O 304 Capsules

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of o 304 capsules in China. We warmly welcome yuo to wholesale bulk o 304 capsules for sale here from our factory. Quality products and reasonable price are available.

WHAT IS OS-01 PEPTIDE
O 304 capsules (O-304, OS-01, ATX-304) are one of the available forms of a novel small molecule compound. Its chemical name is N-(2,6-dichlorophenyl)-4-(3-thiazol-2-yl)pyridin-2-amine. The product catalog describes it as a "pan-AMPK activator" (pan-activator of AMP-activated protein kinase, or AMPK), meaning it can activate multiple AMPK isoforms. OS-01 increases AMPK phosphorylation (p-AMPK), thereby enhancing AMPK signaling pathway activity without significantly reducing cellular ATP levels. Consequently, it is being studied for improving glucose metabolism, enhancing fatty acid oxidation, ameliorating insulin resistance, and improving cardiovascular metabolism.
Unlike traditional AMPK activators such as AICAR or metformin, it exhibits greater selectivity and oral bioavailability, and can cross cell membranes to activate the AMPK pathway directly. Therefore, OS-01 has attracted significant attention in metabolic disease and anti-aging research. Xi'an Sonwu can provide raw os 01 o 304 powder. If you want OS-01, contact Xi'an Sonwu.

OS-01 HPLC

Os 01 O 304 Where To Buy

Xi'an Sonwu Biotech Co., Ltd. has rich experience in global trade and the health industry. Insist on faith-based and quality-first as the company's principles. Xi'an Sonwu strictly controls product quality, which means selection begins with raw materials. Besides, Xi'an Sonwu handles every detail and minimizes costs so that customers can get a cost-effective product. Based on this, customers have given very positive feedback on products. So look for Xi'an Sonwu Biotech Co., Ltd. when buying OS-01 powder.

Xi'an Sonwu can ensure product quality, allowing samples to be supplied. Here is the quantity.

Customers's Good Comment

OEM Service

Xi'an Sonwu not only supplies high-quality os 01 o 304 powder but also capsules.
So customers can customize the capsules they want. And items below can be supplied.
Customized capsule shells (material, size, color)
Customized bottles(material, size, color, style)
Customized packaging(vacuum foil packaging, box, drum, in plastic lining steel drums)
Customized label(matte film, optical mask, paint film)

Os 01 o 304 benefits

1. Promotes Fat Burning and Weight Control
O 304 capsules is a pharmacological AMPK activator that directly activates this pathway, independent of exercise or energy deprivation, putting the body into a "post-exercise fat-burning state." Activated AMPK phosphorylates and inhibits acetyl-CoA carboxylase (ACC), thereby reducing malonyl-CoA levels. Several studies have shown that in mice with high-fat diet-induced obesity, OS-01 treatment significantly increases fatty acid oxidation rates, reduces body fat percentage by 15–25%, and substantially reduces hepatic lipid deposition. This approach to fat loss is not about "suppressing appetite" or "depleting fat," but instead alters energy utilization at the cellular level.

2. Improves Insulin Resistance and Blood Glucose Metabolism
In addition to promoting fat burning, another core metabolic benefit is improving insulin resistance and blood glucose metabolism. In type 2 diabetes, obesity, or metabolic syndrome, the body's muscle, liver, and adipose tissue are weakened in their response to insulin signals. To truly improve insulin resistance, it is necessary to restore cellular insulin sensitivity at the level of energy metabolism and signaling. OS-01 is precisely the advantage of it. OS-01 increases skeletal muscle glucose uptake and utilization, improving insulin sensitivity. In type 2 diabetic mice and early clinical studies, it has demonstrated effects on fasting blood glucose and the HOMA-IR index. Its metabolic benefits are similar to those of metformin, but it activates a more direct pathway and has a more comprehensive effect.

3. Improves Basal Metabolism and Energy Expenditure
OS-01 can increase mitochondrial activity and energy flux (a mild uncoupling effect), allowing the body to consume more energy at rest. In studies, it-treated animals exhibited increased oxygen consumption and energy expenditure under the same dietary conditions. It suggests it may mimic the metabolic effects of exercise and offer potential benefits for sedentary or inactive individuals.

