease treatment
Tamoxifen is widely used in the treatment of early and advanced breast disease. Specifically, it is effective against estrogen receptor-positive (ER+) breast disease, dependent on estrogen for growth. Tamoxifen acts as an antagonist by blocking estrogen receptors in breast tissue, thereby preventing estrogen from stimulating the diseased cells.
2. Breast disease prevention
Tamoxifen can be used as a preventive measure in women at high risk of breast disease. It has significantly reduced the risk of invasive and non-invasive breast disease in high-risk individuals. It includes women with a strong family history of breast disease or mutations in specific genes, such as BRCA1 and BRCA2.

3. Gynecomastia treatment
Tamoxifen is also used to treat gynecomastia, which, as the name suggests, is characterized by enlarged breast tissue in men. In some cases, hormonal imbalances or the use of certain medications may cause gynecomastia. The tamoxifen's anti-estrogen properties help counteract estrogen's effects on male breast tissue, reducing swelling and tenderness.
4. Fertility preservation
Sometimes, tamoxifen may preserve fertility in women undergoing treatment for a significant medical condition. Specific chemotherapy regimens can cause damage to the ovaries and may affect future fertility. Tamoxifen is combined with other medications to help stimulate the ovaries and promote the production of viable eggs for future use.

5. Infertility treatment
Tamoxifen has been studied for its potential role in treating infertility in women with specific hormone imbalances, such as polycystic ovary syndrome (PCOS). It may help induce ovulation by modulating estrogen receptors and promoting follicular development.
What Are The Worst Side Effects Of Tamoxifen
While tamoxifen is generally well-tolerated, it may have some of the potential worst side effects of tamoxifen include:
Increased risk of blood clots: Tamoxifen increases the risk of blood clots, including pulmonary embolism (PE) and deep vein thrombosis (DVT). These are severe conditions that can be life-threatening if left untreated.

Hot flashes: Hot flashes are a common side effect of tamoxifen. They involve sudden intense warmth, often accompanied by sweating and flushing. Severe hot flashes can seriously affect a person's quality of life.
Mood changes and depression: Some individuals taking tamoxifen may experience mood swings, depression, or anxiety. Monitoring and discussing mood or mental health changes with a healthcare professional is essential.
Bone loss and increased risk of osteoporosis: Long-term tamoxifen use may lead to bone loss in some individuals, increasing the risk of osteoporosis and fractures.
Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

Certificate

Package

Logistics

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ
The tamoxifen dosage can vary depending on the specific condition being treated, the individual's age, overall health, and other factors. It is vital to follow the recommended dosage a healthcare professional provides and consult them before making any changes. That being said, here are the general guidelines for tamoxifen dosage in different populations:
Breast disease treatment:
For early-stage breast disease: The standard dosage is usually 20 mg of tamoxifen once daily for 5 to 10 years. The exact time can vary depending on various factors, including the stage and characteristics of the disease.
For advanced or metastatic breast disease: The dosage may be increased to 20-40 mg of tamoxifen once or twice daily. In some cases, higher dosages may be prescribed.
Breast disease risk reduction:
The recommended breast disease risk reduction dosage is typically 20 mg of tamoxifen taken once daily for five years or as a healthcare professional prescribes.
Gynecomastia in men:
The dosage for gynecomastia treatment in men may vary. It can range from 10-20 mg of tamoxifen taken once daily for a period specified by a healthcare provider. If you have any questions or concerns about paxillin sodium, it is best to consult with a doctor who can provide personalized guidance and address your specific needs.
If you want to know to get the tamoxifen price, you can contact Xi'an Sonwu. Click the email then you get high-quality tamoxifen citrate powder.
Email: sales@sonwu.com
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