Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of clomiphene citrate powder in China. We warmly welcome yuo to wholesale bulk clomiphene citrate powder for sale here from our factory. Quality products and reasonable price are available.
What Does Clomiphene Mean
Clomiphene citrate powder, also known as clomifene, belongs to a kind of anti-hormonal drug. It is primarily used as a drug to cure infertility in women who do not ovulate, including women with polycystic ovary syndrome. This drug has both weak agonistic and antagonistic solid effects on estrogen, which can stimulate ovulation. Clinically, clomiphene is mainly used to treat anovulatory female infertility, and it is suitable for patients with a certain level of estrogen in the body. It can also treat corpus luteum insufficiency and ovarian test function. In addition, used to detect the abnormal part of the male hypothalamus-pituitary-gonadal axis and treat male infertility due to too few sperm. In short, the drug is a synthetic non-steroidal preparation with a chemical structure similar to diethylstilbestrol. It is a drug with a strong anti-estrogen effect and a weak estrogen effect. Belongs to the category of "Ovulation Inducing Agents" in the World Health Organization's Essential Medicines List. Its advent ushered in the era of assisted reproductive technology. If you want raw clomiphene citrate, Xi'an Sonwu must be the best choice.
Certificate Of Analysis
Item | Specification | Results |
Appearance | White Powder | Complies |
Specification | 99% min | 99.32% |
Mesh Size | 100 % pass 80 mesh | Complies |
Ash | ≤ 5.0% | 3.43% |
Loss on Drying | ≤ 5.0% | 3.57% |
Melting point | 116.5-118℃ | Complies |
Chemical Analysis | ||
Heavy Metal | ≤ 10.0 mg/kg | Complies |
Pb | ≤ 2.0 mg/kg | Complies |
As | ≤ 1.0 mg/kg | Complies |
Microbiological Analysis | ||
Residue of Pesticide | Negative | Negative |
Total Plate Count | ≤ 1000cfu/g | Complies |
Yeast&Mold | ≤ 100cfu/g | Complies |
E.coil | Negative | Negative |
Salmonella | Negative | Negative |
Where To Buy Clomiphene Citrate
Xi'an Sonwu Biotech Co. ltd. is a business with more than ten years of trade experience. It cooperates with countries in the Americas, Europe, Asia, and Oceania worldwide. Xi'an Sonwu has always kept an eye on product quality first. Satisfying every customer will and meeting every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls the selection of raw materials and produces high-quality products, such as manufacturing, testing, and selling. In addition, Xi'an Sonwu strives to do an excellent job in every detail and pursues to allow customers to obtain cost-effective products. Based on quality, sales, and after-sales service, customers have given good feedback on the products. So if you need clomiphene, don't hesitate to contact Xi'an Sonwu.
Xi'an Sonwu not only ultimately ensures product quality but also supplies the sample. Please check the quantity.
Form | Sample Amount | MOQ |
Powder | 50g | 100g |
Customers' Good Comment
How Does Clomiphene Work To Stimulate Ovulation
Clomiphene is a hormone drug, but its pharmacological mechanism is still unclear. It may work in a similar way to estrogen. It binds to estrogen receptors in the hypothalamus, competing with estrogen for these receptors, reducing their effects. This binding promotes the stimulation and secretion of GnRH to induce ovulation and may also act on the ovary to increase the follicular response to gonadotropins.
This product has dual effects of weak excitability and strong antagonism on estrogen. It acts on the hypothalamus and estrogen competition receptors through a small dose of drugs, relieves the feedback effect of estrogen, stimulates the release of endogenous GnRH, and promotes the release of the pituitary. Antagonism can preferentially interfere with the adverse effects of endogenous estrogen by competitively occupying hypothalamic estrogen receptors and instead promote the excretion of follicle-stimulating hormone and luteinizing hormone, thereby stimulating follicle growth. As follicles mature, estrogen release increases, stimulating preovulatory gonadotropin release to peak through positive feedback. When clomiphene is inhibited, GnRH decreases, causing estradiol to increase to 2 or 3 times the average amount. The increase in estradiol stimulates an LH surge, which triggers ovulation.
What Are The Benefits Of Clomiphene Citrate
According to relevant data reports, the success rate of clomiphene ovulation induction has reached nearly 80%. This data is a big surprise for female infertility patients, but the only regret is the low pregnancy rate. According to clinical practice, eat The chance of pregnancy with clomiphene is only about 20%, which is why some patients are successfully stimulated with clomiphene but not pregnant.
