Orotic Acid Lithium Salt Monohydrate

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of orotic acid lithium salt monohydrate in China. We warmly welcome yuo to wholesale bulk orotic acid lithium salt monohydrate for sale here from our factory. Quality products and reasonable price are available.

Orotic Acid Supplement
Orotic acid lithium salt monohydrate is obtained by condensing diethyl oxalate and ethyl acetate into diethyl butyrate, which is cyclized with urea and then hydrolyzed. It is used in medicine to treat jaundice and general liver dysfunction. Lithium orotate is a form of the lithium salt of orotic acid, which has a role in targeted anti-osteosarcoma therapy. Orotic acid is a natural substance that your body produces naturally through gut flora. This acid is also known as vitamin B13. Although not a proper vitamin, it has been added to the diets of laboratory animals as a supplement to help promote heart health and has been shown to have vitamin-like benefits. Lithium, on the other hand, belongs to the alkali metals of the chemical elements, which are highly reactive and explosive, although it is the least reactive alkali metal. Lithium occurs naturally only in compositions, usually as ions in nature, such as lithium carbonate. After research, lithium has been officially introduced into psychiatric clinics to treat mania. However, lithium salts have specific toxic and side effects, which limits their widespread use.
A lithium orotate dietary supplement can help with cluster and migraine headaches. It is currently being studied for its stimulating effect on leukopoiesis in diabetics and autoimmune diseases. If you are interested in raw lithium orotate, please get in touch with Xi'an Sonwu.
 

Certificate Of Analysis

Customers' Good Comment

Where To Buy Lithium Orotate
Xi'an Sonwu is a manufacturer and distributor with more than ten years of experience. It has extensive and stable cooperation with countries in the Americas, Asia, Europe, and Oceania worldwide. Xi'an Sonwu has always insisted on product quality first. Serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from the selection of raw materials, and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need plant extract powder or capsules, don't hesitate to contact Xi'an Sonwu.
Xi'an Sonwu ultimately ensures product quality and also offers samples. Here is the quantity.

Customers' Good Comment

OEM Service
Xi'an Sonwu can supply high-quality powder and capsules.
So any customers could customize capsules and the following item.
1. Customized capsules shells (size, color, material)
2. Customized bottles(size, color, material, style)
3. Customized packaging(vacuum foil packaging, box, drum)
4. Customized label(paint film, matte film, optical mask)

Lithium Orotate Uses
1. For the preparation of anti-osteosarcoma composition
The most critical role in lithium orotate is lithium. Experiments have shown that lithium preparations have significant anti-osteosarcoma effects in vivo and in vitro, which may be achieved by phosphorylating GSK-3β and inhibiting its function. It is a potential targeted therapy for osteosarcoma combined with classic chemotherapy drugs such as doxorubicin to enhance its killing effect on sarcoma significantly. Lithium salts can be lithium chloride, carbonate, sulfate, citrate, orotate, and other pharmaceutically available or used lithium salts.
When lithium preparations are used for targeted osteosarcoma therapy, the following treatment plan is usually adopted: add isotonic regulators such as NaCl, glucose, etc., and prepare powder injections or injections. It can also use orally, but the dosage should double. It can also mix with other anti-tumor drugs, such as compounding with doxorubicin, which can achieve enhanced or synergistic therapeutic effects. Xi'an Sonwu can provide you with this lithium orotate complex.

2. For the preparation of CNS diseases
The CNS is the central part of the nervous system and consists of the cranial ganglia, nerve cords or brain and spinal cord, and the connecting components between them. It may be caused by system aging or severe damage. In the course of treatment of a CNS disease which involves contacting the in vitro differentiated choroid plexus cells in one or more capsules with a choroid plexus-inducing agent, either concurrently with or after administration, comprising a group selected from the group consisting of One or more reagents:
Wnt signaling pathway agonists
GSK3β inhibitor
beta-catenin activator
Antioxidants and (e) 1,25-dihydroxy vitamin D3.
The GSK3β inhibitor is selected from SB-216763, lithium chloride, carbonate, citrate, orotate, and the like. As such, it may help treat Huntington's, Alzheimer's, Parkinson's, and dementia.

