7,8-DHF

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 7,8-dhf in China. We warmly welcome yuo to wholesale bulk 7,8-dhf for sale here from our factory. Quality products and reasonable price are available.

7,8-Dihydroxyflavone

7,8-DHF (7,8-Dihydroxyflavone) is a naturally occurring flavonoid with various biological and pharmacological activities found in Godmania aesculifolia, Tridax procumbens, and primrose leaves. It has been found to act as a potent and selective small molecule agonist of tropomyosin receptor kinase B, the primary signaling receptor for the neurotrophin brain-derived neurotrophic factor.

Recent studies have shown that it can enhance the growth and survival of nerve cells, promote neuron differentiation and synapse formation, and has potential therapeutic effects on the protection and repair of the nervous system. Studies have shown that it can pass through the blood-brain barrier, effectively mimic brain-derived neurotrophic factors, and specifically bind to TrkB receptors, thereby inducing TrkB dimerization and autophosphorylation and further activating the three downstream signaling pathways of MAPK/ERK, PI3K/ Akt and PCγ1. It is currently applied to the prevention and treatment of various BDNF/TrkB signaling-related diseases and has achieved exciting results. It is a high-purity natural compound with broad application prospects in medical and biological research. It can be used for neuroprotection, neuro repair, and other neurological-related diseases, such as Alzheimer's disease, Parkinson's disease, brain injury, neurodegenerative diseases, etc. In addition, it can also be used for anti-oxidation, anti-inflammation, and immune regulation. 7,8-Dihydroxyflavone is widely used in daily life. If you are interested in raw 7,8-dihydroxyflavone, please get in touch with Xi'an Sonwu online.

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Where To Buy 7,8-Dihydroxyflavone

Xi'an Sonwu Biotech Co. Ltd. is a manufacturer and distributor with more than ten years of experience. It has extensive and stable cooperation with countries worldwide in the Americas, Asia, Europe, and Oceania. Xi'an Sonwu has always insisted on product quality first; serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from the selection of raw materials, and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need dihydroxyflavone powder, please get in touch with Xi'an Sonwu.

Xi'an Sonwu entirely makes sure of the product quality and supplies the samples. Please check the quantity.

Customers' Good Comment

OEM Service

Xi'an Sonwu not only can supply high-quality dihydroxyflavone supplement powder and capsules.

So any customers could customize the capsules they want. And items below can be supplied.

1. Customized capsules shells (size, color, material)

2. Customized bottles(size, color, material, style)

3. Customized packaging(vacuum foil packaging, box, drum)

4. Customized label(paint film, matte film, optical mask)

What Are The Benefits Of 7,8-Dihydroxyflavone Powder

7,8-DHF is a natural compound that belongs to flavonoids and widely exists in plants and foods. In recent years, studies have found that it has various biological effects, including neuroprotection, anti-oxidation, and anti-inflammation. In addition, it has also been found to act on multiple signaling pathways and targets, including TrkB, AMPK, PI3K/Akt, CREB, etc.

1. Neuroprotective effect

7,8-Dihydroxyflavone can specifically activate TrkB receptors, thereby promoting the growth and survival of nerve cells, and has a protective effect on the nervous system. It can reduce neuronal injury caused by hypoxia-ischemia, nerve cell mortality caused by hypoxia-ischemia, and brain injury. In addition, it can also promote neuronal synapse formation and plasticity, increase synaptic connections of neurons, and high neurotransmission function. Therefore, it is considered a potential neuroprotective agent for treating neurological diseases such as stroke, Alzheimer's disease, Parkinson's disease, etc.

2. Antioxidant effect

Oxidative stress is an essential link in the occurrence and development of many diseases. It has been found to have antioxidant effects that can reduce cellular damage and inflammation caused by oxidative stress. Studies have shown that it can reduce free radical production, increase antioxidant enzyme activity, and reduce Oxidative stress-induced DNA damage and apoptosis. In addition, it can also reduce the release of inflammatory mediators and the expression of cytokines and inhibit inflammatory and immune responses. Therefore, it is considered a natural compound with antioxidant and anti-inflammatory effects, which can treat various diseases, such as cardiovascular diseases, diabetes, etc.

Target

1. AMPK pathway

AMPK is a vital energy receptor that regulates cell energy metabolism and biosynthesis. Studies have shown that 7,8-Dihydroxyflavone can activate the AMPK pathway, promote glucose uptake and oxidative metabolism, and reduce fatty acid synthesis and lipid accumulation. In addition, it can promote mitochondrial biogenesis and autophagy, increasing cells' energy supply and metabolic activity.

2. PI3K/Akt pathway

PI3K/Akt pathway is one of the critical pathways of cell signal transduction, which can regulate cell proliferation, apoptosis, and metabolism. Studies have shown that 7,8-Dihydroxyflavone can inhibit the activity of the PI3K/Akt pathway and reduce the proliferation and metastasis of tumor cells. In addition, it can promote apoptosis and cell cycle arrest and inhibit the growth and spread of tumor cells.

3. CREB pathway

CREB is a transcription factor in cells that can regulate the expression of various genes and cell proliferation, differentiation, and survival. Studies have shown that 7,8-Dihydroxyflavone can activate the CREB pathway, promote neuron growth and synapse formation, and enhance the function and adaptability of the nervous system. In addition, it can also improve memory and learning ability and plays a vital role in preventing and treating cognitive impairment.

4. TrkB pathway

TrkB plays a critical role in the development and regeneration of the nervous system and is a neurotrophic factor receptor. 7,8-Dihydroxyflavone is a TrkB receptor agonist that promotes neuronal growth and survival. It can bind to TrkB receptors, promote neuronal development and protect neurons from damage such as oxidative stress and inflammation.

5. MAO-B pathway

MAO-B is a neurotransmitter metabolizing enzyme that degrades dopamine and other neurotransmitters. 7,8-Dihydroxyflavone also inhibits monoamine oxidase B (MAO-B), which increases dopamine levels. It inhibits MAO-B, which increases dopamine levels and thus has antidepressant and anxiolytic effects.

Factory

1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.

2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

Certificate

Packing

Logistics

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ

There are not sufficient studies to show the accurate side effects. But, the users still need to be careful some symptoms that may occur:

1. Overstimulation

2. Restlessness

3. Dizziness

4. Nausea

5. Irritability

If you want to know a dihydroxyflavone manufacturer, you can contact Xi'an Sonwu. Click the email then you get high-quality 7,8-DHF powder.

Email: sales@sonwu.com

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