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Bupropion Hcl Powder

Bupropion Hcl Powder

Appearance: White or off-white solid powder
Specification: 98%
CAS: 31677-93-7
Molecular Formula: C13H19Cl2NO
Molecular Weight: 276.2
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of bupropion hcl powder in China. We warmly welcome yuo to wholesale bulk bupropion hcl powder for sale here from our factory. Quality products and reasonable price are available.

 

Is Bupropion A Supplement
Bupropion Hcl powder is not a supplement. Instead, it is a drug that belongs to the aminoketone class of drugs. The main uses of bupropion are as an antidepressant for treating severe depression and as a smoking cessation aid to lessen withdrawal symptoms and cravings for nicotine. It can also be applied to the treatment of SAD or seasonal affective disorder. It's a dopamine and norepinephrine reuptake inhibitor. It has most of its reuptake-inhibitory and dopamine-activating properties. Patients taking long-term, high-dose bupropion can downregulate beta-adrenergic receptors. This drug is used for bipolar depression, late-onset depression, excessive sleepiness, cognitive retardation or pseudodementia, and those who are ineffective or intolerant to drugs such as serotonin. It can also be used for brokenness and longing, attention deficit disorder, quitting smoking, and withdrawal from stimulants. Bupropion raises dopamine and norepinephrine levels in the brain, which are linked to depression and withdrawal symptoms. The drug blocks nerve cells' normal reuptake of neurotransmitters and allows them to remain in the brain. The more dopamine and norepinephrine you have, the less anxious you will feel while also increasing your feelings of pleasure. When using bupropion as a smoking cessation medication, you may continue smoking during the first or second week after starting treatment. After this treatment period, the desire to smoke and withdrawal symptoms will decrease and eventually disappear altogether. If you are also interested in antidepressant products, please get in touch with Xi'an Songwu. Xi'an Sonwu can provide you with pure bupropion hydrochloride powder.

Bupropion Hcl structure

 

Certificate Of Analysis

Items

Specification

Results

Appearance

White or off-white solid powder

Complies

Identification

By IR

Complies

By HPLC

Complies

Solubility

Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water

Complies

Polymorphic Form

Polymorphic form 1

Complies

Melting Point

211ºC~216ºC

212.8~214.9

Water Content

≤ 0.50%

0.10%

Heavy Metals

≤ 20ppm

Complies

Residue on Ignition

≤ 0.20%

0.09%

Related Substance

Any single impurity: ≤0.10%

0.06%

Total Impurities: ≤1.00%

0.16%

Assay

(on the anhydrous basis)

98.0%~102.0%

99.94%

Particle Size

D90: ≤100µm

Complies

 

Buy Bupropion Online
Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. Xi'an Sonwu has established solid and reliable partnerships with countries in America, Asia, Europe, and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to meet their needs fully.
Xi'an Sonwu prioritizes high-quality products, and its commitment to excellence is evident in every aspect, including material selection, manufacturing techniques, sample testing, and the professionalism of its personnel. By meticulously managing every detail, Xi'an Sonwu can minimize costs without compromising quality, ensuring customers receive products of exceptional value.
Xi'an Sonwu is proud of the positive feedback it has received from customers, who have consistently recognized the quality of the products. To further prove product confidence, Xi'an Sonwu will provide bupropion hydrochloride powder samples for you to test.

Form

Sample Amount

The Minimum Of Quantity

Powder

1kg

1kg

 

Customers's Good Comment

-301

 

What Does Bupropion Do To The Brain
Bupropion Hcl powder is a new antidepressant. It mainly has antidepressant, anti-anxiety, and anti-obsessive-compulsive effects. It has no manic conversion effect, and it does not convert a patient's depressive symptoms into mania. Crazy symptoms. Therefore, if a patient with bipolar disorder has significant depression or even a tendency to repeatedly self-harm or commit suicide, the dose of bupropion can be gradually increased based on using a mood stabilizer. It is a drug that works through a different mechanism than most other antidepressants. It produces antidepressant effects primarily by inhibiting the reuptake of the neurotransmitters dopamine and norepinephrine. Unlike medications like SSRIs (selective serotonin reuptake inhibitors) and SNRIs (norepinephrine and serotonin reuptake inhibitors), bupropion hydrochloride rarely causes side effects such as decreased libido and weight gain. Research suggests that bupropion hydrochloride may show different advantages than other antidepressants in treating certain types of depression. For example, some studies have found that bupropion hydrochloride can improve specific symptoms (such as attention deficit and anxiety) more significantly in some patients.


1. Adult major depression
Major depressive disorder in adults is a severe psychological illness characterized by persistent low mood, loss of interest and joy, decreased self-esteem, and other symptoms that affect cognitive and physical functioning. Treating significant depression requires a comprehensive approach, including psychotherapy and medication. The choice of pharmacotherapy depends on the individual situation. Bupropion Hydrochloride may be used to treat major depressive disorder in adults, particularly those with anxiety or a desire to quit smoking.