Clomiphene citrate powder uses clinically to detect male hypothalamus-pituitary-gonad axis dysfunction. The drug considerably affects treating male infertility due to too few sperm, so men can also take clomiphene.
Anovulatory female infertility;
Women with insufficient corpus luteum function;
Test a woman's ovarian function;
Treatment of male infertility due to too few sperm;
Detection of dysfunction of the hypothalamic-pituitary-gonadal axis in males.
What Are The Side Effects Of Clomiphene
1. The more common adverse reactions include swelling, stomach pain, pelvic or lower abdominal pain, ovarian enlargement or cyst formation or ovarian fibroid enlargement, and apparent ovarian growth, usually occurring a few days after stopping the drug.
2. Less common ones are: blurred vision, double vision, flashing light in front of the eyes, eyes sensitive to light, vision loss, and yellowing skin and sclera.
3. Attention should be paid when the following reactions persist: hot flashes, breast discomfort, constipation or diarrhea, dizziness or dizziness, headache, increased menstrual flow or irregular bleeding, appetite and weight gain, hair loss, mental depression, mental Tension, restlessness, insomnia, fatigue, nausea and vomiting, skin rash, allergic dermatitis, wheal, frequent urination, etc., may also cause weight loss. There are very few reports of breast cancer and testicular cancer abroad.
Clomifene Warnings
Unexplained irregular vaginal bleeding, uterine fibroids, ovarian cysts, liver function damage, mental depression, thrombophlebitis, etc., are contraindicated.
1. Animal experiments have teratogenic effects and fetal toxicity. During the medication period, measure basal body temperature daily to monitor patients' ovulation and conception, and the drug should be stopped once conception occurs. If pregnant women take medicine, there may also be a 5% chance of causing fetal malformations.
2. Polycystic ovary syndrome should be used with caution.
3. Carry out the following determinations as needed during the medication period:
1) Ovulation-stimulating hormone and luteinizing hormone;
2) For long-term drug users, measure the content of 24-dehydrocholesterol in plasma to determine whether the drug affects cholesterol synthesis.
3) Corticosteroid transfer protein content in plasma.
4) Serum thyroxine content.
5) Sex hormone binding globulin content.
6) Sodium sulfobromophthalein liver function test.
7) Thyroxine-binding globulin content (possibly increased).
4. During the medication should pay attention to checking:
Measure basal body temperature every day, and measure estrogen and serum progesterone levels when necessary; Liver function must be tested, and must be performed fundus and slit lamp examinations for those who have been treated for more than one year; If visual disturbance occurs during the medication, the drug should be stopped immediately, and should carry out the appropriate checks.
Clomiphene Use
The usual clomiphene dosage is 50mg daily, and five days is a course of treatment. If you do not ovulate after treatment, you need to increase the dose to 100mg and take another five days. If you still do not ovulate, you must increase the amount to 150mg. On the 5th, it is possible to ovulate.
However, women with menstruation and women without menstruation use clomiphene differently. Women with menstruation take clomiphene on the fifth day of the menstrual cycle, 50mg daily for five consecutive days. Women without menstruation can take clomiphene at any time, take 50mg a day, stop taking the medicine for five straight days, and usually ovulate after taking the medication for seven days.
Factory
1. From the view of product quality, Xi'an Sonwu has a factory to manufacture and test every batch of products. Xi'an Sonwu has a strict elimination measures department with professional equipment to supply data support for each product. Under the precise rules of Xi'an Sonwu, researchers continue to research and develop the products to ensure they produce products with higher specifications to meet customer needs.
2. Regarding service, Xi'an Sonwu has professional manufacturing personnel to select raw materials and produce products, advanced testing equipment, and skilled testing personnel to test products. Personnel with foreign sales experience to sell products and Xi'an Sonwu have unique lines for transportation in different countries and pursue to meet the requirements of every customer.
Certificate
Package
Logistics
Xi'an Sonwu, besides ensuring product quality, the most crucial thing is assisting customers in receiving the packets safely. Therefore, Xi'an Sonwu can supply all couriers according to different needs.
FAQ
If you want to know the clomiphene citrate powder price or have any problems asking Xi'an Sonwu, feel free to contact Xi'an Sonwu.
Email: sales@sonwu.com
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