Atropine Sulfate Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of atropine sulfate powder in China. We warmly welcome yuo to wholesale bulk atropine sulfate powder for sale here from our factory. Quality products and reasonable price are available.

What Class Of Drug Is Atropine
Atropine sulfate powder is an anticholinergic drug, that is, a drug that blocks choline receptors so that the transmitter acetylcholine cannot bind to the receptors and presents the opposite effect to cholinergic drugs, such as commonly used antispasmodic and pain-relieving drugs. It can attach to M-choline receptors and antagonize the muscarinic effects of acetylcholine and other cholinergic drugs. Atropine sulfate is mainly used to relieve the spasm of smooth muscle, inhibit glandular secretion, alleviate the inhibition of the vagus nerve on the heart, make the heart beat faster, dilate the pupil, increase intraocular pressure, and excite the respiratory center.
In daily life, the application of atropine sulfate is mainly in raw material and liquid form, but both are based on high-quality powder. So if you want pure atropine sulfate, you can search Xi'an Sonwu.

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Where To Buy Atropine Sulfate
Xi'an Sonwu Biotech Co. ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. Xi'an Sonwu strictly controls product quality, which means selection starts from raw materials. Besides, Xi'an Sonwu handles every detail and reduces the cost to the maximum extent so that customers can get a cost-effective product. Based on these, customers have given much good feedback to products. So look for Xi'an Sonwu Biotech Co. ltd. when buying atropine sulfate.
Xi'an Sonwu not only ensures the product's quality but also offers samples. Please check the quantity.

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What Does Atropine Sulfate Do
1. Used for various heart angina
Common symptoms include joint stomach pain, intestinal colic, renal colic, and bladder irritation. You can use histamine H2 receptor blockers and weakly alkaline antacids for peptic ulcers.

2. For administration before anesthesia
Reduce bronchial mucus secretion during anesthesia to prevent respiratory obstruction and aspiration pneumonia, and remove the inhibition of morphine on the respiration. Relieving the excitability of the vagus nerve can prevent laryngeal spasms caused by sodium sulfate.

3. For ophthalmology
To treat iridocyclitis, dilate the pupils, relax the ciliary muscles, achieve the purpose of anti-inflammatory and pain relief and prevent iris and crystal adhesion.
It is used to open pupils before children's optometry. In recent years, short-term mydriatics such as cyclopentyl ether and tropicamide have been used to avoid unpleasant sensations such as photophobia and blurred vision brought to patients after atropine optometry.

4. Anti-shock
It can use for fulminant meningitis, toxic dysentery, and septic shock caused by toxic pneumonia. To supplement the blood volume, a higher dose of atropine sulfate can relieve arteriolar spasms, improve microcirculation, increase blood pressure, and improve symptoms.

5. Rescue organophosphate poisoning
It can quickly relieve the symptoms of M-choline and central nervous system symptoms of organophosphate poisoning. Still, atropine sulfate cannot control the heartbeat, myotonia, and other nicotinic substances, which is why it cannot eliminate the poisoning. Therefore, the cholinesterase revitalizer should be applied simultaneously when the poisoning is moderate or above.

Atropine Sulfate Side Effects
1. Dry mouth, palpitations, dilated pupils, blurred vision, dry skin, elevated body temperature, and urinary retention are standard.

2. If the dose is too large, there will be symptoms of central nervous system excitement, such as irritability, delirium, and convulsions. Excessive excitement turns into inhibition, difficulty in breathing, and death.
The rescue of atropine poisoning is mainly for symptomatic treatment, such as sedation with a small dose of phenobarbital, artificial respiration, and oxygen. When necessary, you can use neostigmine for peripheral symptoms.
 

What Is The Mechanism Of Atropine Action
Generally speaking, what we call atropine refers to atropine sulfate, which is a racemic scopolamine extracted from belladonna, datura, or scopolamine in the family Solanaceae. The difference between them is that atropine is an alkaloid that is easily soluble in organic solvents, and atropine sulfate is a strong acid and weak base salt that is easily soluble in water. However, whether it is atropine or atropine sulfate, their main ingredient is atropine, the usage and usage are the same, and the mechanism of action is also similar.
The mechanism of action of atropine is the competitive antagonism of M-choline receptors. It can compete with acetylcholine for the acetylcholine M-receptor of the postsynaptic membrane of the postganglionic parasympathetic fibers, thereby antagonizing the muscarinic symptoms and central nervous system symptoms caused by excessive acetylcholine stimulation of the postsynaptic membrane. After it binds to M choline receptors, it blocks the binding of ACh or cholinergic receptor agonists to the receptors, thereby antagonizing their agonistic effects. Atropine has high selectivity to M receptors, but it can also block the N receptors of ganglia in large doses. Atropine has low selectivity to various M receptor subtypes and has blocking effects on M1, M2, and M3 receptors.

Atropine sulfate powder inhibits smooth muscle activity and glands innervated by postganglionic cholinergic receptors. Depending on the dose of the product, it can stimulate or inhibit the central nervous system. Detoxification antagonizes the effect of cholinesterase inhibitors at the M-choline receptor site, such as increasing the secretion of mucous glands and salivary glands in the trachea and bronchi, contraction of bronchial smooth muscle, and hyperactivity of vegetative ganglia after stimulation. In addition, atropine can excite or inhibit the central nervous system in a dose-dependent manner. It has a more substantial and longer-lasting effect on the heart, intestine, and bronchial smooth muscle than other belladonna alkaloids.

Atropine Dose
1. The usual dosage is 0.5mg~3mg per day and 0.3mg~0.5mg/per time. Young children have poor tolerance. 0.2 mg ~ 10mg can be poisoned to death. Children 0.01mg/kg each time.
2. Administer 0.5 mg before anesthesia.
3. Organophosphate poisoning, mild poisoning: 0.5mg-1.0mg/time, 2-3 times/day, moderate poisoning: 1mg-2mg/time. Decrease the dose as appropriate after the condition improves. Severe poisoning and unconsciousness should be applied early, in sufficient quantities, and continuously. Generally, 2mg/time, until symptoms such as flushing of the face, dilated pupils, decreased glandular secretion, dry mouth, and mild restlessness appears, it can reduce to 1mg to maintain it. If the symptoms of poisoning recur, the injection can be repeated according to the above dose, and the total amount in 24 hours can be up to 50 mg if necessary. A complete cure also requires the combined application of cholinesterase revitalizers.
4. Anti-shock, supplementing blood volume, generally 0.02mg ~ 0.05mg/kg, until flushing, warm limbs, moderately dilated pupils, systolic blood pressure above 10.6kPa (80 mmHg), gradually Reduced to non-use.
5. For A-Story syndrome, 1 mg to 2 mg each time until the attack stops and there is no recurrence within 24 hours.
6. For status asthmaticus, the dose is 1 mg to 3 mg.

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

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Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

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If you want to know atropine sulfate price, you can contact Xi'an Sonwu. Click the email then you get high-quality atropine sulfate powder.
Email: sales@sonwu.com

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