Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of halofuginone powder in China. We warmly welcome yuo to wholesale bulk halofuginone powder for sale here from our factory. Quality products and reasonable price are available.
What Is Halofuginone
Halofuginone Powder is a compound that belongs to the class of chemicals known as alkaloids. It is derived from Dichroa febrifuga, traditionally used in Chinese medicine for its antimalarial and anti-inflammatory properties. This powder is a synthetic form of this natural compound primarily used for research.
Halofuginone has been studied extensively for its potential pharmacological effects and has shown promise in various areas. Its mechanisms of action include inhibiting certain enzymes and signaling pathways that play a role in cellular processes. One of its critical uses of it is its ability to inhibit collagen synthesis, leading to its investigation into fibrotic disorders.
Due to its anti-fibrotic properties, it has been explored as a potential therapeutic agent for conditions such as liver fibrosis, scleroderma, and systemic sclerosis. Therefore, with extensive research by the medical community, this pharmaceutical intermediate has become a star product of various large suppliers. What can attract customers is the quality of the product. We can provide the raw powder with a purity of not less than 98% and the most favorable price. If you want to know more about it, contact Xi'an Sonwu Biotech Co., Ltd.
Certificate of Analysis
|
ANALYSIS |
SPECIFICATION |
RESULT |
|
Appearance |
White or off-white powder |
Complies |
|
Assay |
NLT 98.0% |
98.24% |
|
Identification |
Characteristic |
Characteristic |
|
Solubility |
DMSO: 9 mg/mL (21.70 mM) |
Complies |
|
Residue On Ignition |
≤0.1% |
0.03% |
|
Loss on drying |
≤2.0% |
0.63% |
|
Heavy metal |
≤15ppm |
<3.5ppm |
|
Cadmium(Cd) |
≤1ppm |
Complies |
|
Lead(Pb) |
≤2ppm |
<0.08ppm |
|
Arsenic(As) |
≤1ppm |
Complies |
|
Mercury(Hg) |
≤0.5ppm |
Not detected |
|
Total bacteria count |
≤1000cfu/g |
Complies |
|
Fungi |
≤100cfu/g |
13cfu/g |
|
Samonella |
Negative |
Not detected |
|
E. Coli |
Negative |
Not detected |
|
Conclusion |
This product complies with international standards. |
|
Where To Buy Halofuginone
Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company’s principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum so our customers can get a cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying Halofuginone.
Xi'an Sonwu ensures the products' quality so that samples can be supplied. Here is the quantity.
|
Form |
Sample Amount |
The Minimum of Quantity |
|
Powder |
5g |
10g |
|
Bulk Capsules |
200 capsules |
200 capsules |
|
Bottled Capsules |
5 bottles |
5 bottles |
Customers' Good Comment
OEM Service
Xi'an Sonwu not only can supply high-quality Halofuginone Powder but also supply its capsules.
So any customers could customize the capsules they want. And items below can be supplied.
1. Customized capsules shells (size, color, material)
2. Customized bottles(size, color, material, style)
3. Customized packaging(vacuum foil packaging, box, drum)
4. Customized label(paint film, matte film, optical mask)
What Is The Mechanism of Action of Halofuginone
The mechanism of action of Halofuginone involves its interaction with various cellular pathways and processes. Here is a summary of its fundamental tools:
1. Collagen union restraint hinders the movement of a catalyst called prolyl-tRNA synthetase engaged with collagen amalgamation. By obstructing this compound, it diminishes the creation of collagen. This component is vital in fibrotic messes, where unnecessary collagen amassing can reduce organ capability.
2. TGF-β flagging regulation: Changing development factor-beta (TGF-β) is a significant flagging pathway in tissue fix and fibrosis. Halofuginone disrupts TGF-β announcing, repressing the Smad flagging pathway and decreasing the declaration of essential fibrogenic qualities. This regulation forestalls fibrotic changes and unfavorable tissue redesigning.
3. Immune modulation has immunomodulatory effects, primarily on T cells (Tregs). It inhibits Th17 cell differentiation and promotes the expansion and function of Tregs. This component might apply to immune system problems and fiery circumstances where safe dysregulation adds to illness movement.
4. Angiogenesis regulation: It can affect the growth of new blood vessels or angiogenesis. It inhibits the synthesis of a protein, which plays a crucial role in angiogenesis. It limits excessive angiogenesis observed in certain diseases by inhibiting VEGF production.
These mechanisms collectively contribute to Halofuginone's ability to modulate collagen synthesis, attenuate fibrosis, regulate immune responses, and impact angiogenesis.
What Is Halofuginone Used for
It has shown potential therapeutic applications in various areas, and here are some areas where T has demonstrated activity:
1. Fibrotic issues: It has been widely read up for its enemy of fibrotic impacts. It shows a guarantee in hindering fibrosis movement in organs like the liver, lungs, kidneys, and skin. This makes it a possible contender for dealing with conditions like liver fibrosis, foundational sclerosis, and scleroderma.
2. Immune system and provocative infections: Its immunomodulatory properties have started an interest in the immune system and inflammatory problems. It has been inspected for rheumatoid joint torment, basic lupus erythematosus (SLE), and sclerosis. By tweaking safe responses and cytokine hailing, IT could help alleviate invulnerable framework interceded hurt.
3. Parasitic diseases: It has displayed antiparasitic effects against several pathogens. The patient's condition has been examined for rheumatoid arthritis, lupus erythematosus (SLE), and multiple sclerosis. By adjusting immune responses and cytokine signaling, there is a possibility that it could help alleviate the harm caused by the immune system.
Halofuginone Veterinary Use
Halofuginone is a pharmaceutical compound used in veterinary medicine to treat and prevent certain animal diseases. It is used mainly to control coccidiosis, a parasitic infection affecting various species' digestive tracts, such as poultry and livestock.
Coccidiosis can cause severe diarrhea, weight loss, and even death in infected animals. It works by inhibiting the development and spread of coccidia parasites, helping to control and reduce the severity of the infection.
Factory Environment
Certificates
Packaging
Logistics
In addition to guaranteeing product quality, the other most vital thing is clients can receive the goods smoothly. So, Xi’an Sonwu supplies all kinds of couriers according to different needs.
Company's Profile
Xi'an Sonwu Biotech Co . Itd is a professional Chinese manufacturer and products supplier. It was founded in 2012 in the Hi-Tech industrial Zone of Xi’an city, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plant extract, APl, and other ingredients of health care products. Our company supplies five raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. We sincerely believe that the premise of excellent cooperation is the best services and good quality. So, welcome your inquiry.
If you want to know the Halofuginone Powder, please don't hesitate to contact us online via:
E-mail:sales@sonwu.com
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