Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of noopept powder in China. We warmly welcome yuo to wholesale bulk noopept powder for sale here from our factory. Quality products and reasonable price are available.
Introduction
Noopept powder is a nootropic supplement which is quite popular among students and professionals, who use it as a general multipurpose nootropic agent taken in daily doses. Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111) is often included in the racetam-family of nootropic compounds. But it is not a true "racetam" because it does not have a 2-oxo-pyrrolidine nucleus. Noopept was developed in Russia where it is called Ноопепт or GVS-111. Russian-based pharmaceutical company JSC LEKKO Pharmaceuticals synthesized it in 1996 based off the endogenous neuropeptide cycloprolylglycine (CPG). Just like with other popular nootropics, noopept benefits people by enhancing cognitive function, improving memory consolidation and recall, reducing brain fog, and helping to regulate moods. Xi'an Sonwu, as noopept supplier, can provide high quality powder with attractive price. If you need noopept, please contact Xi'an Sonwu.
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Specification
ANALYSIS | SPECIFICATION | RUSULT |
Description | Almost White Crystal Powder | Conforms |
Assay | ≥99.5% | 99.88% |
Odor & Taste | Characteristic | Conforms |
Identification | Positive | Conforms |
Melting Point | 97-98% | 97.58% |
PH | 2.3-2.7 | 2.5 |
Loss on Drying | ≤0.1% | 0.038% |
Residue On Ignition | ≤0.5% | 0.15% |
Relative Material | ≤0.1% | 0.07% |
Heavy Metal (As, Pb) | ≤20ppm | Conforms |
Conclusion | Conforming to Enterprise Standard | |
How does Noopept work?
Noopept powder boosts brain health and function in several ways. But two in particular stand out.
1. Noopept modulates AMPA and NMDA receptors and acetylcholine (ACh) transmission.
Noopept boosts the level of cycloprolylglycine (CPG) in the brain. CPG is a dipeptide consisting of proline and glycine which acts as a modulator of acetylcholine transmission, and AMPA and NMDA receptors. When brain cells are starved of oxygen, glutamate which is your brain's primary excitatory neurotransmitter, does not work efficiently with neuroreceptors. The result can be a toxic buildup of glutamate within brain cells. Causing neuron damage and ultimately, neuron death. Noopept modulates neuroreceptor function keeping glutamate transmission at normal levels. Protecting neurons and other brain cells from glutamate damage.
Noopept has also been shown to modulate acetylcholine flow in your brain. Restoring the harmony of glutamate and acetylcholine function not only protects your brain from damage. It can boost cognition, memory, learning, recall, mood and relieve anxiety.
2. Noopept increases Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and mRNA.
NGF is a unique protein crucial to the growth, maintenance, and survival of nerve cells, including brain cells. NGF is a key component in neurogenesis, or the body's ability to create new nerve cells. Brain-Derived Neurotrophic Factor (BDNF) has a similar role to NGF but is primarily active in the hippocampus, cortex, and basal forebrain, areas of the brain that are vital to learning, memory, and higher thinking. BDNF is one of the most important molecules involved in memory, playing a vital role in short-term and long-term memory formation. NGF and BDNF are directly related to neuroplasticity. This ability to repair and even grow new brain cells can have profound implications. Particularly with someone with neurodegenerative brain damage like Parkinson's or Alzheimer's. And even affecting Long-Term Potentiation(LTP) needed for long-term memory development. mRNA affects the expression of genes and intracellular communication in brain cells. This ongoing brain signaling and gene expression within brain cells is required for healthy cognition.
One study conducted in Moscow showed long-term use of Noopept boosted NGF, BDNF and mRNA. The animal subjects in this study showed no sign of tolerance. And long-term use of noopept even potentiated the neurotrophic effect.
Benefits & Effects
1. Boosting memory and cognition
Noopept can help increase cognitive capacity and recall ability. It also reduces the risk of cognitive decline. Recent studies show that with just one dose of this drug, people may experience an increase in the ability to learn new things.
In several animal studies done on rats, a single dose of noopept and chronic dosing of a similar amount over 28 days led to a notable increase of their nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Increased NGF and BDNF lead to cognitive enhancement and improved memory function. It also leads to long-term memory enhancement in rats. In another study conducted on people with cerebrovascular deficiencies, 20 mg of noopept was more effective than 1200 mg of piracetam at improving their global Mini-Mental State Exam (MMSE) scores showing a cognitive enhancement from use. These results were clearer in persons with post-traumatic cerebral insufficiency and impaired brain function. N-phenylacetyl-L-prolylglycine ethyl ester is effective at improving cognitive processes.
