Mirabegron Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of mirabegron powder in China. We warmly welcome yuo to wholesale bulk mirabegron powder for sale here from our factory. Quality products and reasonable price are available.

What Is YM178 Generic

Mirabegron powder, studied as YM178 and sold under Myrbetriq, is a pharmaceutical compound used primarily to treat overactive bladder (OAB). Millions of people worldwide suffer from this illness, which is typified by symptoms like urge incontinence, sudden and uncontrollable urges to urinate, and frequent urine. YM178 belongs to a class of drugs called beta3-adrenergic agonists, which target beta3-adrenergic receptors in the bladder. By activating these receptors, the detrusor muscle of the bladder relaxes, thereby increasing its ability to hold urine and reducing urgency and frequency. It is fairly well absorbed in the body, with an estimated bioavailability of 35% at standard doses. After administration, peak plasma concentrations (Cmax) are typically reached within 3-5 hours. Metabolism occurs primarily through multiple pathways, including hydrolysis and oxidation, with the cytochrome P450 system playing a minor role. This diverse metabolic pathway reduces the potential for significant drug-drug interactions.

Since its launch, YM178 has undergone several studies that have confirmed its effectiveness for OAB and explored its potential applications in related urological conditions such as neurogenic bladder and benign prostatic hyperplasia (BPH). Emerging studies are investigating Mirabegron's potential to treat other conditions associated with smooth muscle dysfunction, such as irritable bowel syndrome (IBS) and various gastrointestinal disorders. So, as you can see, its application range is very wide. If you need raw YM 178 powder, Xi'an Sonwu can provide it.

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Mirabegron YM178 For Sale

Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. It has established strong and reliable partnerships with countries in America, Asia, Europe and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to fully meet their needs.

Starting from carefully selecting raw materials, every step of the Xi'an Sonwu production process is strictly controlled. Xi'an Sonwu places a high premium on product quality, which is demonstrated in every aspect of the business's operations, including sample testing, manufacturing technology, material selection, and employee professionalism. Xi'an Sonwu can ensure that customers obtain items worth their money by meticulously regulating every detail and minimizing expenses without sacrificing quality.

Customers who consistently acknowledge the high caliber of the items give Xi'an Sonwu positive reviews, which makes them proud. Xi'an Sonwu will provide you with samples to test and further demonstrate their confidence in the goods.

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What Is Medicine Mirabegron Used For

1. Overactive Bladder (OAB)

Urgency incontinence, abrupt and intense urge to urinate, and frequent urine are some of the signs of overactive bladder (OAB), a common bladder dysfunction. Uncontrolled contraction of the bladder's detrusor, which results in the bladder producing premature urine signals, is typically the cause of these symptoms. This symptom greatly impacts the patient's quality of life, especially in daily activities and nighttime sleep, often leading to embarrassment and social isolation.

Mirabegron powder is mainly use for OAB, which is used to relieve bladder problems caused by urgency, frequent urination, and urgency incontinence. YM 178 activates the β3 adrenergic receptors in the bladder and relaxes the muscles, increasing bladder capacity and reducing urgent and frequent urination.

2. Symptoms related to Benign Prostatic Hyperplasia (BPH)

Benign Prostatic Hyperplasia is a common male disease that increases with age, mainly manifested by an enlarged prostate, which affects the urethra and causes a range of urinary tract symptoms. BPH does not cause disease, but its symptoms can seriously affect the quality of life. BPH is caused by the proliferation of prostate tissue, which compresses the bladder outlet through the urethra, resulting in impaired urine flow. The incidence of BPH increases significantly with age, especially in men over 50 years old.

Preliminary studies show that it may be effective for patients with benign prostatic hyperplasia with symptoms of frequent urination and urgency, especially for those who do not respond well to traditional medications or cannot tolerate side effects. Mirabegron relieves bladder pressure through the same mechanism of action, which may relieve urinary symptoms in male BPH patients.

3. Neurogenic bladder

A neurogenic bladder occurs when the neurological system is damaged or diseased, resulting in aberrant bladder function. Usually brought on by nerve damage or illness, this condition affects the normal function of urination by causing problems with bladder control during pee storage and urination.

Some studies are exploring the effect of mirabegron on patients with neurogenic bladder. The bladder activity of such patients is unstable or uncontrolled due to nerve damage, and it may improve the symptoms of such patients through its effect of relaxing the bladder.

4. Stress urinary incontinence (SUI)

Stress urinary incontinence (SUI) is a common type of urinary incontinence. It usually refers to the inability to control the discharge of urine when abdominal pressure increases. Common triggers include coughing, sneezing, laughing, exercising or lifting heavy objects. The most common type of urine incontinence in women, especially those who have recently given birth, is stress urinary incontinence. Some males may also be affected, particularly those who have had prostate surgery.

Although mirabegron is not directly used for stress urinary incontinence, in some cases, it may be used to relieve accompanying OAB symptoms such as urgency. Studies have shown that the combination of YM 178 and anticholinergic drugs may be more effective for patients with both OAB and SUI.

What Are The Most Common Side Effects Of Mirabegron

1. High Blood Pressure

One of the most common side effects of mirabegron is increased blood pressure. Research has indicated that some patients may notice mild elevations in their systolic and diastolic blood pressure when using this drug.

2. Headache

Headache is another common side effect of YM 178. This side effect is usually mild but can be bothersome for some patients. Always consult a healthcare provider if headaches persist or worsen.

3. Dry Mouth

YM 178 is one of the drugs that frequently causes dry mouth as a side effect. While the symptoms of dry mouth are less noticeable than with older medications, such as anticholinergics, it can still cause discomfort for some users.

4. Constipation

5. Urinary Tract Infection (UTI)

6. Fatigue

7. Palpitations or increased heart rate

Factory

1. Xi'an Sonwu Biotech Co., Ltd has a factory to produce, manufacture and store the products, so it has adequate stock. Xi'an Sonwu has a well-ordered, clean and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.

2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

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Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ

The recommended dose of mirabegron for treating overactive bladder (OAB) symptoms is usually 25 mg once daily. After 4 to 8 weeks, this dose can be increased to 50 mg once daily, depending on the patient's response to treatment and tolerance of the medication. The 50 mg dose is the maximum recommended daily dose​.

If you want to know the YM 178 powder price, you can contact Xi'an Sonwu. Click the email, and then you get high-quality mirabegron powder.

Email: sales@sonwu.com

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