What Is The Formula For N 4 Hydroxyphenyl Acetamide
4 Maleimidophenol powder's chemical name is N 4 hydroxyphenyl acetamide. Its structure consists of a maleimide group and a benzene ring with an attached hydroxyl (OH) group at the para position (4). The maleimide group is an essential chemical functional group with two carbonyl groups (C=O) and a double bond forming a five-membered ring structure. That is an organic compound with a maleimide group attached to the hydroxyl group on the benzene ring. This compound may play a role in material science or drug synthesis. The maleimide group is highly chemically reactive, especially with sulfhydryl (-SH) groups. This property makes 4-Maleimidophenol widely used in biochemistry and material science. The maleimide group can react with sulfhydryl-containing compounds (such as cysteine residues in proteins) to form a stable thioether bond. This reaction works best under neutral to slightly alkaline conditions, usually between pH 6.5 and 7.5. This reactive property makes 4-Maleimidophenol an essential reagent for protein labeling and modification. It assists researchers in learning more about the relationships and functions of proteins by serving as a tool for protein labeling and modification. As a cross-linker for polymers and materials, it improves materials' mechanical properties and chemical resistance. So, if you are interested in intermediates, you can contact Xi'an Sonwu, who can provide you with raw powder.
N 4 Hydroxyphenyl Acetamide Uses
1. Biochemical Applications
Protein Labeling and Modification
4-Maleimidophenol can label and modify proteins by reacting with cysteine residues in proteins. It can attach fluorescent dyes, drug molecules, or other functional molecules to proteins, facilitating the study of protein function, localization, and interaction. 4-Maleimidophenol can be employed in biosensors to immobilize enzymes or antibodies to the sensor surface, increasing the sensor's sensitivity and specificity.
Biomolecule Cross-linking
4-Maleimidophenol can be used as a cross-linker to link two or more proteins to form a multifunctional complex. This cross-linking cross-linking is very useful in studying the structure and function of protein complexes. It can synthesize antibody-drug conjugates (ADCs) by linking drug molecules to antibodies to specifically target cancer cells or other diseased cells and reduce toxicity to healthy cells.
Nucleic Acid Modification
4-Using fluorescent probes or other detecting molecules to bind nucleic acid molecules for fluorescence in situ hybridization (FISH) and other molecular biology procedures is one way that it can label and alter oligonucleotides.
2. Applications in Materials Science
Polymer Synthesis
In polymer chemistry, 4-Maleimidophenol is used as a cross-linker to form a highly cross-linked network structure by reacting with thiol groups in polymer chains. That can significantly improve polymers' mechanical strength, thermal stability, and chemical resistance. By introducing 4-Maleimidophenol on the polymer backbone, functionalized polymers can be prepared to develop intelligent and responsive materials.
Coatings and Adhesives
Adding 4-Maleimidophenol to coatings and adhesives can improve their adhesion and durability. Its reactive groups can chemically react with the coating's constituents or the substrate's surface to strengthen and stabilize the coating's connection. When used in anti-corrosive coatings, the cross-linking properties of 4-Maleimidophenol can form a dense protective layer, effectively isolating corrosive media and extending the material's service life.
Nanomaterials
4-Maleimidophenol can be used for surface functionalization of nanoparticles to give them specific biocompatibility and targeting. For example, in drug delivery systems, functionalized nanoparticles can more effectively target diseased tissues or cells and increase therapeutic effects.
3. Other applications
Photosensitive materials
In microelectronics and optoelectronics, it can be used to prepare photoresists. The irradiation of ultraviolet rays or other light sources undergoes cross-linking reactions to form delicate patterns for use in semiconductor manufacturing and micromachining technology.
Catalyst support materials
4-Maleimidophenol can be used to immobilize catalysts. The catalyst molecules are fixed on the support material through chemical reactions to improve the stability and reusability of the catalyst.
N 4 Hydroxyphenyl Acetamide Toxicity
4-Maleimidophenol is an organic compound with many applications in biochemistry and materials science. However, as with all chemicals, its potential toxicity and side effects must be noted when used.
Toxicity
Acute toxicity
Inhalation: Inhalation of 4-Maleimidophenol dust or vapor may cause respiratory irritation, with symptoms including coughing, sore throat, and difficulty breathing.
Skin contact: Skin irritation can result from direct contact with the skin and manifests as burning, itching, and redness.
Eye contact: Severe eye irritation can result from contact with the eyes; symptoms include redness, tears, and blurred vision.
Ingestion: When consumed, it may produce upset stomach, nausea, and vomiting, among other digestive problems.
Chronic toxicity
Long-term exposure to 4-Maleimidophenol may cause skin allergic reactions, manifesting as contact dermatitis. Repeated or long-term exposure may lead to more severe health problems.
Side effects
Skin allergies
4-Maleimidophenol may cause skin allergic reactions, especially in sensitive people. Prolonged or repeated contact may cause allergic symptoms such as skin redness, itching, and rash.
Eye irritation
Eye irritation like redness, tearing, and pain. In severe cases, vision may be affected.
Respiratory tract irritation
Inhalation of dust or vapor may cause upper respiratory tract irritation with symptoms including coughing, sore throat, and difficulty breathing. Long-term exposure may cause chronic respiratory problems.
If you want a 4 Maleimidophenol price, are interested in Xi'an Sonwu, or have other questions about the product, do not hesitate to contact Xi'an Sonwu.
Email: sales@sonwu.com