Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 5-fluorocytosine powder in China. We warmly welcome yuo to wholesale bulk 5-fluorocytosine powder for sale here from our factory. Quality products and reasonable price are available.
What is 5-Fluorocytosine
5-Fluorocytosine Powder is a synthetic compound used in medicine. It is an antimicrobial agent and antifungal drug that is converted into 5-fluorouracil (5-FU) in the body. 5-fluorocytosine is primarily used in combination with other antifungal medications for the treatment of certain fungal infections.
COA
|
Analysis |
Specification |
Result |
|
Aρpearance |
White Powder |
Conforms |
|
Odor |
Characteristic |
Conforms |
|
Assay |
≥99% |
99.17% |
|
Mesh Size |
100% pass 80 mesh |
Conforms |
|
Loss on drying |
≤5.0% |
2.65% |
|
Ash |
≤5.0% |
2.85% |
|
Heavy Metals |
≤10ppm |
Conforms |
|
As |
≤1ppm |
Conforms |
|
Pb |
≤2ppm |
Conforms |
|
Hg |
≤0.1ppm |
Conforms |
|
Cd |
≤1ppm |
Conforms |
|
Microbiological |
||
|
Total Plate Count |
≤1000cfu/g |
Conforms |
|
Yeast & Mold |
≤100cfu/g |
Conforms |
|
Salmonella |
Negative |
Negative |
|
E.Coli |
Negative |
Negative |
|
Residue pesticide |
Negative |
Negative |
|
Conclusion |
Conforming to Enterprise Standard |
|
Where To Buy 5-Fluorocytosine
Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce costs to the maximum extent, and then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you want to buy 5-fluorocytosine.
Xi'an Sonwu completely makes sure of the product’s quality, so samples can be supplied. Here is the quantity.
|
Form |
Sample Amount |
The Minimum of Quantity |
|
Powder |
50g |
100g |
Customers’s Good Comment
What Is 5-FC Used For
5-Fluorocytosine, also known as 5-FC or flucytosine, is an antifungal medication that is primarily used for the treatment of fungal infections, particularly those caused by certain species of Candida and Cryptococcus. Here are some key points:
1. Systemic Fungal Infections: 5-Fluorocytosine Powder is often used in combination with other antifungal medications to treat systemic fungal infections. It has demonstrated effectiveness against various strains of Candida and Cryptococcus, including those that are resistant to other antifungal drugs.
2. Cryptococcal Meningitis: 5-FC is considered an essential component of the initial treatment regimen for cryptococcal meningitis, a severe fungal infection that affects the membranes surrounding the brain and spinal cord. It is typically used in combination with amphotericin B or fluconazole.
3. Candidiasis: In certain cases of invasive candidiasis, when the infection is not adequately controlled with other antifungal agents, it may be added to the treatment regimen to enhance efficacy.
It's important to note that 5-FC is generally administered in combination with other antifungal medications rather than used alone. This combination therapy helps to prevent the development of resistance and improves treatment outcomes.
The specific use should be determined by a healthcare professional who will consider factors such as the type and severity of the fungal infection, patient's medical history, and potential drug interactions.
What Is The Mechanism Of 5-FC
The mechanism of action involves its conversion into an active form within fungal cells. Once inside the fungal cell, It is converted by the enzyme cytosine deaminase to 5-fluorouracil (5-FU), which is further metabolized into other active metabolites.
These active metabolites interfere with fungal RNA and protein synthesis by inhibiting the synthesis of fungal DNA and RNA. 5-FU and its metabolites are incorporated into the fungal RNA and disrupt normal cellular processes, ultimately leading to the inhibition of fungal growth and replication.
Additionally, It can also interfere with the conversion of uracil to thymidine, which is necessary for DNA synthesis in fungal cells. This disruption further contributes to the antifungal activity of 5-FC.
It's worth noting that 5-FC's mechanism of action is selective to fungal cells because the conversion of 5-FC to its active form is primarily facilitated by cytosine deaminase, which is more abundant in fungal cells than in human cells. This selective activation helps minimize the impact on human cells, reducing the potential for toxicity.
However, it's important to mention that the development of resistance to 5-FC can occur due to mutations or alterations in the enzymes responsible for its activation or uptake by fungal cells. Therefore, It is often used in combination with other antifungal agents to increase effectiveness and reduce the risk of resistance development.
What Are The Side Effects
Like any medication, 5-Fluorocytosine can cause side effects. Here are some potential side effects that have been reported:
1. Gastrointestinal Effects: Common gastrointestinal side effects may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. These symptoms are generally mild and resolve upon completion of treatment.
2. Bone Marrow Suppression: It can affect the bone marrow's ability to produce blood cells, which makes a decrease in white blood cells, red blood cells, and platelets. This can increase the risk of infections, anemia, and bleeding. Regular monitoring of blood cell counts is typically recommended during treatment.
3. Hepatotoxicity: Rare cases of liver damage, including elevated liver enzymes, hepatitis, and liver failure, have been reported with the use of 5-FC. Monitoring of liver function is important during treatment, especially for individuals with pre-existing liver disease.
4. Skin Reactions: Skin rash, itching, and allergic reactions may occur in some individuals. Even some serious skin reactions such as toxic epidermal necrolysis are rare but can be life-threatening. Seek medical attention if you experience severe skin reactions.
5. Renal Impairment: High doses or prolonged treatment duration may rarely result in kidney problems. Monitoring of kidney function is typically recommended, especially in patients with pre-existing renal impairment.
