Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of coluracetam capsules in China. We warmly welcome yuo to wholesale bulk coluracetam capsules for sale here from our factory. Quality products and reasonable price are available.
What's the Coluracetam
Coluracetam capsules are produced by Coluracetam, which is a new and unique member of the racetam class of synthetic nootropics. So what's the racetam?
Racetams are a popular class of nootropics used to enhance cognitive functions and counter cognitive decline in seniors. Piracetam and Aniracetam are among the most popular racetam drugs. One of the lesser-known racetams is Coluractem, which has been around since the 1990s. It is not as well-studied as some of the other nootropics, but it is still linked to several brilliant cognitive-enhancing properties that may benefit both healthy adults and old people. Coluracetam, also known as BCI-540 or MKC-231, was originally developed as a potential treatment for Alzheimer's disease, and later as a treatment for depression and anxiety. Currently, coluracetam has become a popular nootropic known for improving mood, increasing motivation and enhancing vision.
Parameters
ANALYSIS | SPECIFICATION | RUSULT |
Assay | ＞99.0% | 99.23% |
Appearance | White Crystalline Powder | Conforms |
Flash Point | 337.3±31.5℃ | Conforms |
Boiling Point | 634.1±55.0℃ at 760mmHg | Conforms |
Loss on Drying | ≤0.5% | 0.14% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metals | ≤20ppm | Conforms |
Chromatographic Purity (HPLC) | Max single impurity: ≤0.5% | 0.02% |
Total impurities: ≤1.0% | 0.08% | |
Conclusion | Conforming to Enterprise Standard | |
Benefits & Effects
At present, there have been few documented human studies on Coluracetam, so most of the information available now is based on animal testing. However, research results and self-reports from users all suggest that Coluracetam may provide various cognitive and physical/sensory benefits.
1. Improving memory and learning
In the study, scientists used rats as experimental subjects to study the function of Coluracetam. They investigated the effects of Coluracetam on rats treated with a cholinergic neurotoxin AF64A. Basically, these rats had a nerve toxin that had seriously affected the choline uptake system. They gave the rats 1 and 3 mg/kg for several days. At the end of the study, the researchers found the significant improvement in both learning and memory, which had been affected by the damaged choline uptake system. Interestingly, the effects were observed even after the treatment ended. The results also suggest that the product may benefit Alzheimer's patients who are known to have low levels of acetylcholine. And Coluracteam can address this by increasing choline uptake and the enzyme ChAT. The product can also protect individuals at risk of developing Alzheimer's.
What's more, according to the report, some users said that Coluracetam can dramatically improve the ability of short-term memorizing and free recall, increase the ability of memorization and enhance reading comprehension ability and increase the speed of thought and learning.
2. Fighting depression and anxiety
Another study also showed that Coluracetam could treat depression and anxiety in individuals who are resistant to other treatments. This study involved patients with generalized anxiety disorder and major depressive disorder. They were given 240mg per day, which was split into three servings. By the end of the testing period, their symptoms had all improved.
3. Boosting eyesight
Coluracetam capsules are made from Coluracetam, which is an interesting nootropic compound that not only enhances cognitive function but can also boosts human's vision through improving color vision, better shaping recognition and improving eyesight. It can encourage the growth of nerves in people affected by the degenerative disease of the retina. According to the report about the users' experience of taking Coluracetam, they state that the effects could include brighter colors, intense contrast, sharp focus on shapes and lights becoming more radiant.
How does it work
Just like other racetams, Coluracetam benefits the brain by affecting the choline and subsequently the acetylcholine in different ways. The research conducted suggests that the Coluracetam works in the brain mainly through three mechanisms. The details are elaborated below:
1. Supporting high-affinity choline uptake
Nootropics in the racetam class are known to induce the production of acetylcholine by stimulating the responsible receptors. Acetylcholine is a key neurotransmitter involved in learning, memory, and other brain functions. The coluracetam mechanism of action is unique in that it enhances production of acetylcholine by enhancing the high affinity choline uptake (HACU). The HACU system is the central mode by which choline is transported to the brain. It is basically the rate-limiting step in the process of acetylcholine production. Coluracetam supplements increases the rate at which choline is transported into the brain resulting to more production of acetylcholine. It specifically increases the CHT1, a high-affinity choline transporter, hence lead to high availability of choline for uptake.
The increased acetylcholine production in the neurons helps boost short and long-term memory, learning, as well as better decision-making ability.
2. Improving AMPA potentiation
Coluracetam capsules, according to the research, can enhance alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) potentiation. AMPA receptors are influenced by glutamate which in turn affects the long-term potentiation (LTP) which forms the basis for learning and memory.
Currently, Serotonin Selective Reuptake Inhibitors (SSRIs) are the drugs used in treatment of mood disorders and depression in the market. These SSRIs, however, could affect the serotonin levels in the brain which cause many adverse side effects.
Coluracetam comes in handy as treatment for depressive disorders and anxiety by enhancing glutamate activity hence does not cause any serotonin-related adverse reactions.
3. Protecting the NMDA receptors from the harmfulness of glutamate toxicity
Another possible mechanism of coluracetam's action is the ability to protect the N-Methyl-D-aspartate (NMDA) receptors from glutamate toxicity. The NMDA receptor is a glutamate receptor and also an ion channel protein occurring in the nerve cells. It plays a vital role in the control of synaptic plasticity and memory activities.
Damage to the NMDA receptors is linked to key brain disorders such as stroke, traumatic brain injury, Alzheimer's disease and so on.
References:
https://www.phcoker.com/coluracetam/
https://rhtp.org/coluracetam/
Coluracetam Application
The benefits of coluracetam nootropics are promising. It is believed to offer profound benefits in enhancing memory, learning, relieving anxiety, major depressive disorder as well as improving vision. Many users count on it as a reliable mood lifter and memory enhancer that gives them better focus and concentration.
Coluracetam capsule and powder are two kinds of popular forms in the market.
Factory Environment
Xi'an Sonwu Biotech Co., Ltd. is a professional manufacturer with its own factory, so there's plenty of stock. The clean and tidy production workshop with advanced equipment provides customers with high quality products.
Xi'an Sonwu supplier has professional researchers who constantly develop new products to meet the needs customers' need as well.
The company also has professional and advanced testing equipment and testers to ensure the quality and accuracy of the products, which also proves its professional and rigorous working attitude and confidence in being able to provide quality services for customers.
Shipping & Packaging
Certification
Company's Introduction
Xi'an Sonwu Biotech Co., Ltd. is a professional manufacturer and supplier in China. It was founded in 2012 and sited in a high-tech industrial development zone of Xi'an, the capital of Shaanxi Province.
It specializes in the development, research and production of food additives, APT, plant extract and other raw ingredients of health care products. At present, it supplies five kinds of raw material products: Nootropics, API, Anti-hair Loss Powder, Muscle Building Products, and Plant Extract.
Xi'an Sonwu firmly believes that the foundation of an outstanding company lies in its high-quality products and excellent service. Xi'an Sonwu Biotech Co., Ltd has been doing this all the time. So, welcome your inquiry.
If you're interested in Coluracetam, welcome to contact with Xi'an Sonwu Biotech Co., Ltd.
Email: sales@sonwu.com
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