4. Improves Cardiovascular and Muscle Metabolic Function
OS-01 improves energy efficiency in the heart and skeletal muscle through multiple mechanisms: AMPK activation, mitochondrial energy metabolism, and microvascular improvements. OS-01 also enhances blood perfusion and anti-inflammatory capacity. OS-01 not only helps improve exercise endurance and burn fat, but also has significant benefits for cardiovascular health and metabolic homeostasis. Experiments in aged mice have shown that it improves cardiac function and slows the decline in exercise capacity. These characteristics suggest that it is not just a "fat burner" but also a potential regulator of systemic metabolic function.

5. Reduces fatty liver and inflammatory responses
OS-01 can reduce hepatic lipid deposition and the expression of adipose-derived inflammatory factors, thereby improving outcomes in non-alcoholic fatty liver disease (NAFLD) models. Activating AMPK can also inhibit the NF-κB inflammatory pathway, thereby reducing chronic metabolic inflammation.

6. Potential anti-aging and longevity effects
The AMPK pathway is closely linked to longevity signals, including SIRT1, mTOR, and FOXO3. OS-01 can enhance mitochondrial function and slow metabolic aging, and is considered an "anti-aging metabolic molecule" by some studies.

What Is The Mechanism Of Action Of Atx 304
O-304's core mechanism is to activate AMP-activated protein kinase (AMPK), the "master switch" enzyme that regulates energy metabolism in the human body. When cells are energy-deficient (ATP levels decrease, AMP levels increase), AMPK is activated, initiating a series of metabolic reactions that include promoting glucose uptake and oxidative energy production; promoting fatty acid β-oxidation and reducing fat synthesis; inhibiting gluconeogenesis and cholesterol synthesis; and enhancing mitochondrial function, improving energy metabolism efficiency. These combined reactions cause the body to "burn energy" rather than "store energy," a metabolic state reminiscent of post-exercise.

Research has shown that it exerts its metabolic and fat-reducing effects through the following pathways: 
Direct AMPK activation
OS-01 significantly increases the phosphorylation level of the AMPK α subunit (p-AMPK), thereby enhancing the activity of energy metabolism pathways.
Promoting glucose utilization
In skeletal and cardiac muscle, it increases the expression and membrane localization of the GLUT4 transporter, enabling cells to more efficiently absorb glucose and oxidize it for energy production rather than storing it as fat. Enhances fatty acid oxidation.
O-304 activates AMPK, inhibiting acetyl-CoA carboxylase (ACC) and reducing malonyl-CoA levels, thereby promoting mitochondrial β-oxidation.
Improves mitochondrial function.
Some studies have shown that OS-01 has a mild "uncoupling" effect, increasing mitochondrial energy flux and mimicking the metabolic state induced by exercise.
Enhanced microvascular perfusion and muscle metabolism.
OS-01 improves skeletal muscle microcirculation, enhancing oxygen and nutrient supply, thereby increasing basal metabolic rate.
In summary, the metabolic effects of it combine the three key characteristics of "exercise mimicry," "energy redistribution," and "insulin sensitization," offering potential therapeutic benefits for obesity and related metabolic diseases.

Factory environment

Xi'an Sonwu Biotech Co.. It's a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in Xi'an City's Hi-Tech Industrial Zone, Shaanxi province, China. It pays close attention to the development, research, and production of food additives, plant extracts, APl, and other ingredients for health care products. Xi'an Sonwu supplies five types of raw materials: Anti-hair-loss Powders, Nootropics, APIs, Muscle-Building products, and Plant Extracts. Xi'an Sonwu sincerely believes that the foundation of excellent cooperation lies in providing the best service and high quality. So, welcome your inquiry.

Certificates

Packaging

Logistics

In addition to guaranteeing the product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supply all kinds of couriers according to different needs.

FAQ

Research Use Only

OS-01 is currently used as a research compound only and has not been approved by any national drug or food regulatory agency for human use or as a dietary supplement.

Clinical Phase

OS-01 is being studied only in early-phase clinical trials (Phase IIa) in patients with type 2 diabetes or metabolic syndrome.

Clinical use is strictly controlled, with dose and frequency defined by the study protocol.

If you want to buy O 304 capsules or are interested in Xi'an Sonwu, or have other questions about the product, do not hesitate to contact Xi'an Sonwu.

Email: sales@sonwu.com

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