Coenzyme Urolithin A powder has been a popular supplementation ingredient in the market now. Actually, Urolithin is divided into two types: Urolithin A and Urolithin B. Today, let's get to know and understand Urolithin A first.
What's the Urolithin A?
People all need energy to live. Energy powers our body's vital functions, from metabolic reactions to moving our muscles. Unfortunately, as we age, our energy levels decline. This is where urolithin A comes in. Urolithin A is produced by the gut flora and is a natural metabolite of ellagitannins, a class of compounds found in pomegranates and some other fruits and nuts. According to research, it is a potent gut metabolite that restores mitochondria and reverses muscle aging. Because of its efunction, pure urolithin A powder becomes necessary gradually in human's daily life.
So, what's the ellagitannins on earth?
Ellagitannins (ETs) is the natural dietary polyphenols found in various fruits and nuts, including walnuts, raspberries, strawberries, pomegranates, and many tropical fruits. There is growing evidence of numerous health benefits of ETs-rich foods. However, ETs are extensively metabolized and the absorption of their hydrolysis product, EA, is also very limited due to its hydrophobic structure. Thus, the beneficial effects of ETs-containing foods are likely attributable to EA-derived metabolites, namely urolithins, that are generated by the gut microbiota. Urolithins have been studied for their anti-oxidant, anti-inflammatory, anti-estrogenic properties and their anti-cancer effects.
What does the urolithin A do?
1. Boosting cellular energy in the mitochondria & Enhancing the muscle health of the old
This is one of the biggest benefits of urolithin A. In modern life, decreased quality of life and independence due to muscle loss constitute a growing health care problem among aging populations.
According to a research paper in the journal Nature Medicine, urolithin A has been confirmed to improve mitochondrial and muscle function, which can improve muscle strength and endurance during aging. As everyone knows, famously known as the powerhouse of the cell, mitochondria are microscopic organelles that convert glucose and oxygen into adenosine triphosphate (ATP) for energy. As people get older, mitophagy decreases in cells in the body, and mitochondrial function declines in older muscles, which is thought to be one of the main causes of age-related muscle damage. Taking Urolithin A can improve mitochondrial function by stimulating a process called mitophagy, that is a process by which damaged mitochondria are removed from the cell, thus promoting the growth and maintenance of healthy mitochondria, so as to delay the aging process and achieve anti-aging effects.
2. Anti-cancer
Studies conducted for the anti-cancer properties of Urolithin and the researchers were able to find out that Urolithin A can help in avoiding cancer like kidney, colon, prostate, breast, bladder, and liver cancer by blocking the cell cycle and preventing the cell growth that presented a role in spreading cancer.
3. Improving cardiac functions
Urolithin A helps restore heart mitochondria and prevents cardiac inflammation in patients with cardiovascular disease by preventing the blockage of blood vessels.
4. Reducing cholesterol
According to the test in a rat with an aortic injury( when the aorta receives laceration due to some force exerted on the artery), it shows that notwithstanding the high cholesterol dosage to the animal, the Urolithin can cause a decrease in LDLs that is mounting cholesterol level due to certain genetic factors.
Is Urolithin A safe? Any side effects?
Notably, using Urolithin A as a dietary supplement has achieved GRAS status from the US FDA (2018), meaning it is ‘Generally Recognised as Safe’ for human consumption in the proscribed range of 250 mg to 1000mg per dose. And Urolithin A does not have any documented adverse side effects.
Xi'an Sonwu Biotech Co., Ltd. is a professional manufacturer and supplier with the factory, which ensures sufficient stock of Urolithin A with high quality.
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References:
https://us-reviews.com/diet/benefits-urolithin-a-maintaining-strength
https://www.nickengerer.org/longevity-and-wellness/urolithin-a-supplement-benefits-mitophagy-interview
https://longevity.technology/lifestyle/what-is-urolithin-a-and-how-you-can-benefit-from-it/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315438/