2. Increasing NGF & BDNF
A study published by the Russian Academy of Medical Sciences in Moscow shows that Noopept stimulates Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
In this study, researchers studied the effect of single and long-term treatment (28 days) of noopept. They found that one-time treatment boosted mRNA in the cerebral cortex of rats. mRNA is a molecule in brain cells that carries codes from DNA where they specify the amino acid sequence of proteins.
Neurogenesis is known to improve the performance of neural networks within the brain, and better brain structure is associated with enhanced performance in virtually all areas of cognition. Low levels of NGF are associated with various disorders, including dementia, Rett syndrome, schizophrenia, Alzheimer's, bipolar disorder, and acute coronary and metabolic syndromes. And long-term treatment of noopept increased Brain-Derived Neurotrophic Factor (BDNF). The researchers speculated that this sequence of events in the brain plays a role in the restoration of neurons. Improving neurotrophin synthesis in the hippocampus boosts cognitive function, particularly consolidation and delayed memory retrieval.
3. Improving emotional balance
A common claim made about noopept is its ability to improve mood, reduce anxiety, lower stress, and combat depression. No hard evidence exists to support these claims. However, preliminary studies have also shown early promise in this case.
A clinical study on noopept benefits on patients with cognitive disorders resulting from traumatic brain injury or stroke showed that it improved their emotional states. Almost half of subjects who used a 10 mg dose reported a reduction in fatigue, brain fog, irritability, and anxiety. Noopept also improved their mental stability within a week of using it. They also reported other benefits, including sleep improvement and reduced occurrence of headaches. Besides that, they reported improved moods and better wakefulness as well. These results show noopept's ability to regulate moods and emotions.
4. Boosting brain waves
Researchers in Moscow studied the effects of noopept in rats to see how it would affect brain waves. The team found that noopept increased Alpha and Beta brain wave activity throughout the brain.
People experience Alpha waves as they become more relaxed. Alpha waves are associated with super-learning, flow state and joy. Beta waves are associated with concentration, alertness and cognition. The researchers observed that NMDA receptors were involved with a single injection of noopept. While AMPA receptors were activated after longer-term use of noopept. NMDA receptors are associated with Long-Term Potentiation (long-term memory) and neuroplasticity. AMPA receptors are associated with increased brain signaling activity.
5. Neuroprotective Properties
Various studies demonstrate that noopept has powerful neuroprotective properties that help protect the brain from various factors that impair cognition.
Noopept is a potent antioxidant that protects cells against oxidative damage from free radicals, incomplete molecules formed when the body is exposed to contaminants or stressors. Oxidative damage is closely associated with age-related cognitive decline and neurodegenerative disorders such as Alzheimer's disease. It is also an effective anti-inflammatory agent, which may further protect and enhance cognition; systemic inflammation is associated with loss of spatial reasoning, short-term memory, verbal proficiency, verbal learning and memory, and executive function. What's more, noopept also protects and promotes neurological health by improving blood flow to the brain and inhibiting neurotoxicity caused by excess calcium and glutamate.
Is it safe to take?
Generally, noopept is safe to take. However, studies on its side effects and long-term health risks remain elusive. We cannot state with any certainty if this nootropic is safe to use for extended periods. No evidence exists to show any long-lasting damage from using noopept. Before taking noopept or any other nootropic supplement, please make sure you read its instructions and medical disclaimer before use. You may need a full assessment before any noopept administration, especially if you have a history of memory loss, headaches, cognitive disturbances, or seizures. Noopept may also have adverse drug interactions with other medicines, although so far, there are no recorded cases.
In a word, we strongly advise you to seek the advice of a professional doctor before taking noopept or any other nootropic drug.
Factory & Certificates
Shipping & Packaging
FAQ
1. How to contact Xi'an Sonwu supplier and inquire products?
You can contact Xi'an Sonwu by the email, telephone number and social media.
2. How to ensure the product's quality before order?
Each batch of products need to be tested, so Xi'an Sonwu can supply COA for customers. Additionally, all products have passed the test: HPLC, UV, GC, TLC etc., and Xi'an Sonwu also cooperate with the third parties, like SGS.
3. How to pack and store noopept?
Pack: Sealed export grade drum and vacuum sealed foil packaging, or Xi'an Sonwu can pack the goods according to customers' need.
Storage: Please store them in cool & dry place. Keep away from strong light and heat.
If you want to buy noopept powder, welcome to contact Xi'an Sonwu.
Email ID: sales@sonwu.com
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