ATX-304 Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of atx-304 powder in China. We warmly welcome yuo to wholesale bulk atx-304 powder for sale here from our factory. Quality products and reasonable price are available.

What Is ATX-304

ATX-304 Powder (earlier codenamed O-304) is an orally active, full-strength dual AMPK and mitochondrial activator developed by Amplifier Therapeutics/Cambrian Bio. It activates the cellular energy-sensing pathway AMPK (5′-AMP-activated protein kinase) and promotes mitochondrial bioenergetics, improving cellular energy homeostasis and insulin signaling. In animal trials, this has shown a variety of metabolic effects, such as a notable decrease in blood sugar, an improvement in insulin sensitivity, an increase in fatty acid oxidation, a decrease in hepatic fat storage, and an improvement in cardiovascular function.

Originally developed in a collaboration between Betagenon AB in Sweden and the Karolinska Institutet, this molecule was incorporated into Amplifier Therapeutics' aging and metabolic disease pipeline. It is currently being studied for the treatment of type 2 diabetes, obesity, heart failure, renal metabolic damage, and age-related metabolic decline. Studies have shown that ATX-304 has synergistic potential when combined with GLP-1 receptor agonists (such as semaglutide) by enhancing mitochondrial energy metabolism in skeletal muscle, myocardium, and liver.

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Where To Buy

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you want to buy O-304 capsules.

Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.

Customers' Good Comment

OEM Service

Xi'an Sonwu not only can supply high-quality ATX-304 powder but also supply O-304 capsules.

So any customers could customize the capsules they want. And items below can be supplied.

1. Customized capsules shells (size, color, material)

2. Customized bottles(size, color, material, style)

3. Customized packaging(vacuum foil packaging, box, drum)

4. Customized label(paint film, matte film, optical mask)

How ATX-304 Works

ATX-304 works by activating AMPK (AMP-activated protein kinase) and enhancing mitochondrial function, two key systems that control how the body uses and stores energy. It is a pan-AMPK activator and mitochondrial enhancer designed to restore cellular energy balance in metabolic and cardiovascular diseases. It binds to AMPK and maintains its phosphorylation at the Thr172 site, preventing deactivation by phosphatases. This sustained activation of AMPK shifts metabolism toward energy consumption rather than storage - stimulating fatty acid oxidation, glucose uptake, and ATP production in skeletal and cardiac muscle, while suppressing lipid synthesis, gluconeogenesis, and inflammation in liver and adipose tissue.

At the same time, ATX-304 enhances mitochondrial biogenesis and respiration, which lowers oxidative stress and boosts cellular energy efficiency. increased insulin sensitivity, decreased body fat, increased energy metabolism in the heart and kidneys, and general metabolic protection are the results of these combined benefits.Because of this dual mechanism, ATX-304 is being developed as a potential therapy for type 2 diabetes, obesity, heart failure, and age-related metabolic decline.

Does Ampk Help With Weight Loss

Yes-AMPK (AMP-activated protein kinase) plays a central role in weight loss and metabolic regulation, but its mechanism of action depends on what activates it and where it acts in the body. Here's a clear breakdown:

AMPK (5′-AMP-activated protein kinase) is a key "metabolic switch" that regulates energy metabolism in the body and plays a central role in weight control and fat metabolism. It's an enzyme that becomes activated when your body senses low cellular energy (for example, during exercise, fasting, or calorie restriction). Once activated, AMPK helps restore energy balance by:
Increasing energy production
Promoting fatty acid oxidation (burning fat for energy)
Enhancing glucose uptake by muscles
Boosting mitochondrial activity and improving cellular efficiency
Reducing energy storage
Inhibiting fat synthesis (lipogenesis)

Inhibiting cholesterol and triglyceride synthesis in the liver
Downregulating gluconeogenesis (producing glucose from non-carbohydrate sources)

When the body is low on energy, as occurs during exercise, fasting, or calorie restriction, AMPK is activated. This promotes fatty acid oxidation, glucose absorption, and mitochondrial energy production while suppressing energy storage mechanisms such as lipogenesis, gluconeogenesis, and cholesterol synthesis. AMPK's activation can change metabolism from storage to burning, which can
Boost the burning of fat, especially in the liver and skeletal muscles.
Reduce the buildup of fat
Boost energy expenditure and insulin sensitivity

Through this metabolic reprogramming from storage to consumption, AMPK effectively increases energy expenditure and reduces fat accumulation, ultimately improving insulin sensitivity and metabolic efficiency. Numerous studies have shown that sustained AMPK activation can help reduce weight, visceral fat, and lower blood sugar and lipid levels. It is also one of the primary targets of drugs such as metformin and berberine and novel metabolic modulators such as ATX-304. Therefore, AMPK activation is considered a key molecular mechanism for achieving healthy fat loss and metabolic balance.
 

What Are The Side Effects Of Ampk Activators

AMPK activators can offer strong metabolic benefits, but like all bioactive compounds, they may also cause side effects, depending on how strongly and where AMPK is activated, and what kind of activator is used (natural vs synthetic).

Because AMPK activation shifts the body from energy storage to energy consumption, excessive or systemic activation can sometimes cause fatigue, hypoglycemia (low blood sugar), gastrointestinal discomfort, or muscle weakness, especially if energy stores drop too low.
In the liver, chronic overactivation may suppress lipid synthesis too strongly, leading to dry skin or hormonal imbalances (since cholesterol is a hormone precursor).
Some strong pharmacological AMPK activators-such as AICAR or experimental molecules like ATX-304-can cause nausea, flushing, mild hypotension (low blood pressure), or elevated lactate levels due to enhanced glycolytic metabolism.

On the other hand, natural AMPK activators like metformin or berberine tend to have milder side effects, typically digestive upset or diarrhea, which often improve with time. In rare cases, very high or unregulated AMPK activation could interfere with muscle growth or fertility signaling, since AMPK temporarily inhibits anabolic (growth-promoting) pathways like mTOR.

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

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Package

Logistics Update

In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

Company's Profile

Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry if you want O-304 capsules.

And if you want to know the ATX-304 Powder price, please contact XI'an Sonwu.

Email: sales@sonwu.com

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