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Mobic Powder

Mobic Powder

Appearance: Off-White To Pale Yellow Crystalline Powder
Specification: 99%
CAS: 71125-38-7
Molecular Formula: C14H13N3O4S2
Molecular Weight: 351.401
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of mobic powder in China. We warmly welcome yuo to wholesale bulk mobic powder for sale here from our factory. Quality products and reasonable price are available.

 

Meloxicam
Mobic powder, or meloxicam, is a nonsteroidal antipyretic, analgesic, and anti-inflammatory drug. It is not derived from natural products but is prepared by chemical synthesis. It is not a hormone drug but has potent anti-inflammatory, analgesic, and antipyretic effects. It can selectively inhibit the activity of cyclooxygenase-2 (COX-2), thereby blocking the synthesis of prostaglandins. The inhibitory effect on the biosynthesis of prostaglandins in the inflammatory site is stronger than the biosynthesis of prostaglandins in the gastric mucosa or kidneys, and it is safer than other NSAIDs. It is mainly used to relieve the symptoms of osteoarthritis, painful osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. This medication typically reaches peak plasma concentration 4 to 5 hours after oral administration and has oral solid bioavailability (89%). Its half-life is about 15 to 20 hours long, making it suitable for a once-daily dosing regimen. The liver mainly metabolizes meloxicam, and metabolites are excreted through urine and feces. As the safety research of NSAID drugs deepens, the application of mobic may be further optimized. For example, by developing more selective COX-2 inhibitors, gastrointestinal and cardiovascular side effects can be reduced. In addition, developing new drug delivery systems may improve their efficacy and patient compliance. As you can see, it is very productive and safe, so if you need raw meloxicam powder, Xi'an sonwu can provide it.

Meloxicam structure

 

Certificate Of Analysis

Analysis Item

Specification

Test results

Appearance

Off-white to pale yellow crystalline powder

Light yellow powder

Solubility

Meets the requirements

Meets the requirements

Identification

A: Infrared spectrum should conform

Conforms

B:Should conform

Conforms

Specific rotation

+58°~+64°

+61°

Loss on drying

≤3.0%

2.3%

pH

4.5~6.5

5.0

Moisture(water) content

≤6.0%

4.6%

Absorbance

≤0.2%

Conforms

Absorbance index

360~390

Conforms

Assay of Cefotaxime

(calculated on the dried basis)

≥95%

99%

Any individual impurity

≤1.0%

0.38%

Sum of all impurities

≤3.0%

1.4%

Bacterial endotoxins

≤0.2USP EU/mg

<0.2USP EU/mg

Sterility

Meets the requirements

Meets the requirements

 

Where To Buy Meloxicam For Humans
Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. Xi'an Sonwu has established solid and reliable partnerships with countries in America, Asia, Europe, and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to meet their needs fully.
High-quality products are Xi'an Sonwu's top priority, and the company's dedication to perfection is seen in all aspects of its operations, including the selection of raw materials, manufacturing processes, sample testing, and staff professionalism. By meticulously managing every detail, Xi'an Sonwu can minimize costs without compromising quality, ensuring customers receive products of exceptional value.
Xi'an Sonwu is proud of the positive feedback it has received from customers, who have consistently recognized the quality of the products. To further prove product confidence, Xi'an Sonwu will provide samples for you to test.

Form

Sample Amount

MOQ

Powder

1kg

1kg


Customers' Good Comment

Customers' Good Comment

 

What Is Meloxicam Used For
1. Analgesic effect
Like other nonsteroidal anti-inflammatory medicines, it is mainly used for mild to severe persistent dull pain, such as neuralgia, joint pain, etc. Specifically, it has demonstrated a solid and long-lasting analgesic impact in rat studies on inflammatory pain. In male rats with experimental RA, it was administered at a dose of 0.063-0.5 mg kg-1. During the experiment, it was adequate for the redness and swelling of the rat's hind paws and bone and cartilage damage. It had a solid and lasting analgesic effect on inflammatory pain. During this experiment, it had no impact on the central nervous system. Similar to indomethacin, it has no analgesic effect on visceral pain.

