Climbazole Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of climbazole powder in China. We warmly welcome yuo to wholesale bulk climbazole powder for sale here from our factory. Quality products and reasonable price are available.

What Is Climbazole Made Of
Climbazole powder, also known as climbazol, has the chemical name 1-(4-chlorophenoxy)-1-(1H-imidazole-1-yl)-3,3-dimethyl-2-butanone chloromethyl ketone, which is a synthetic chemical component. It is made by reacting chloromethyl ketone, imidazole, and toluene as raw materials and then undergoing processes such as crystallization, filtration, decolorization, and drying. It inhibits the manufacture of ergosterol, a crucial component of fungal cell membranes, which is how it kills fungi and possesses good antifungal qualities. It can kill ovoid spores and pityriasis tinea, inhibiting and eliminating dandruff and relieving itching. Due to its stable nature and poor solubility in water, it will not irritate the scalp and can also inhibit Candida albicans, which cause oral gingivitis and periodontitis. Therefore, it is an essential functional additive for daily chemical products and can be widely used in shampoo, conditioner, shower gel, soap, toothpaste, mouthwash, etc. Climbazole can also be used to make medications for eczema and to treat fungal infections of the skin. As you can see, it has good efficacy and safety, so if you need raw 99 powder climbazol, Xi'an sonwu can provide it.

Certificate Of Analysis

Climbazole Buy Online
Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. Xi'an Sonwu has established solid and reliable partnerships with countries in America, Asia, Europe, and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to meet their needs fully.
High-quality products are Xi'an Sonwu's top priority, and the company's dedication to perfection is seen in all aspects of its operations, including the selection of raw materials, manufacturing processes, sample testing, and staff professionalism. By meticulously managing every detail, Xi'an Sonwu can minimize costs without compromising quality, ensuring customers receive products of exceptional value.
Xi'an Sonwu is proud of the positive feedback it has received from customers, who have consistently recognized the quality of the products. To further prove product confidence, Xi'an Sonwu will provide samples for you to test.

Customers' Good Comment

What Is Climbazole Used For
1. Treat dandruff
One of the leading causes of dandruff is the overgrowth of Malassezia spp. and some other yeasts, such as Bacillus sebaceous, etc., which grow excessively on the scalp, causing dandruff and cause itching and inflammation of the scalp. By successfully blocking the fungus's growth, climbazol can lessen dandruff generation, support preserving the scalp's natural environment, and shield against fungal-related scalp issues.

2. Treat seborrheic dermatitis
Chronic inflammatory skin illness, known as seborrheic dermatitis, is frequently accompanied by erythema and scaling, which encourages the growth of Malassezia and exacerbates inflammation. By inhibiting fungal growth, the inflammatory response is reduced. Regularly using it products can effectively reduce the symptoms of redness, itching, and scaling of the scalp and skin.

3. Treating other fungal skin infections
In addition to seborrheic dermatitis and dandruff, it treats other fungal skin infections, such as Tinea corporis, Tinea pedis, and Tinea manuum. It can effectively inhibit the growth of various fungi, including but not limited to Candida albicans, thereby reducing the number and reproduction of fungi. For these fungal infections, it can reduce inflammation, itching, and other discomfort at the infected site, helping to restore skin health.

Note：
Tinea corporis is usually caused by Candida albicans (such as Trichophyton and Microsporum) and Epidermophyton floccosum. It usually presents as a round or irregular red spot on the skin with a well-defined border and a
gradual healing center. There may be slight scaling or bumps around the lesions.

Tinea pedis mainly affects the skin of the feet, especially between the toes. It is caused by Candida albicans (such as Trichophyton rubrum and Trichophyton mentagrophytes), which are often found in moist, warm environments such as public bathrooms, locker rooms, and swimming pools. The most common symptoms include moist, red, flaky, and itchy skin between the toes. The lesions may spread to soles, heels, and other feet.

Tinea manuum is a disease that mainly affects the skin of the hands. It is caused by Candida albicans (such as Trichophyton spp.), which are often found in soil, animals, human skin, and other surfaces. The most common symptoms include swelling, redness, peeling, and itching of the skin on the hands. Sometimes, symptoms also include the development of blisters or herpes.

How Does Climbazole Work
Climbazole powder's mechanism of action mainly involves its mechanism as an antifungal agent. Its main target is lanosterol 14α-demethylase in fungal cells. This critical enzyme in the ergosterol synthesis pathway converts lanosterol to ergosterol. By inhibiting the activity of 14α-demethylase, the synthesis of ergosterol is blocked. Ergosterol is one of the essential components of fungal cell membranes. Its deficiency leads to structural abnormalities of fungal cell membranes, and essential substances inside the cells (such as ions and small molecules) can be extravasated, affecting the function and integrity of the cell membrane. Climbazol may also inhibit the activity of some key enzymes in the fungus, especially enzymes involved in lipid metabolism and cell wall synthesis. These inhibitory effects affect the survival and reproduction of fungi. If ergosterol synthesis is hindered, it will lead to abnormalities in the structure and function of fungal cell membranes, thereby affecting the survival of fungi. Damage to the cell membrane causes fungal cells to lose their typical internal cell environment, and this imbalance hastens the fungal cells' inevitable demise.

Climbazole Side Effects
Skin Irritation
Some persons, especially those with sensitive skin or those allergic to it, may experience moderate skin irritation, such as redness, itching, or a burning feeling.

Allergic Reactions
Although uncommon, allergic reactions to climbazole can occur. Symptoms may include rash, hives, swelling, or difficulty breathing.

Eye Irritation
Direct contact with it-containing products can irritate the eyes, causing redness, tearing, or discomfort.

Dryness or Flaking
Prolonged or excessive use of it products, especially those formulated for scalp treatment, may lead to dryness or flaking of the scalp or skin.

Discoloration of Hair
It may cause temporary hair discoloration in some cases, mainly if used in higher concentrations or left on the hair for extended periods.

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture, and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

Certificates

Packaging

Logistics

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ
What precautions should be taken when using this product?
Recommended dosage: 0.4%-1%
Applied products: shampoo, shower gel, soap, toothpaste, mouthwash
Raw material advantages
1. Broad-spectrum bactericidal and good anti-dandruff effect
2. Soluble in surfactants, easy to use, no worries about stratification.
3. Stable to metal ions, no yellowing or discoloration.
4. Stable structure, no irritation to the scalp.
It can be an ingredient in lotions, shampoos, lotions or ointments. The specific usage and product type should be selected according to the particular condition and doctor's advice.

If you want to know the price of 99 powder climbazol, you can contact Xi'an Sonwu. Click the email, and then you get high-quality climbazole powder.
Email: sales@sonwu.com

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