Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of mkc-231 powder in China. We warmly welcome yuo to wholesale bulk mkc-231 powder for sale here from our factory. Quality products and reasonable price are available.
Coluracetam Supplement
MKC-231 powder, also known as BCI-540 or coluracetam powder, is a synthetic nootropic compound belonging to the racetam class of derivatives. Originally developed by Mitsubishi Tanabe Pharmaceutical Co., Ltd. in Japan, it was initially used to study central nervous system-related diseases such as Alzheimer's disease and major depressive disorder. Its method of action, which is different from that of conventional racetams, is its most important feature. By increasing high-affinity choline uptake (HACU), it mainly stimulates acetylcholine production and improves cholinergic neurotransmission function.
MKC-231 may improve memory formation, learning, and cognitive flexibility, according to studies, especially in models with compromised cholinergic function. Additionally, it may have an impact on anxiety reduction, mood control, and sensory acuity (including color perception and visual clarity), according to some research. However, the majority of these conclusions are still derived from animal testing or small-scale studies.
As a novel cognitive-enhancing drug with a relatively unusual mechanism, it has some academic value in the field of cholinergic system and cognitive function research. However, additional comprehensive clinical research is still needed to verify its efficacy and safety. If you need Coluracetam, Xi'an Sonwu can supply it. Xi'an Sonwu is looking forward to hearing from you.
Certificate Of Analysis
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Assay |
≥99.0% |
99.15% |
|
Appearance |
White Powder |
Complies |
|
Solubility |
Freely soluble in water, soluble in ethanol |
Complies |
|
Loss on drying |
≤1.0% |
Complies |
|
Heavy metals |
≤10ppm |
Complies |
|
Isopropanol |
NMT2000ppm |
Complies |
|
Methanol |
NMT1500ppm |
Complies |
|
Salmonella |
Negative |
Negative |
|
Particle size |
100%through 80 mesh |
Complies |
|
Residue |
<0.3% |
Complies |
|
Conclusion |
The product conforms to in House Standard. |
|
Coluracetam Buy Online
Xi'an Sonwu Biotech Co., Ltd. has extensive experience in global trade and the healthcare industry. Insisting on faith-based, quality-first principles is our guiding principle. We strictly control product quality, which means selection begins with the raw materials. Additionally, we handle every detail and minimize costs to the maximum, allowing our customers to obtain cost-effective products. Based on this, customers have given a lot of good feedback about our products. When purchasing MKC-231, look for Xi'an Sonwu Biotech Co., Ltd.
Xi'an Sonwu ensures product quality and can provide samples upon request. Here is the quantity.
|
MKC-231 Form |
Sample Amount |
MOQ |
|
Powder |
5g |
5g |
|
Bulk Capsules |
1000 capsules |
1000 capsules |
|
Bottle Capsules |
10 bottles |
10 bottles |
Customers' Good Comment
OEM Service
Xi'an Sonwu can supply high-quality MKC-231 powder and its capsules.
So customers can customize the capsules they want. The items below can be supplied.
Customized capsule shells (size, color, material)
Customized bottles(size, color, material, style)
Customized packaging(vacuum foil packaging, box, drum)
Customized label(paint film, matte film, optical mask)
What Is Coluracetam Used For
The main usage of coluracetam is in research, especially in the fields of cognitive science and neuroscience.
Main uses of MKC-231
1. Cognitive and memory research
BCI-540's possible effects on memory formation, learning, and cognitive function are being investigated. Unlike traditional racetams, it works by increasing high-affinity choline uptake (HACU), which encourages acetylcholine synthesis in neurons.
2. Neurodegenerative disease research
For diseases like Alzheimer's disease and age-related cognitive decline, it has been studied in preclinical and restricted clinical settings, particularly when cholinergic function is compromised.
3. Depression and mood disorder research
MKC-231 was investigated in early clinical studies as a possible treatment for treatment-resistant depression, especially in individuals with co-occurring anxiety. Due to their limitations, these investigations did not result in regulatory approval.
