99% Dasatinib Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 99% dasatinib powder in China. We warmly welcome yuo to wholesale bulk 99% dasatinib powder for sale here from our factory. Quality products and reasonable price are available.

What Is Dasatinib

99% dasatinib powder is a kind of orally available small-molecule multikinase inhibitor. Not only does it effectively restrict BCR-ABL and SRC-family kinases (SRC, LCK, YES, FYN), but also inhibit C-KIT, PDGFR- αandβ , and ephrin receptor kinase. This medicine has been proved that it is active against clinically relevant mutation, including Imatinib treatment. It is a kind of inhibitor of various tyrosine kinase, including BCR-ABL kinase related to chronic granulocytic leukemia and other cancer. It mainly cures chronic, accelerated myeloid or lymphoblastic chronic myeloid leukemia in adults. Beyond that, it could ameliorate the symptom that is resistant to imatinib. This product is used to treat adult patients with Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) who are resistant to imatinib mesylate or who are intolerant to it in the chronic, accelerated and acute phases (acute myeloid and acute lymphocytic).

Because of its good effect and appliacations, there are more and more dasatinib manufacturers. As one of them, Xi'an Sonwu guarantees to supply top quality products at the competitive price. So if you are interested in it, feel free to contact Xi'an Sonwu.

Certificate of Analysis

Dasatinib Buy

Xi'an Sonwu Biotech Co. ltd. has rich experience in global trade and health industry. Insist on faith-based and quality first is our company’s principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce cost to the maximum extent, then our customers can get cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. ltd. when you need raw dasatinib.

Xi'an Sonwu completely makes sure product’s quality, so sample can be supplied. Here is the quantity.

Customers’ Good Comment

OEM Service

Xi'an Sonwu not only can supply high quality 99% dasatinib powder, but also supply different pacakaging.

So any customers could customize pacakaging they want. And items below can be supplied.

1. Customized label(paint film, matte film, optical mask)

2. Customized packaging(vacuum foil packaging, box, drum)

Which Adverse Effect Is The Most Common For Dasatinib

Dasatinib is a tyrosine kinase inhibitor that is used to treat various forms of serious illness, including chronic myeloid leukemia and acute lymphoblastic leukemia. While dasatinib is generally well-tolerated, there are some potential adverse effects associated with its use. One of the most common adverse effects is myelosuppression, which is a decrease in the production of blood cells. This can lead to anemia, neutropenia, and thrombocytopenia, which are conditions characterized by low levels of red blood cells, white blood cells, and platelets, respectively.

Myelosuppression is a common adverse effect of dasatinib because the drug inhibits the activity of tyrosine kinases, which are enzymes that play important roles in the regulation of cell growth and proliferation. By inhibiting these enzymes, dasatinib can interfere with the normal development and maturation of blood cells, leading to myelosuppression.

In addition to myelosuppression, dasatinib can also cause other adverse effects, including gastrointestinal disturbances, such as nausea, diarrhea, and vomiting. These symptoms are thought to occur because dasatinib can irritate the lining of the gastrointestinal tract, leading to inflammation and discomfort.

Other common adverse effects of dasatinib include fatigue, headache, and fluid retention. Fluid retention can cause swelling in the hands and feet, as well as weight gain. In rare cases, dasatinib can also cause serious adverse effects, such as pulmonary arterial hypertension, which is a condition characterized by high blood pressure in the arteries that supply the lungs. This condition can lead to shortness of breath, chest pain, and fatigue, and can be life-threatening if left untreated.

Dasatinib Mechanism Of Action

Dasatinib is a tyrosine kinase inhibitor that is used to treat various forms of serious illness, including chronic myeloid leukemia and acute lymphoblastic leukemia. The medicine works by inhibiting the activity of specific tyrosine kinases that are involved in the abnormal growth and proliferation of cancer cells.

Tyrosine kinases are enzymes that play important roles in the regulation of cell growth, differentiation, and survival. They are activated by binding to specific ligands, such as growth factors or cytokines, and then phosphorylate target proteins, leading to downstream signaling pathways that regulate cell function. In bad cells, tyrosine kinases become overactive, leading to uncontrolled cell growth and proliferation.

Dasatinib works by inhibiting the activity of multiple tyrosine kinases, including BCR-ABL, SRC family kinases, and c-KIT. BCR-ABL is a fusion protein that is produced by the Philadelphia chromosome translocation, which is found in the majority of patients with chronic myeloid leukemia. BCR-ABL has constitutively active tyrosine kinase activity, leading to the abnormal proliferation and survival of leukemic cells. Dasatinib binds to the ATP-binding site of BCR-ABL, preventing its tyrosine kinase activity and inhibiting downstream signaling pathways that promote cell growth and survival.

SRC family kinases are another group of tyrosine kinases that are involved in the regulation of cell growth, differentiation, and survival. They are overexpressed or activated in a variety of serious illness types, including breast and colon. Dasatinib inhibits the activity of SRC family kinases, preventing downstream signaling pathways that promote cell growth and survival.

c-KIT is a tyrosine kinase that is important for the development and differentiation of hematopoietic stem cells. It is overexpressed or mutated in a variety of cancers, including gastrointestinal stromal tumors, melanoma, and acute myeloid leukemia. Dasatinib inhibits the activity of c-KIT, preventing downstream signaling pathways that promote cell growth and survival.

In addition to its effects on tyrosine kinases, dasatinib can also affect other signaling pathways that are involved in the regulation of cell growth and survival. For example, the drug can inhibit the activity of the PI3K/AKT/mTOR pathway, which is frequently activated in bad cells and promotes cell growth and survival. Dasatinib can also activate the JNK pathway, leading to apoptosis or cell death in bad cells.

What Is The Drug Dasatinib Used For

Dasatinib is a medication that belongs to a type of drug known as tyrosine kinase inhibitors. It is used to treat chronic myeloid leukemia (CML), a type of bad disease that affects the white blood cells by blocking the abnormal proteins that cause the cancer cells to grow and divide.

Chronic myeloid leukemia is caused by a genetic mutation that results in the formation of an abnormal protein called BCR-ABL. This protein promotes the uncontrolled growth of white blood cells, which leads to the development of bad cells. Dasatinib works by blocking the activity of BCR-ABL, which slows down the growth and division of bad cells.

In addition to CML, dasatinib is also approved for the treatment of certain types of acute lymphoblastic leukemia (ALL) and gastrointestinal stromal tumors (GISTs). It has been shown to be effective in patients who have not responded well to other types of chemotherapy.

Factory Environment

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

Certifications

Packaging

Logistics Record

FAQ

1.How to contact Xi'an Sonwu Biotech Co., Ltd.?

You can contact by email, telephone number, social media.

2.How to make sure the quality of product?

We test each batch, so can supply COA for customers. Besides, our product pass the test: HPLC, UV, GC, TLC etc. And we also cooperate with the third parties, like, SGS.

3.How to pack and store?

Pack:Vacuum sealed foil packaging & Sealed export grade drum or pack according to customers’need.

Storage: keep it in a dry and cool place, and make it avoid strong light and heat.

If you want to buy 99% dasatinib powder, feel free to contact Xi'an Sonwu.

E-mail: sales@sonwu.com

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