Nicotinamide Riboside Chloride Powder

What is nicotinamide riboside chloride?

Nicotinamide Riboside Chloride powder is derived from Nicotinamide Riboside Chloride, which is actually an alternative form of Vitamin B3, often referred to as niacin. Nicotinamide Riboside Chloride may also be called niagen or shortened as NRC. Once ingested in the body, it will be converted into Nicotinamide Adenine Dinucleotide or NAD+. NAD+ is one of the most important enzymes in human physiology. It is responsible for fueling a number of key biological processes including the conversion of food into energy and fortifying the defense systems found within each cell. The enzyme may also be crucial in repairing damaged DNA and can have an additional positive effect in promoting healthy aging. The body can produce its own NAD+ enzyme easily without supplementation. The sad part is that, as people continue to age, the amount of NAD+ produced by the body declines. In essence, older people will have lower levels of this important enzyme compared to younger ones. This is where supplementation becomes very important. Using Nicotinamide Riboside Chloride supplements to enhance NAD+ levels, especially among older people, may offer a number of incredible benefits. Xi'an Sonwu, as a professional manufacturer and supplier of nicotinamide riboside chloride, can provide high quality  products with attractive price. If you need it, welcome to contact Xi'an Sonwu.

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What is nicotinamide riboside chloride good for?

The benefits of NRC can be viewed in relation to the role NAD+ plays in the body. This is because supplementation of NRC will raise NAD+ levels and in turn this important coenzyme will deliver the following benefits:

1. Easily converted into NAD+

NAD is a biological proper noun whose Chinese name is nicotinamide adenine dinucleotide, abbreviated as coenzyme I. It is the most important coenzyme of oxidoreductase in the metabolic process of organisms. In mammals, there are two states, oxidized (NAD+) and reduced (NADH), and participate in thousands of redox reactions. That is, the term NAD is used to collectively refer to two different forms of NAD: NAD+ and NADH. NAD+ is a coenzyme, or helper molecule, that takes part in many biological reactions. While it's essential for optimal health, research shows that NAD+ levels continue to fall with age. Low NAD+ levels are linked to poor aging and a variety of harmful diseases. One way to raise NAD+ levels is to consume NAD+ precursors — the building blocks of NAD+ — such as nicotinamide riboside. Animal studies show that nicotinamide riboside raises blood NAD+ levels by up to 2.7 times. What's more, it's more readily used by the body than other NAD+ precursors.

2. Activating enzymes that may promote healthy aging

NRC helps increase NAD+ levels in the body. In response, NAD+ activates certain enzymes that may promote healthy aging.

One group is sirtuins, which appear to improve lifespan and overall health in animals. Studies indicate that sirtuins may repair damaged DNA, boost stress resistance, reduce inflammation and offer other benefits that promote healthy aging. They are also responsible for the lifespan-extending benefits of calorie restriction.

Another group is Poly (ADP-Ribose) polymerases (PARPs), which repair damaged DNA. Studies link higher PARP activity to less DNA damage and a longer lifespan.

3. Improving cell defense mechanism in the brain

NAD+ can also protect brain cells from irregular degeneration, especially with aging. Some studies show that NAD+ may control the production of a protein called PGC-1-alpha, a protein that appears to help protect cells against oxidative stress and impaired mitochondrial function.The protein is significantly vital in protecting cells against oxidative stress. It may also improve and repair mitochondrial functions in brain cells, leading to better cognitive health.

There are also dozens of research studies linking oxidative stress and damaged mitochondrial functions in brain cells with age-related brain disorders such as Alzheimer's, Parkinson's and others. The action of NAD+ in reducing these processes could significantly reduce the risk of Alzheimer's and other degenerative brain diseases. The effectiveness of NAD+ in this is actually very high. In some animal studies where mice with Alzheimer's were treated with Nicotinamide Riboside Chloride, the levels of PGC-1-alpha in the brain increased by between 50 and 70%. By the end of the studies, the mice treated with NR showed significant improvement in memory-based tasks.

4. May help with heart problems

The risk of heart failure increases significantly with aging. Heart failure is also a very common issue in fact it is the number one cause of death globally. It can cause blood vessels like your aorta to become thicker, stiffer and less flexible. Such changes can raise blood pressure levels and make your heart work harder. Overall heart health is dependent on many factors though including proper diet and exercise. But there are certain things that may lower the risk. Increased production of NAD+ is one of these things.

Test studies done on animals found that increased production of NAD+ helped to reverse potentially dangerous changes in blood arteries caused by aging. In some human-based studies, high levels of NAD+ led to the reduction of stiffness in the aorta. NAD+ was also reported to lower the potential risk of systolic blood pressure. This simply means that there is real potential of using Nicotinamide Riboside Chloride as a possible supplement in reducing the risk of heart disease. 

How does nicotinamide riboside chloride work?

Nicotinamide Riboside Chloride powder will be converted into NAD+, once ingested in the body. Therefore, the supplement of NRC will increase the level of NAD+. NAD+, or nicotinamide adenine dinucleotide, is a coenzyme found in all of our cells. It is essential for the metabolic processing of nutrients. As it's a coenzyme ("co-" as in cooperate), it also binds with other proteins to help provide a variety of benefits such as DNA repair and cell repair. So, How does NAD+ work?

The truth is that NAD doesn't provide any direct benefit to any part of your body. It simply helps your cells work better. Here's how:

As we mentioned before, NAD is a "helper" coenzyme. It works by transferring electrons from transporting electrons from one molecule to another within cells to carry out all sorts of reactions and processes. So, you can think of each NAD coenzyme as a tiny shuttle bus responsible for taking electrons to work inside the mitochondria (the part of the cell responsible for metabolizing nutrients).

The more shuttle buses you have, the more electrons get delivered to the mitochondria. These electrons fuel chemical reactions that power the cell and keep the body healthy. In order to pick up electrons and move them from place to place, NAD triggers other reactions which keep the cell buzzing with life. When there aren't a lot of NAD shuttle buses, fewer nutrients get processed by the mitochondria, and fewer reactions happen within the cell. As a result, the cells begin to age and die. 

Is nicotinamide riboside chloride safe? 

NRC bulk is a very safe supplement to use but just like any product, it has several potential side effects that you should be aware of. In some human studies, test subjects were given between 1000 milligrams and 2000 milligrams of Nicotinamide Riboside Chloride and did not witness any harmful effects whatsoever. So far, manufacturers of NRC recommend between 200 mgs and 300 mgs of the product a day. Despite this safety record, nicotinamide riboside chloride may have a few side effects to keep in mind. First, some people have reported feeling nauseated after using the product. In other cases, patients felt fatigued and headaches as a result of nicotinamide riboside chloride. It is also not uncommon to experience digestive issues including stomach discomfort and diarrhea.

However, the severity of side effects is very different from one individual to another. Some people do not even experience these effects at all. If you are on any other medications, talk to your doctor first before using it.

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1. Xi'an Sonwu has been engaged in import-export for over 10 years with rich experience in development, research and production of API, plant extract, food additives, and other raw ingredients of health care products;

2. Xi'an Sonwu has a professional team with clear division of labor;

3. Products are tested by third parties;

4. OEM service is available.

If you're interested in and want to buy Nicotinamide Riboside Chloride Powder, please contact Xi'an Sonwu.

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