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Methylene Blue Powder

Methylene Blue Powder

Appearance: Dark green crystalline powder
Specification: 98% min
CAS: 61-73-4
Molecular Formula: C16H18N3ClS
Molecular Weight: 319.85
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package, Capsules)

Product Introduction

What Is Methylene Blue

Methylene blue powder is referred to as MB and is also called methylthioninium chloride powder. It is a synthetic dye with the chemical name methylthioninium aniline and the chemical formula of C16H18N3ClS. It is a phenothiazine salt with a dark green bronze luster crystal or powder. It is soluble in water and ethanol but insoluble in ethers. MB is relatively stable in the air, and its aqueous solution is alkaline and toxic. It was originally used as a dye in the textile industry and later gradually gained application in the medical field. It has antioxidant, antibacterial, and antiviral properties and is often used to stain tissue samples and bacteria for observation under a microscope. In addition, it can be used as a drug in some cases. Due to its unique chemical properties and multifunctional uses, MB is very important in many fields, such as laboratories, medical care, and industry. If you need Methylene blue, Xi'an Sonwu can supply it. Xi'an Sonwu is looking forward to hearing from you.

Methylene blue MF

 

Certificate Of Analysis

ANALYSIS

SPECIFICATION

RESULT

Appearance

Dark green crystalline powder

Complies

Assay (as is Basis)

80~85%

80.98%

Assay on dry basis

98%~103%

98.22%

Loss on drying (at 110℃)

8~16%

10.18%

Residue on ignition

<1.2%

0.46%

Absorptivity 1%, 1cm, at Max.663.0nm

2200~2700

2258

Sulphated ash

<1.0%

0.61%

Zinc content

<100ppm

82ppm

Solubility

Clear blue solution

Complies

Residual solvent

Nil

Nil

Aluminum

<100ppm

20ppm

Cadmium

<1ppm

N.D

Chromium

<10ppm

2ppm

Copper

<100ppm

76ppm

Tin

<10ppm

2ppm

Iron

<100ppm

69ppm

Manganese

<10ppm

4ppm

Mercury

Nil

Nil

Molybdenum

<10ppm

2ppm

Nickel

<10ppm

3ppm

Lead

<10ppm

1ppm

Arsenic

<8ppm

2ppm

Chrmatographic purity

Passes tests

Passes

 

Where To Buy Methylene Blue

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce costs to the maximum so our customers can get cost-effective products. Based on these, customers have given a lot of good feedback about our products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying methylene blue.

Xi'an Sonwu ensures product quality and can provide samples. Here is the quantity.

Methylene Blue Form

Sample Amount

MOQ

Powder

1kg

1kg

Bulk Capsules

2000 capsules

2000 capsules

Bottle Capsules

10 bottles

10 bottles

 

Customers' Good Comment

-901

 

OEM Service

Xi'an Sonwu can supply high-quality methylene blue capsule and powder.

So customers can customize the capsules they want. The items below can be supplied.

Customized capsule shells (size, color, material)

Customized bottles(size, color, material, style)

Customized packaging(vacuum foil packaging, box, drum)

Customized label(paint film, matte film, optical mask)

Methylene Blue OEM service

 

Methylene Blue Benefits

Methylene blue powder is a synthetic compound with a wide range of benefits in medical, therapeutic, and research applications, largely due to its unique antioxidant, antimicrobial, and cellular protective properties. Here's a summary of its primary benefits:

1. Antioxidant and Mitochondrial Support

MB supports mitochondrial function by promoting cellular energy (ATP) production and reducing oxidative stress. This property has led to its use in studies focused on neuroprotection, cognitive enhancement, and aging.

Its antioxidant capacity is also believed to mitigate cellular damage from free radicals, which benefits overall cellular health.

2. Neuroprotective Benefits

Due to its ability to improve mitochondrial efficiency, it is being researched for its potential in cognitive enhancement and neuroprotection. Early studies suggest it may help in conditions like Alzheimer's disease and other forms of dementia, as it can reduce amyloid and tau protein aggregations, which are implicated in neurodegenerative diseases.

Some studies have shown that low doses of it can enhance memory and cognitive performance.

3. Antimicrobial Properties

MB has strong antimicrobial and antifungal properties, which makes it effective in treating certain infections. It has historically been used as an antimalarial agent and is effective against some bacteria and viruses.

Its antimicrobial properties are sometimes used in wound treatment and urinary tract infections, as it can help eliminate harmful pathogens.

4. Methemoglobinemia Treatment

MB is an FDA-approved treatment for methemoglobinemia, a condition where hemoglobin cannot effectively release oxygen to body tissues. It works by converting methemoglobin back to normal hemoglobin, improving oxygen delivery in the body.

MB Methemoglobinemia Treatment

5. Mood and Cognitive Effects

Emerging research suggests MB at low doses may have mood-enhancing effects due to its influence on neurotransmitters. Its neuroprotective effects on cells and potential enhancement of mitochondrial function could improve mood and resilience to stress.

6. Potential for the treatment of diseased cell populations

Some studies have shown that MB may selectively target diseased cells under certain conditions. Although it is not yet a standard treatment for diseased cell populations, ongoing studies examine its potential in photodynamic therapy and other treatments.

