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Ticarcillin Disodium Powder

Ticarcillin Disodium Powder

Appearance: White or off-white crystalline powder
Specification: 98%
CAS: 74682-62-5
Molecular Formula: C15H14N2Na2O6S2
Molecular Weight: 428.39
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of ticarcillin disodium powder in China. We warmly welcome yuo to wholesale bulk ticarcillin disodium powder for sale here from our factory. Quality products and reasonable price are available.

 

What Class Of Drug Is Ticarcillin Disodium

Ticarcillin disodium powder is a beta-lactam antibiotic belonging to the penicillin family. It is a broad-spectrum antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. This mechanism of action is against a wide range of gram-positive and gram-negative bacteria. As an extended-spectrum penicillin, ticarcillin disodium has an expanded spectrum of activity compared to narrow-spectrum penicillins. It is a semi-synthetic penicillin that is highly effective against Pseudomonas aeruginosa, and the effective rate of clinical treatment of Pseudomonas aeruginosa infection is about 90%. Stable to β-lactamase produced by drug-resistant Pseudomonas aeruginosa but susceptible to destruction by β-lactamase produced by Escherichia coli, Proteus mirabilis, and individual Pseudomonas aeruginosa strains. Combined use with gentamicin and polymyxin has a synergistic effect on Pseudomonas aeruginosa.
Ticarcillin disodium is typically used to treat severe intra-abdominal infections, respiratory tract infections, urinary tract infections, skin and soft tissue infections, and septicemia. It is often used with another antibiotic called clavulanic acid, which helps prevent the breakdown of ticarcillin by certain bacteria enzymes, thereby enhancing its effectiveness. If you are interested in this antibiotic, you can contact Xi'an Sonwu anytime; Xi'an Sonwu can provide you with wholesale ticarcillin disodium.

Ticarcillin Disodium structure

 

Certificate Of Analysis

ANALYSIS

SPECIFICATION

RESULT

Appearance

White or off-white crystalline powder

Conform

Loss on Drying

≤0.2%

0.09%

Solubility

Soluble in water: Easily soluble in water

Conform

Particle Size

100% through 80 mesh

Conform

Boiling Point

768.3ºC at 760 mmHg

Conform

Melting Point

N/A

N/A

Heavy metal

Pb

≤ 5 ppm

Conform

Hg

≤ 1 ppm

Not Detected

Cd

≤ 2 ppm

Not Detected

As

≤ 3 ppm

Conform

Total Microbial Content

1000 CFU/ g

Conform

Assay

98%

98.43%

 

Where To Buy Ticarcillin Disodium

Xi'an Sonwu Biotech Co. Ltd. is a manufacturer and distributor with more than ten years of experience. It has extensive and stable cooperation with countries worldwide in the Americas, Asia, Europe, and Oceania. Xi'an Sonwu has always insisted on product quality first; serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from selecting raw materials and pursuing high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need any API raw materials, please get in touch with Xi'an Sonwu.
Xi'an Sonwu ultimately ensures the product's quality and offers a sample for your test. Here is the quantity.

Ticarcillin Disodium Form

Sample Amount

MOQ

Powder

10g

100g

 

Customers' Good Comment

-401

 

What Is The Mechanism Of Action Of Ticarcillin

The mechanism of action of ticarcillin is interference with the synthesis of the bacterial cell wall, leading to bacterial cell death. Other antibiotics share this mechanism in the penicillin class. Ticarcillin targets enzymes called penicillin-binding proteins (PBPs) involved in cross-linking peptidoglycan chains within the cell wall. PBPs are responsible for synthesizing the peptidoglycan layer of the cell wall, which is essential for the integrity and strength of the cell wall. By inhibiting the action of these PBPs, ticarcillin interferes with the synthesis of the peptidoglycan layer, ultimately leading to the death of the bacterial cell.
Bacterial cells have a unique structure with a rigid cell wall composed primarily of peptidoglycan. Peptidoglycan is a mesh-like structure comprising long chains of alternating N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) molecules cross-linked by short peptide chains. Penicillin-binding proteins (PBPs) are enzymes located on the inner surface of the bacterial cell membrane. These proteins catalyze the transpeptidation reaction, which forms cross-links between the peptide chains of adjacent peptidoglycan strands.
Ticarcillin has a structure similar to penicillin and can bind to PBPs with high specificity. It can form a covalent bond with the active site of PBP, interfering with its ability to catalyze the transpeptidation reaction. It prevents the formation of cross-links between peptidoglycan chains and weakens the integrity of the bacterial cell wall. As ticarcillin inhibits the action of PBPs, the bacterial cell wall becomes structurally compromised. The weakened cell wall cannot withstand the internal pressure exerted by the bacterium, resulting in lysis and death of the bacterial cell.

