How much do you know about the whitening principle of decapeptide-12?
Decapeptide-12.The key to whitening skin lies in the ability of melanocytes to produce melanin. Melanocytes are distributed among the cells in the basal layer of the human epidermis. The tyrosinase contained in them can oxidize tyrosine into sugar, which then undergoes a series of excretion processes and finally turns into melanin.
The more melanin is converted, the darker the skin; on the contrary, the whiter the skin. Tyrosinase has a unique two-way catalytic effect and is an important enzyme for the production of melanin in organisms. It is closely related to human aging.
Its abnormal and excessive expression can cause pigmentation diseases in the body. Tyrosinase inhibitors can treat common pigmentation skin diseases such as chloasma, melasma, and age spots.
Arbutin, vitamin C compounds, kojic acid and compounds, green tea extract, licorice extract and other Chinese herbal extracts in the popular whitening cosmetics on the market are all tyrosinase inhibitors, which mainly inhibit the activity of tyrosinase to inhibit melanin production, thereby giving full play to the whitening effect.
Decapeptide-12 is a revolutionary peptide technology developed by dermatology researchers at Stanford University to improve the appearance of hyperpigmentation, age spots, sun spots, post-inflammatory pigmentation, uneven skin tone and photodamage.
Our skin color is mainly determined by two reasons.
1.genetic factors.
Genetic genes determine the various constitutions of our body, such as the size of the eyes, facial features, etc.
Similarly, skin color is also determined by genetic genes. You will find that the part of the skin that has been wrapped under clothes since childhood is the whitest compared to other places. This is also the original skin color determined by genes.
2. External factors
In addition to internal factors determined by genes, the external environment is also an important factor affecting skin color. The most direct one is ultraviolet radiation.
Ultraviolet rays activate tyrosinase, and the synthesis of pigments is closely related to tyrosinase.
Melanocytes are distributed between the cells of the basal layer of the human epidermis. The tyrosinase contained in them can oxidize tyrosine into polysaccharides, which then undergo a series of metabolic processes and finally produce melanin.
So what role does the decapeptide-12 developed by Stanford University play in the study of skin brightening?
Decapeptide-12 is a new synthetic oligopeptide, which contains tyrosine, arginine and serine in its sequence. These amino acids have strong inhibitory effects on the activity of tyrosinase. Therefore, decapeptide-12 can inhibit the activity of tyrosinase, thereby effectively reducing the synthesis of melanin.
According to research by Anan Abu Ubeid and others, compared with hydroquinone, decapeptide-12 has a stronger performance in inhibiting intracellular tyrosinase and is non-toxic.
A study by Kassim et al. showed that the improvement of hemifacial melasma with decapeptide-12 was more than 50% compared with patients who did not respond to 6 months of hydroquinone-retinoic acid-steroid combination cream.
Decapeptide-12 Powder, also known as Caprooyl Tetrapeptide-12, is a synthetic peptide ingredient commonly used in skincare products. it is intended to treat various skin conditions and is known for its potential cosmetic benefits.lt is often used in skincare formulations due to its purported skin brightening, anti-aging, and overall skin tone improvement properties.It is thought to help even skin tone and lessen the visibility of discoloration or dark patches.
lt is commonly found in various products such as serums,creams,and lotions designed to target hyperpigmentation, uneven skin tone,and age spots.The peptide is believed to have skin-brightening properties because it prevent melanin synthesis,the pigment that determines skin tone. it also supports the reduction of skin inflammation and provides antioxidant benefits.
1.Anti-aging Effects: This peptide may improve skin suppleness and stimulate the creation of collagen to help fight the indications of aging.
2.Skin Brightening:it can help brighten and even tone the skin.
3.Evening Skin Tone: it aids in balancing skin tone by targeting areas of uneven pigmentation or redness.
4.Moisturizing and Nourishing:Decapeptide-12 can support skin hydration,helping maintain the skin's moisture levels and enhancing overall skin health.
By incorporating Decapeptide-12 into skincare formulations, manufacturers aim to provide users with products that target multiple skin concerns, includcing brightening, anti-aging, and skin tone improvement, resulting in healthier and more youthful-looking skin.