3. For brain relaxation
Under the stress of our current life, our brain needs more nutrients to fight stress. The three most important substances are iodine, lithium, and lithium orotate, which can effectively prevent nutritional deficiencies. Lithium orotate helps the brain produce more serotonin and prevents dopamine levels from getting too high.
Some users find lithium orotate calming and stress-relieving by replenishing the brain with the minerals it needs.
From a medical point of view, lithium can prevent premature death of brain cells due to long-term exposure to artificial sweeteners such as corn syrup and monosodium glutamate. Lithium also stores and increases gray matter in the brain and is a drug used to treat bipolar disorder. People with bipolar disorder often take high doses of lithium carbonate. Low lithium orotate doses can safely improve your brain health and increase myelination. Studies have shown that lithium induces autophagy in the brain and enhances the breakdown and clearance of proteins that contribute to neuropsychiatric and neurodegenerative diseases.

How Does Lithium Orotate Work
Orotic acid lithium salt monohydrate is a naturally occurring mineral, so how does it work?
It acts on many different pathways in the brain.
Lithium stimulates the production of neural stem cells, and brain imaging shows it increases the volume of the amygdala and hippocampus and neurogenesis.
One of the essential effects of lithium is inhibiting the compound GSK-3β. This inhibition leads to more brain-derived neurotrophic factor (BDNF), a significant factor in the production of new neurons. GSK-3β is involved in apoptosis, or programmed cell death, so reducing it ensures your brain doesn't destroy healthy neurons. Inhibition of GSK-3β also acts as an antidepressant.
Lithium orotate has been shown to alter glutamate receptors' inward and outward currents (specifically GluR3) without changing the reversal potential. The central excitatory neurotransmitter glutamate in the brain is required for many cognitive functions. However, too much glutamate can damage neurons and cause cognitive problems. Fortunately, lithium can control glutamate levels, protect the brain long-term and improve mood and mental function. Lithium has been found to have a dual effect on glutamate receptors by maintaining a stable and healthy level of glutamate activity in cells. It has been hypothesized that too much glutamate in the spaces between neurons causes the symptoms of mania.
Li+ exerts its effects by interacting with the transport of monovalent or divalent cations in neurons. Another mechanism by which lithium may also help regulate mood is called inositol monophosphatase.

Factory
1. Xi'an Sonwu Biotech Co., Ltd has an orderly, clean, and tidy production department and its factory to produce, manufacture, and store products, so there is sufficient inventory. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu Biotech Co., Ltd has strict requirements on staffing from production and testing to sales. Make sure to provide uncompromising data support and after-sales service for each product.

Certificate

Packing

Logistics

Besides guaranteeing the product, Xi'an Sonwu also assists customers in receiving the goods safely. So, Xi'an Sonwu can supply different couriers according to customers' needs.

FAQ
Although lithium orotate is a good brain tonic, it was confused with the prescription drug potassium carbonate for a long time. Some of the latter's toxic side effects were attributed to lithium orotate. For some people, lithium orotate is effective in minimal doses. So remember, don't overdose, and follow the doctor's advice.
The safe range of lithium orotate is 1 to 5 mg. According to human digestion and absorption laws, supplementing lithium orotate with about 1 to 5 mg is a relatively safe dose.
If you want to know lithium orotate price, you can contact Xi'an Sonwu. Click the email then you get high-quality orotic acid lithium salt monohydrate.
Email: sales@sonwu.com

Hot Tags: orotic acid lithium salt monohydrate, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, raw, supply, for sale, Glutathione Bulk, NMN, API, Agomelatine Powder, NMN, Pure Pregabalin Powder