Mechanism Of Action Of Ticarcillin

 

What Is Ticarcillin Used For

Ticarcillin disodium powder is an antibiotic used mainly to cure bacterial infections caused by sensitive organisms. It belongs to the penicillin class of antibiotics and is classified as broad-spectrum penicillin. Ticarcillin has broad-spectrum activity, which means it is effective against various bacteria.

Here are some of the common uses of ticarcillin:

Respiratory infections: Ticarcillin is often used to treat respiratory diseases such as pneumonia, bronchitis, and lung abscesses. It is practical against gram-negative and gram-positive bacteria commonly associated with these infections.

Skin and Soft Tissue Infections: Ticarcillin can be used to treat infections of the skin and soft tissues, including cellulitis, infected wounds, and abscesses. It is effective against various bacteria that cause these types of conditions.

Urinary Tract Infections: Ticarcillin can treat urinary tract infections (UTIs) caused by susceptible bacteria. It is particularly effective against Gram-negative bacteria commonly associated with UTIs, such as Escherichia coli and Klebsiella.

Urinary Tract Infections

Intra-Abdominal Infections: Ticarcillin is often used to treat intra-abdominal infections, including peritonitis, intra-abdominal abscesses, and conditions associated with appendicitis or diverticulitis. It can target both aerobic and anaerobic bacteria commonly found in the abdomen.

Septicemia: Ticarcillin effectively treats bloodstream infections, known as septicemia or bacteremia. It can combat a wide range of bacteria that cause sepsis, including both Gram-positive and Gram-negative organisms.

Gynecological Infections: Ticarcillin may be used to treat gynecological infections such as pelvic inflammatory disease (PID) or postpartum infections caused by susceptible bacteria.

Bone and Joint Infections: Ticarcillin might be prescribed to treat bone and joint infections, such as osteomyelitis or septic arthritis, caused by susceptible organisms.

Endocarditis Prophylaxis: In some instances, ticarcillin may be used as prophylaxis against infective endocarditis in individuals at high risk, such as those with certain heart conditions or prior history of endocarditis, before undergoing dental or surgical procedures that carry a risk of causing bacteremia.

 

What Are The Side Effects Of The Antibiotic Ticarcillin

Ticarcillin, like any other medication, can cause side effects. Here are some common side effects associated with ticarcillin:

Gastrointestinal Disturbances: Ticarcillin can cause nausea, vomiting, diarrhea, or abdominal pain. These symptoms are generally mild and resolve on their own. However, it is vital to stay well hydrated, and it is also essential to notify your doctor if these side effects become severe or persistent.

Hypersensitivity reactions: Hypersensitivity reactions to ticarcillin can occur but are uncommon. Symptoms of an allergic reaction that may occur include rash, itching, swelling, trouble breathing, or dizziness.

Superinfections: Like other antibiotics, ticarcillin can disrupt the natural balance of bacteria, leading to the growth of resistant bacteria or fungal infections. That can result in new conditions, such as oral thrush or vaginal yeast infections. Consult a doctor provider if you develop symptoms such as white patches in the mouth or vaginal itching.

Superinfections

Blood Disorders: Rarely, ticarcillin can affect blood cells and lead to certain blood disorders, including decreased red blood cell count (anemia), decreased white blood cell count (leukopenia), or reduced platelet count (thrombocytopenia). Contact your doctor provider if you notice symptoms such as unexplained bruising, bleeding, or signs of infection.

Kidney Problems: Ticarcillin can sometimes cause kidney-related side effects, such as elevated creatinine levels or blood urea nitrogen. These side effects are generally reversible and subside after discontinuing the medication. Regular monitoring of kidney function may be necessary during treatment.

Neurological Side Effects: In rare cases, ticarcillin can cause neurological side effects, including confusion, hallucinations, or seizures. If you experience any unusual changes in mental status or seizures, seek medical attention immediately.

 

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

factory

 

Certificate

certifiacte

 

Packaging

packaging

 

Logostics

logistics

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

FAQ

The dosage of ticarcillin disodium can vary depending on several factors, including the type and severity of the infection, the patient's age and weight, kidney function, and individual response to the medication. 

For adults:
The recommended dose for ticarcillin disodium is 3 to 12 grams daily. It can be administered as 1 to 3 grams every 4 to 6 hours.

For children:
The dosing for children is typically based on body weight. The recommended dosage is 100 to 200 mg/kg/day. It can be administered 25 to 50 mg/kg every 4 to 6 hours.

 

If you want to get pure ticarcillin disodium, you can contact Xi'an Sonwu. Click the email then you get high-quality ticarcillin disodium powder.
Email: sales@sonwu.com

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