Coenzyme q10 powder is one of the participating substances in the electron transport chain and aerobic respiration in the mitochondria of eukaryotic cells. It is a yellow to orange-yellow crystalline powder, odorless and tasteless, and easily decomposed when exposed to light. Coenzyme Q10 is a fat-soluble nutrient, which can not only provide power to the heart, but also has excellent functions of anti-oxidation and scavenging oxygen free radicals, and can prevent lipid peroxidation on the blood vessel wall, thus effectively preventing atherosclerosis The occurrence and development of sclerosis, and coenzyme Q10 itself does not have any toxic side effects. Its specific functions can be reflected in helping the heart to protect the heart muscle effectively, improving the aging state of the skin, resisting fatigue, and preventing disease.
Because coenzyme Q10 is a fat-soluble nutrient, it must be taken together with fatty substances to facilitate daily absorption. Therefore, taking it with meals or within half an hour after meals is recommended. Coenzyme Q10 is generally taken orally three times a day. It would be best to take it at breakfast, lunch, or dinner or within half an hour after a meal for the best effect.
What Are The Pharmacological Properties Of Coenzyme Q10
Coenzyme Q10 has the function of promoting oxidative phosphorylation reaction and protecting the integrity of biofilm structure. This product is a fat-soluble quinone compound that widely exists in organisms. Coenzyme Q10 from different sources has different numbers of side-chain isoamyl units. Humans and mammals have ten isoamyl units, so it is called coenzyme Q10. Coenzyme Q10 plays an essential role in proton translocation and electron transfer in the respiratory chain in the body. It is an activator of cell respiration and metabolism and an important antioxidant and non-specific immune enhancer.
Animal experiments have confirmed that this product mainly has the following pharmacological effects:
(1) It can alleviate the weakening of myocardial contractility and the content of creatine phosphate and adenosine triphosphate during acute ischemia, maintain the morphology and structure of mitochondria in ischemic cardiomyocytes, and have a particularly protective effect on ischemic myocardium.
(2) Increase cardiac output and reduce peripheral resistance, which is beneficial to anti-heart failure treatment and may inhibit the synthesis and secretion of aldosterone and block its effect on renal tubules.
(3) When perfusing the isolated ventricular muscle of animals under hypoxic conditions, the duration of action potentials can be shortened, and the threshold of ventricular arrhythmia is higher than that of control animals.
(4) It can reduce peripheral vascular resistance and have an anti-aldosterone effect.
(5) This product also has the anti-cardiotoxic effect of doxorubicin and a hepatoprotective effect.
Coenzyme Q10 can be used as an adjuvant therapy for the following diseases:
1. Cardiovascular diseases, such as viral myocarditis and chronic cardiac insufficiency.
2. Hepatitis, such as viral hepatitis, subacute liver necrosis, and chronic active hepatitis.
3. Comprehensive cancer treatment: It can alleviate some adverse reactions caused by radiotherapy and chemotherapy.
Before Taking Coenzyme Q10
Ask your doctor, pharmacist, or another healthcare provider for advice, and let your doctor know in advance if you have
1. High or low blood pressure;
2. Are receiving chemotherapy;
3. Smoking;
4. Coenzyme Q10 is considered Possibly Safe for use during pregnancy. However, if you are pregnant, do not use this product without medical advice.
5. It is not known whether it will pass into breast milk or if it will cause harm to a nursing baby.
Do not use this product without a doctor's advice if you are breastfeeding a baby.
How Much Q10 Should You Take A Day
1. Adult medication: take 10-15mg orally once, three times a day, after meals.
2. Children’s medicine: take 10-20mg orally once, 2-3 times daily. It must be taken under the supervision of an adult and a doctor.
How To Test Coenzyme Q10
1. Chromatographic conditions and system suitability test: Octadecylsilane bonded silica gel is used as filler; methanol-absolute ethanol (1:1) is used as the mobile phase; column temperature is 35°C; detection wavelength is 275nm. Take an appropriate amount of coenzyme Q10 reference substance and coenzyme Q9 reference substance, dissolve and dilute with absolute ethanol to make a mixed solution containing about 0.2mg in each 1ml, take 20μl and inject it into the liquid chromatograph, the peak of coenzyme Q9 and the peak of coenzyme Q10 The resolution should be greater than 6.5, and the number of theoretical plates calculated based on the coenzyme Q10 peak should not be less than 3000.
2.Determination method: Take 20mg of this product, weigh it accurately, add about 40mL of absolute ethanol, shake and dissolve in a 50°C water bath. Let cool, transfer to a 100mL measuring bottle, dilute to the mark with absolute ethanol, Shake well as the test solution, accurately measure 20 μL, inject it into the liquid chromatograph, and record the chromatogram; take another appropriate amount of coenzyme Q10 reference substance, and measure it with the same method. According to the standard external method to calculate the peak area, that is.
How To Pack And Store Q10?
Packaging: export grade sealed drum, vacuum sealed aluminum foil packaging, can also be packed according to customer needs.
Storage: please store in a cool and dry place to avoid bright light and high temperature.
If you want to buy Q10, feel free to contact Xi'an Sonwu.
E-mail: sales@sonwu.com