7. Application in Medical Imaging

It is used in surgical procedures as a dye to highlight tissues, aiding in identifying lymph nodes, tumors, and other anatomical features. This is particularly valuable in breast cancer surgery and other oncology-related surgeries.

Application in Medical Imaging

Safety and Dosage Considerations

It is generally safe at low doses under medical supervision, but higher doses or inappropriate use can lead to toxicity. It's important to consult a healthcare provider before using methylene blue for therapeutic purposes, as individual health status and medications can impact its safety and effectiveness.

 

What Foods Should You Avoid When Taking Methylene Blue

When taking methylene blue, it's important to avoid certain foods that can increase the risk of adverse effects, particularly foods high in tyramine. MB can act as a weak monoamine oxidase (MAO) inhibitor, which can interfere with the breakdown of tyramine, a compound found in various foods. High levels of tyramine can lead to dangerous spikes in blood pressure, especially in people taking MAO inhibitors.

Here are some foods to avoid or limit:

1. Aged, Fermented, or Pickled Foods

Cheese (especially aged cheeses like blue cheese, Parmesan, cheddar, Gouda)

Fermented meats (salami, pepperoni, aged sausages)

Fermented vegetables (sauerkraut, kimchi, pickles)

Aged Fermented or Pickled Foods

2. Cured and Processed Meats

Smoked, aged, or cured meats (bacon, ham, hot dogs, jerky)

Processed deli meats (bologna, pepperoni, salami)

3. Soy Products and Fermented Legumes

Soy sauce, miso, tempeh, and tofu (these can be high in tyramine)

Fermented beans, like certain types of black bean paste

4. Alcoholic Beverages

Red wine, beer (especially tap and home-brewed beer), and sherry are particularly high in tyramine.

Other alcoholic beverages can also interact with it and should be avoided or used with caution.

5. Overripe Fruits and Certain Vegetables

Overripe bananas, avocados, and figs contain tyramine.

Some people may also be advised to limit broad beans (fava beans) as they can have high tyramine levels.

6. Certain Condiments and Sauces

Soy sauce, teriyaki sauce, and other fermented sauces are typically high in tyramine.

Fish sauces and shrimp paste should also be used with caution.

Certain Condiments and Sauces

Other Considerations

Caffeine: It's wise to limit caffeine intake, as it can increase blood pressure and may compound the stimulatory effects of MB on the nervous system.

Chocolate contains small amounts of tyramine, so it may need to be limited if you are taking higher doses of it.

Since MB can interact with many drugs and foods, it's best to follow your healthcare provider's guidance to avoid any potential complications.

 

Methylene Blue Side Effects

MB is generally safe when used in controlled, low doses for approved medical purposes but can cause various side effects. Some side effects are mild, while others can be more serious, especially at higher doses or in people with specific health conditions.

Common Side Effects

1. Discoloration of Urine and Stool: It often causes a blue or green tint in urine and stool, which is harmless but noticeable.

2. Skin and Mucous Membrane Discoloration: Skin, mouth, and even the whites of the eyes may temporarily turn blue or green after methylene blue use.

Skin and Mucous Membrane Discoloration

3. Gastrointestinal Symptoms: Common symptoms include nausea, vomiting, abdominal pain, and diarrhea.

4. Headache and Dizziness: Some users may experience headaches, dizziness, or lightheadedness, especially after higher doses.

Serious Side Effects

1. Serotonin Syndrome: It can act as a weak monoamine oxidase inhibitor (MAOI), increasing serotonin levels. When combined with other serotonergic drugs (e.g., SSRIs, SNRIs, or certain antidepressants), it can cause serotonin syndrome. This is a potentially life-threatening condition marked by symptoms like confusion, agitation, fever, muscle rigidity, and rapid heart rate.

2. Hemolytic Anemia in G6PD Deficiency: People with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid it, as it can lead to hemolytic anemia-a rapid breakdown of red blood cells.

3. Breathing Problems: At high doses, It can interfere with normal oxygen delivery in the body, potentially leading to respiratory distress.

4. High Blood Pressure: It can increase blood pressure, especially with foods high in tyramine or certain medications.

High Blood Pressure

5. Allergic Reactions: In rare cases, it may cause an allergic reaction, with symptoms like rash, itching, swelling (especially of the face or throat), severe dizziness, and difficulty breathing.

Neurological Effects

Some people may experience confusion, restlessness, or agitation. Very high doses may lead to tremors or other neurological symptoms.

Other Potential Side Effects

1. Skin Sensitivity: Some people may develop sensitivity to light after taking it.

2. Muscle Pain: High doses may cause muscle aches or cramping in some cases.

It's important to only use MB under the guidance of a healthcare provider. They can help manage and monitor any side effects, especially if you have underlying health conditions or are taking other medications.

 

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

factory a

factory b

 

Certificate

certificates

 

Packing

packaging

 

Logistics Update

-902

In addition to guaranteeing product quality, the other most vital thing is that clients receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

FAQ

1. How to inquire?

We can be reached by phone, email, or social media.

2. How do you guarantee the quality of products?

Each batch must be tested, and COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We cooperate with third parties as well, like SGS.

3. How do you pack and store?

Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.

Storage: You can keep it in a dry and cool place and make it avoid sunlight.

If you want to know about the methylene blue powder and capsules, you can contact Xi'an Sonwu. Click the email, and then you get high-quality methylthioninium chloride powder and capsules.

Email: sales@sonwu.com

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