It's important to note that this is not an exhaustive list of all possible side effects. Some individuals may experience other adverse reactions. If you are prescribed 5-FC and experience any concerning or persistent side effects, it is crucial to contact your healthcare provider for guidance.
Your healthcare provider is the best resource to discuss the potential risks and benefits based on your specific medical condition and individual factors.
Is Flucytosine Same As Fluconazole
No, flucytosine (also known as 5-fluorocytosine or 5-FC) is not the same as fluconazole. While both medications are used in the treatment of fungal infections, they belong to different classes of antifungal drugs and have distinct mechanisms of action.
Flucytosine is an antifungal medication that inhibits the synthesis of fungal DNA and RNA. It is mainly used in combination with other antifungal agents, such as amphotericin B, to treat systemic fungal infections caused by certain species of Candida and Cryptococcus.
On the other hand, fluconazole belongs to a class of antifungal drugs known as azoles. It works by restraining the synthesis of ergosterol, a component of the fungal cell membrane. It is commonly used for the treatment of various fungal infections, including vaginal yeast infections, oral thrush, and systemic candidiasis.
While both flucytosine and fluconazole are used in the management of fungal infections, they have different spectrums of activity, mechanisms of action, and specific indications. The choice of medication depends on the type and severity of the fungal infection, as well as other individual patient factors. It's important to consult with a healthcare professional for appropriate diagnosis and treatment recommendations.
How Do You Administer Flucytosine
Flucytosine (5-FC) is usually administered orally in the form of capsules or tablets. It is important to follow the specific instructions provided by your healthcare provider or as indicated on the medication label. Here are some general guidelines for administering flucytosine:
1. Dosage: The dosage of flucytosine prescribed deponds on various factors, including the type and severity of the fungal infection, your age, weight, and overall health condition. Take the medication exactly as prescribed by your healthcare provider, and do not adjust the dosage without their guidance.
2. Timing: Flucytosine is typically taken multiple times a day at evenly spaced intervals to maintain a consistent level of the medication in the body. Follow the prescribed dosing schedule, and try to take the medication at the same times each day for optimal effectiveness.
3. Food: Flucytosine can generally be taken with or without food. However, it is recommended to follow any specific instructions given by your healthcare provider or medication label regarding food intake. Some individuals may find it helpful to take flucytosine with food to minimize stomach upset.
4. Swallowing: Swallow the flucytosine capsules or tablets whole with a full glass of water. Do not chew, crush, or break them unless instructed otherwise. If you have difficulty swallowing, please consult your healthcare provider for alternative dosage forms or methods of administration.
5. Duration of Treatment: The duration of flucytosine treatment will depend on the specific fungal infection being treated. It is crucial to complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished. Stopping the medication prematurely can lead to an incomplete eradication of the infection and potential relapse.
Always consult your healthcare provider or pharmacist for precise instructions on how to administer flucytosine based on your individual circumstances. They can provide you with the most accurate and up-to-date information regarding dosage, administration, and any specific precautions or considerations.
How Long Is The Treatment For Flucytosine
The duration of flucytosine (5-FC) treatment can vary depending on the specific fungal infection being treated, its severity, and individual patient factors. Generally, the treatment duration with flucytosine can range from a few weeks to several months. It is important to follow the exact duration recommended by your healthcare provider.
For some fungal infections, flucytosine may be used as part of a combination therapy with other antifungal medications. In such cases, the treatment duration will depend on the overall treatment plan and the specific combination of medications prescribed.
To determine the appropriate treatment duration, your healthcare provider will consider factors such as the type of fungal infection, its location and extent, your overall health condition, and how well you respond to the treatment. They may also perform follow-up tests or assessments to monitor the progress of the infection and make any necessary adjustments to the duration or regimen.
It is crucial to complete the full course of flucytosine treatment as prescribed, even if your symptoms improve before the medication is finished. Stopping the treatment prematurely can lead to incomplete eradication of the infection, increasing the risk of recurrence or development of drug resistance.
Always consult with your doctor for specific guidance regarding the duration of flucytosine treatment based on your individual circumstances and the nature of your fungal infection. They will provide you with personalized recommendations and ensure that the treatment plan is tailored to your needs.
Should Flucytosine Be Taken Before Or After Food
Flucytosine (5-FC) can generally be taken with or without food. However, it is recommended to follow any specific instructions provided by your healthcare provider or indicated on the medication label regarding food intake.
Taking flucytosine with food may help reduce the potential for stomach upset or gastrointestinal side effects. If you experience any stomach discomfort when taking flucytosine on an empty stomach, you may consider taking it with a meal or a snack. This can help minimize the risk of stomach irritation.
On the other hand, if your healthcare provider specifically advises taking flucytosine on an empty stomach for optimal absorption or efficacy, it is important to follow their instructions strictly.
To ensure you take flucytosine correctly, it is recommended to consult your healthcare provider or pharmacist for precise instructions on whether to take it before or after food based on your individual circumstances. They can provide you with the most accurate and up-to-date information regarding the administration of flucytosine and any specific considerations related to food intake. It's essential to follow their guidance for the best results.
Factory
1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.
2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.
Certificate
Package
Logistics Update
In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi’an Sonwu supplies all kinds of couriers according to different needs.
Company's Profile
Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry.
And if you want to know the 5-Fluorocytosine Powder price, please contact XI’an Sonwu.
Email: sales@sonwu.com
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