4. Neuroprotection studies
Coluracetam's possible neuroprotective qualities, such as its capacity to repair cholinergic signaling following neuronal damage, are being investigated by researchers.
5. Pharmacology and mechanism-of-action studies
Research on cholinergic neurotransmission, synaptic plasticity, and cognition-related pathways frequently uses it as a reference molecule.
Is Coluracetam Water Soluble
Water does not dissolve coluracetam.
Solubility profile
Water: Almost insoluble or very poorly soluble
Organic solvents: Soluble in polar organic solvents like ethanol and DMSO
Nature: Lipophilic, fat-soluble material
BCI-540's solubility in water is limited by its somewhat lipophilic molecular structure and lack of strongly ionizable groups. As a result, under typical circumstances, it does not form a proper aqueous solution.
Practical implications
MKC-231 is usually dissolved in ethanol or DMSO for laboratory research and then diluted if necessary.
Without the addition of solubilizers or sophisticated formulation processes, it is not appropriate for basic water-based formulations.
One reason it can pass across the blood–brain barrier more easily in research settings than water-soluble substances is because of its lipophilicit.
Coluracetam Dosage
Coluracetam dosage needs to be handled carefully because it is not an FDA-approved drug and has no officially established therapeutic dose. The information below is for research and informational purposes only, not medical advice.
Dosage ranges reported (research/non-clinical setting)
Drawing on extensively regarded non-clinical findings and early clinical research:
Context of human research
20–80 mg daily is the typical researched range.
frequently split into two doses (morning and afternoon, for example).
Doses in this range were investigated in early depression clinical studies.
Use for research and experiments (not authorized)
Low dosage: 10–20 mg daily
30–50 mg daily is a moderate dose.
Higher range (less frequent): up to about 80 mg daily
Clinical data does not support doses over this range, which raises safety concerns.
Duration
MKC-231 is typically mentioned for short-term (days to weeks) use rather than long-term continuous dosage in studies and research talks.
Important safety notes
Not approved as a medication or dietary supplement
No standardized dosing guideline
Long-term safety data is limited
Possible side effects reported in research/anecdotal contexts include:
Headache
Fatigue
Nausea
Mood changes
Regulatory status
Research chemical only
Typically labeled "For research use only."
Legal and regulatory status varies by country
Coluracetam Half Life
Due to the lack of publicly available comprehensive human pharmacokinetic data, coluracetam's half-life is not well documented.
What is understood
No human half-life has been formally published.
Although coluracetam was investigated in early clinical studies, peer-reviewed literature did not provide specific PK parameters, such as half-life.
Based on scant study findings, it is regarded as a short- to moderate-acting molecule.
Commonly cited estimates (non-official)
From discussions of experiments and secondary research reports:
Half-life estimate: roughly three to five hours
This estimate should only be used for informative purposes as it has not been clinically validated.
Practical interpretation (research context)
It's common to say that effects last for several hours.
Research procedures frequently refer to divided daily exposure rather than a single long-acting dose since this is consistent with the notion of a relatively short half-life.
Factory
1. Xi'an Sonwu has a factory with sufficient stock. Additionally, Xi'an Sonwu boasts a clean and well-organized production department equipped with advanced machinery. Under the company's leadership, researchers continue to develop new products to meet customers' needs.
2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.
Certificate
Packing
Logistics Update
In addition to guaranteeing product quality, the other most vital thing is that clients receive the goods smoothly. Therefore, Xi'an Sonwu offers a variety of couriers to meet different needs.
FAQ
1. How to inquire?
We can be reached by phone, email, or social media.
2. How do you guarantee the quality of products?
Each batch must be tested, and a COA can be supplied to customers. Additionally, all products pass the following tests: HPLC, UV, GC, and TLC, among others. We also cooperate with third parties, such as SGS.
3. How do you pack and store?
Packaging: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods as requested by the customer.
Storage: Store it in a dry, cool place, away from sunlight.
For information about the MKC-231 powder, please contact Xi'an Sonwu. Click the email, and then you will receive a high-quality Coluracetam powder.
Email: sales@sonwu.com
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