What Is 4-Maleimidophenol
4 maleimidophenol powder, as a specific chemical entity, represents a class of compounds in which the maleimide group is covalently bonded to the phenol structure at the 4-position. It has properties of maleimide and phenol. Its thermal stability is noteworthy, allowing it to withstand conditions that promote various chemical reactions without significant decomposition. The molecule is adaptable to multiple chemical and material conditions because of its solubility in organic solvents and its capacity to create hydrogen bonds because of the phenolic hydroxyl groups. Maleimide groups are known for their high reactivity toward nucleophiles, especially thiols, under mild conditions, making them highly valuable for bioconjugation and materials science applications. The phenol group increases its reactivity, allowing further functionalization and modification.
This particular structure provides a unique combination of reactive functional groups (maleimide and phenol groups), making it an attractive compound for various chemical synthesis and materials science applications. In organic synthesis, 4-maleimide phenol can be a building block for complex molecules. Its dual reaction sites allow for sequential or orthogonal reactions, facilitating the synthesis of various pharmaceuticals, agrochemicals, and material compounds. In materials science, 4-maleimidephenol is used as a cross-linker to prepare high-performance polymers. Maleimide groups react with free thiol groups in the polymer to form cross-linked structures that exhibit enhanced thermal, mechanical, and chemical resistance. If you are interested in products with such properties, please feel free to contact Xi'an Sonwu. Xi'an Sonwu can provide you with 99 powder 4 maleimidophenol
Certificate Of Analysis
ANALYSIS |
SPECIFICATION |
RESULT |
Appearance |
Yellow crystal powder |
Conform |
Loss on Drying |
≤0.50% |
0.36% |
Residue on Ignition |
≤ 0. 10% |
0.07% |
Heavy Metals |
≤10ppm |
<10ppm |
Max Single Impurity |
≤0. 10% |
Conform |
Total Impurities |
≤0. 10% |
0. 04% |
Density |
1.47 g/cm3 |
Conform |
Boiling Point |
397ºC at 760 mmHg |
Conform |
Solubility |
It has good solubility in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but poor solubility in water. Specific solubility will be affected by conditions such as temperature. |
Conform |
Assay |
98.0% |
98.37% |
Where To Buy 4 Maleimidophenol
Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. Xi'an Sonwu has established solid and reliable partnerships with countries in America, Asia, Europe, and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to meet their needs fully.
Every stage of the Xi'an Sonwu production process, beginning with the meticulous selection of raw materials, is tightly regulated. High-quality products are Xi'an Sonwu's top priority, and the company's dedication to perfection is seen in all aspects of its operations, including the selection of raw materials, manufacturing processes, sample testing, and staff professionalism. Xi'an Sonwu may reduce expenses without sacrificing quality by carefully monitoring every detail, guaranteeing that clients receive items of remarkable value.
Xi'an Sonwu is proud of the positive feedback it has received from customers, who have consistently recognized the quality of the products. To further prove product confidence, Xi'an Sonwu will provide samples for you to test.
Form |
Sample Amount |
The Minimum Of Quantity |
Powder |
50g |
50g |
Customers' Good Comment
4 Maleimidophenol Effect
1. In the field of materials science
Cross-linking agent
4 maleimidophenol powder can be used as an effective cross-linking agent. The maleimide group is reactive towards thiols. High-performance electronics, automotive, and aerospace applications can benefit significantly from this cross-linking, which can substantially increase the polymer's mechanical strength, thermal stability, and chemical resistance.
Surface modification
It can be used to modify surfaces and materials to introduce specific functionality. For example, coating surfaces with 4-maleimide phenol can bond more easily to other materials or impart particular chemical properties to the surface.
2. In bioconjugation
Targeted drug delivery
The maleimide group in 4-maleimide phenol can selectively react with thiol groups present in proteins or peptides, thereby achieving targeted binding of drugs to biomolecules. This specificity can be used in targeted drug delivery systems to reduce side effects and improve therapeutic efficacy.
Diagnostic applications
Similar selective conjugation properties make 4-maleimide phenol valuable in designing diagnostic tools, such as attaching fluorescent markers to antibodies for imaging and detection purposes in research and medical diagnostics.
3. In the fields of organic synthesis and pharmaceuticals
Synthesis of complex molecules
The dual reaction sites of 4-maleimide phenol make it a versatile building block in organic synthesis, helping to create complex molecules with potential applications such as pharmaceuticals, agrochemicals, or novel organic materials.
Drug intermediates
Its role as an intermediate in the synthesis of pharmaceutical compounds is crucial. It can be used to introduce maleimide moieties into drug molecules, potentially altering their pharmacokinetic properties or enabling the drug to target specific cells or receptors in the body more effectively.
4 Maleimidophenol Side Effect
Impact on the environment
The environmental impacts of 4-maleimide phenol, although not widely documented in public resources, are a concern similar to other synthetic chemicals. Their release into the environment should be minimized to prevent harm to aquatic life and broader ecosystems. Proper disposal procedures and containment measures are essential to mitigate adverse environmental impacts.
Unexpected reaction in application
Unexpected reactions can be considered "side effects" of using 4-maleimide phenol in chemical synthesis or materials science applications:
Reactivity: The maleimide group is highly reactive toward thiols, but under certain conditions, it may undergo unwanted side reactions such as hydrolysis, which may affect the purity or functionality of the final product.
Compatibility: In complex formulations or material composites, 4-maleimide phenol may interact with other ingredients in unforeseen ways that may affect the stability, color, or mechanical properties of the material.
How Does 4 Maleimidophenol Work
The functionality and applications of 4-maleimide phenol are deeply rooted in its chemical structure, which combines a maleimide group with a phenolic moiety. The way it works or its mechanism of action varies in different fields, such as materials science, chemical synthesis, and bioconjugation, depending on the inherent properties of the maleimide and phenolic groups.
The maleimide group is highly reactive toward thiols (-SH group) under mild conditions. When 4-maleimide phenol is incorporated into polymers or materials containing thiol groups, it can form stable covalent bonds with these thiols, resulting in cross-linking. Cross-linking enhances the material's mechanical strength, thermal stability, and chemical resistance. 4-maleimide phenol can change the physical properties of the polymer by using this cross-linking technique, making it more suitable for specific applications where materials with outstanding attributes are required, such as electronics, automotive, and aerospace. The specificity of the maleimide group for thiols may also enable 4-maleimide phenol to selectively bind to thiol groups present in cysteine residues of proteins or peptides. The creation of targeted drug delivery systems or diagnostic tools is made possible by this selective conjugation, which attaches medications, fluorescent tags, or other compounds to particular proteins or antibodies. In addition to reacting with thiols, the phenolic hydroxyl group in 4-maleimidephenol can also undergo various chemical reactions, such as esterification, etherification, etc., providing additional pathways for chemical modification and synthesizing derivative compounds.
Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture, and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.
Certificate
Package
Logistics
Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
FAQ
1. How to inquire?
We can be reached by phone, email, or social media.
2. How do you guarantee the quality of products?
Each batch must be tested, and COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We cooperate with third parties as well, like SGS.
3. How do you pack and store?
Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.
Storage: You can keep it in a dry and cool place and make it avoid sunlight.
If you want to know the 99 powder 4 maleimidophenol manufacturer, you can contact Xi'an Sonwu. Click the email, and then you get high-quality 4 maleimidophenol powder.
Email: sales@sonwu.com
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