Adult major depression


2. Assist in smoking cessation
Assisted smoking cessation is a vital step that can provide additional support and assistance in the smoking cessation process. Bupropion Hydrochloride is a commonly used smoking cessation aid that helps people quit smoking by reducing the symptoms of nicotine withdrawal. This medication is usually given as part of a comprehensive smoking cessation program.


3. Prevent seasonal depression
Seasonal depression (SAD) is a season-specific depressive disorder that typically occurs during winter when light exposure is reduced. Symptoms may include depressed mood, insomnia, changes in appetite, and lack of energy. Bupropion Hydrochloride is commonly used to treat seasonal affective disorder (SAD) in adults. The medication can help relieve the symptoms of SAD and improve mood by increasing levels of dopamine and norepinephrine in the brain. It can also be used for obsessive-compulsive disorder, phobias, social phobia, anxiety disorders, and bulimia/anorexia nervosa.

seasonal depression


What Are The Side Effects Of Bupropion
According to foreign clinical research results, the adverse reactions of bupropion are as follows:

The occurrence rate is more than 1%, and common symptoms include edema, frequent urination, dry mouth, headaches, nausea, vomiting, dizziness, and headaches.
In rare cases (occurrence rate 1%~0.1%), abnormal liver function, gastritis, migraine, tachycardia, delusions, hallucinations, changes in appetite and weight, etc., are observed.
It will be caused by rare cases (occurrence rate less than 0.1%) of ataxia, anemia, etc.

Side Effects Of Bupropion

Other adverse events observed in clinical studies with unclear relevance to bupropion include:
Systemic symptoms: Common symptoms include weakness, fever, and headache; occasionally, back pain, chills, inguinal hernia, pain, and light sensitivity; rare symptoms include fatigue and discomfort. Arthralgia, myalgia, fever with rash, and other delayed allergic reactions have also happened. These symptoms may mimic those of serum sickness.
Cardiovascular system: Occasionally, facial flushing, migraine, orthostatic hypotension, stroke, tachycardia, vasodilation, and rarely syncope. Cardiovascular dysfunction, complete atrioventricular block, and premature contractions may also happen. , hypotension, hypertension, myocardial infarction, phlebitis, and pulmonary embolism.
Digestive system: Common indigestion, bloating, and vomiting; occasionally abnormal liver function, nighttime teeth grinding, dysphagia; gastric reflux, gingivitis; glossitis, jaundice, and stomatitis; rare tongue edema. Colitis, esophagitis, gastrointestinal bleeding, gum bleeding, hepatitis, sialorrhea, intestinal perforation, liver impairment, pancreatitis, gastric ulcers, and stool abnormalities may also happen.
Endocrine system: Hyperglycemia, hypoglycemia, and abnormal antidiuretic hormone secretion syndrome may happen.
Hemolymphatic system: occasional ecchymosis. Anemia, leukocytosis, leukopenia, lymphadenopathy, pancytopenia, and thrombocytopenia may happen.
Metabolism and Nutrition: Occasionally, edema, weight gain, and peripheral edema may occur.
Musculoskeletal: Leg cramps may occasionally occur, arthritis, muscle stiffness/pyrexia/rhabdomyolysis, and muscle atrophy may also happen.
Nervous system: typical irritation, depression, and agitation. Anomalous coordination, central nervous system irritation symptoms, disorientation, reduced sexual desire, memory loss, personality loss, unstable emotions, aggression, hyperkinesia, hypertonia, hypoesthesia, unusual feelings, suicidal thoughts, and vertigo are occasionally observed. Amnesia, ataxia, derealization, and hypomania are uncommon. There may also be extrapyramidal symptoms, loss of motor function, aphasia, coma, confusion, delusions, dysphonia, dystonia, intoxication, hypokinesia, increased libido, mania, neuralgia, and electrocardiographic abnormalities: tardive dyskinesia, neurosis, and paranoid responses.
Cutaneous System: Sweating is common. Acne and dry skin are occasionally seen. Rare maculopapular rash. Alopecia, angioedema, exfoliative dermatitis, and hirsutism may also happen.
Special senses: Amblyopia is widespread. Dry eye syndrome and problems related to accommodation rarely happen. There may also be signs of mydriasis, diplopia, and deafness.

 

Factory
1. Xi'an Sonwu Biotech Co., Ltd has a factory to produce, manufacture, and store the products, so it has adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

302

 

Certificate

303

 

Package

304

 

Logistics

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Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics


FAQ
When taking the drug, start with a small dose; the initial dosage is 75 mg once; after taking it for at least three days, according to the clinical efficacy and tolerance, the dosage can be gradually increased to 75 mg once; later, it can be continued to gradually increase to the usual daily dose of 300 mg as appropriate.
During the dosage increase process, the dosage increase within three days shall not exceed 100 mg daily. As an antidepressant, this product usually needs to be taken for four weeks to show apparent effects. Suppose there is still no noticeable effect after several weeks of continuous use. In that case, consider gradually increasing it to the maximum daily dose of 450 mg, but the total amount should be at most 150 mg each time.

 

If you want to know the bupropion hydrochloride powder manufacturer, you can contact Xi'an Sonwu. Click the email, and then you get high-quality bupropion Hcl powder.
Email: sales@sonwu.com

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