 

2. Antipyretic effect
Meloxicam can reduce the body temperature of fever patients but has almost no effect on average body temperature. For example, within the anti-inflammatory dose range, it does not impact the average body temperature of rats but can reduce yeast-induced fever. Mobic was used in rats with fever-causing toxins in their bodies, and it was found that it had a significant cooling effect twice a week.

meloxicam Analgesic effect

 

3. Anti-inflammatory effect
In animal inflammation models (mainly including carrageenan and white clay-induced rat hind paw edema model, cotton ball-implanted rat granuloma model, carrageenan-induced pleurisy and liquid paraffin-adjuvanted Mycobacterium tuberculosis-induced arthritis model), mobic showed anti-inflammatory solid activity. For carrageenan-induced pleurisy, it can reduce pleuritic secretion and inhibit leukocyte migration. In rat pleurisy, it inhibits the biosynthesis of prostaglandin E2 (PGE2), and the inhibitory effect is two times that of piroxicam and eight times that of diclofenac. In mouse peritonitis, the inhibitory effect of it is two times that of piroxicam and more than ten times that of diclofenac.
In terms of medication dosage, male mice with experimental RA were given mobic, piroxicam, and diclofenac to see how they affected the mice's hind paw swelling, bone and cartilage damage, increased weight in the spleen, erythrocyte sedimentation rate, and changes in the composition of serum proteins. It was found that the above drugs all had the same inhibitory effect on the swelling of the mouse's hind paws and the swelling of the mouse's hind paws caused by secondary reactions. The dose of piroxicam was twice that of it, while the doses of diclofenac and tenidap were 3.5 and 60 times that of meloxicam, respectively. The daily dose of it required to inhibit bone and cartilage damage caused by RA is lower, and piroxicam is four times that of mobic.

 

Is Meloxicam A Lot Stronger Than Ibuprofen
Strength and Efficacy
Mobic powder is generally considered more potent and longer-acting than ibuprofen. It has a higher affinity for COX-2 inhibition, which may reduce inflammation more effectively and cause fewer gastrointestinal side effects than non-selective NSAIDs such as ibuprofen. Ibuprofen is effective for treating mild to severe pain and inflammation.
Duration of Action
Because it has a longer half-life (15–20 hours), once-daily dosing is possible, which could increase patient convenience and compliance. On the other hand, ibuprofen has a shorter half-life (2-4 hours) and typically requires multiple daily dosing (every 4-6 hours).
Selectivity for COX Enzymes
Mobic is more selective for COX-2, meaning it preferentially inhibits the COX-2 enzyme, which is involved in inflammation, and may cause fewer gastrointestinal side effects than non-selective NSAIDs. Ibuprofen inhibits both COX-1 and COX-2 enzymes. COX-1 inhibition increases the risk of gastrointestinal problems such as ulcers and bleeding.
Use Cases
Due to its long-lasting effects and the convenience of once-daily dosing, it is often used to treat chronic conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. At the same time, ibuprofen relieves acute pain such as headaches, menstrual cramps, toothaches, and minor injuries. It is also used to reduce fever.

Meloxicam vs Ibuprofen

 

Meloxicam Mechanism Of Action
Meloxicam is a nonsteroidal anti-inflammatory drug. Nonsteroidal anti-inflammatory medications work by blocking cyclooxygenase, which stops the production of pro-inflammatory prostaglandins.
Arachidonic acid undergoes hydrolysis to prostaglandin G2, which is further reduced to PGH2, thanks to the action of cyclooxygenase, a glycoprotein and serum protein that is membrane-bound. COX has two isomers: cyclooxygenase-1-structural enzyme and cyclooxygenase-2-PGG2 inducible enzyme. The inducible enzyme COX-2 is induced by inflammatory regulation and regulates inflammatory response. The structural enzyme COX-1 is necessary for normal physiological processes and exists in most tissues. Its function is to synthesize PG to regulate the regular physiological activity of cells, protect the gastrointestinal mucosa, support microcirculation in the kidneys, and protect other organs from damage. Among many different nonsteroidal anti-inflammatory drugs, it selectively inhibits COX-2, while diclofenac, piroxicam, indomethacin, and other nonsteroidal anti-inflammatory medicines either inhibit both COXs or inhibit COX-1 more strongly than COX-2. Mobic has good gastrointestinal safety and low renal toxicity, all due to its weak ability to inhibit COX-1.

Meloxicam Mechanism Of Action

 

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture, and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

factory


Certificates

certificates

 

Packaging

packaging

 

Logistics

Logistics

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

courier

 

FAQ
1. Strong Strength
Xi'an Sonwu owns a producing workshop, OEM factory, and lab.
2. Experienced
Doing export business all over the world for more than ten years.
3. Professional team
Xi'an Sonwu has a perfect R& sales and service team.
4. Sincere Service
Xi'an Sonwu has a perfect R& sales and service team. Xi'an Sonwu has been in the industry for many years, and the customer praise rate has reached 99%.
5. Customers' review
Xi'an Sonwu has been in the industry for many years, and the customer praise rate has reached 99%.

If you want to know the meloxicam powder price, you can contact Xi'an Sonwu. Click the email, and then you get high-quality mobic powder.
Email: sales@sonwu.com

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