99 Phenacetin Powder

What Is The Classification Of Phenacetin

99 Phenacetin Powder is a white crystalline powder previously used to treat conditions such as headaches, arthritis, and muscle aches. However, due to its association with kidney damage and cancer, it has been withdrawn from the market in many countries and is no longer recommended for medical use.

This product is not classified as a nonsteroidal anti-inflammatory drug (NSAID). While NSAIDs like ibuprofen and aspirin also provide pain relief and reduce inflammation, Acetophenetidin's mechanism of action is different. It is classified as a non-opioid analgesic and antipyretic drug. It belongs to the class of drugs known as para-aminophenol derivatives. Seeking advice from a healthcare professional regarding safe and efficient pain management measures is imperative.

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Where To Buy Phenacetin

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you need Phenacetin supplement.

Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.

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What Is Phenacetin Used For

This product has an interesting history and a notable profile in the landscape of pharmaceuticals. It was primarily used to relieve pain and reduce fever. Initially hailed as a medical breakthrough, it became popularity for its effectiveness in treating various conditions, from headaches to post-surgical pain. Research institutions worldwide studied its applications extensively, making it a staple in over-the-counter medications for decades.

The mechanism of action of it is primarily centered around its analgesic and antipyretic properties. It works by inhibiting the cyclooxygenase, which plays a key role in synthesizing prostaglandins. Prostaglandins are lipid compounds that perform several functions in the body, including mediating inflammation and pain. By suppressing the production of these compounds, It effectively reduces pain and inflammation. Additionally, it is metabolized in the body to produce paracetamol (acetaminophen), which further contributes to its analgesic effects. The drug's antipyretic action involves acting on the hypothalamus, the area of the brain responsible for controlling body temperature. By influencing this area, Acetophenetidin helps reduce fever, providing relief from symptoms associated with various infections and illnesses.

What Is The Pathway Of Phenacetin

Acetophenetidin is primarily metabolized in the body through two main pathways:

1. O-deethylation: This pathway involves the removal of the ethoxy group (C2H5O) from Acetophenetidin, resulting in the formation of paracetamol (acetaminophen) and ethanol as metabolites.

2. N-hydroxylation: It can also undergo N-hydroxylation to form a reactive metabolite known as N-hydroxy-phenacetin. This metabolite can further be converted to a highly toxic and carcinogenic compound named N-hydroxy-phenacetin quinone imine, which can lead to DNA damage and cellular toxicity.

Additionally, this products can be further metabolized through various pathways involving conjugation with sulfate and glucuronic acid and oxidation reactions. Overall, the metabolism of it can lead to the formation of both non-toxic metabolites like paracetamol and toxic metabolites that can induce cellular damage and carcinogenesis.

What Is The Difference Between Phenacetin And Paracetamol

They are related compounds that have similarities but also important differences:

1. Chemical Structure:

Phenacetin chemically known as acetophenetidin, it has the molecular formula C₁₀H₁₃NO₂. Paracetamol (Acetaminophen), also known as acetaminophen, has the molecular formula C₈H₉NO₂.

2. Medical Use:

99 Phenacetin Powder was historically used as an analgesic (pain reliever) and antipyretic (fever reducer). Paracetamol (Acetaminophen) is a widely used over-the-counter medication for pain relief and fever reduction. It is considered safer than Acetophenetidin and is commonly used for various types of pain.

3. Metabolism:

Acetophenetidin is metabolized in the body to form paracetamol (acetaminophen) along with other metabolites. Paracetamol (acetaminophen) is primarily metabolized in the liver into inactive compounds that are eliminated from the body.

4. Safety Profile:

Acetophenetidin has been associated with kidney damage, cancer risk, and the formation of toxic metabolites, leading to its ban in many countries. In general, paracetamol is regarded as safe when used as prescribed, although overdose can cause liver damage.

5. Current Availability:

Acetophenetidin is no longer recommended for use in pharmaceutical products due to safety concerns. Paracetamol (acetaminophen) is widely available over-the-counter for pain relief and fever reduction.

In summary, while both of them are related compounds with some shared properties, the two substances have different safety profiles and approved uses. It's important to follow medical advice and use medications as directed by healthcare professionals. If you have any questions about pain relief medications, it's best to consult with a healthcare provider before using phenacetin supplement. If you have any further questions or need more information, feel free to ask.

Why Was Phenacetin Banned

Many nations have prohibited or limited Acetophenetidin because of safety concerns and negative health effects linked to its use. Here are some reasons why this product was banned:

1. Kidney Damage: It's use has been linked to kidney damage, particularly a condition known as analgesic nephropathy. Prolonged use of it has been associated with the development of kidney disease, including renal papillary necrosis, a severe condition that can lead to kidney failure.

2. Cancer Risk: Renal cell carcinoma and urinary bladder transitional cell carcinoma are two malignancies for which Acetophenetidin has been associated with a higher risk.

3. Toxic Metabolites: The metabolic breakdown of Acetophenetidin in the body can lead to the formation of toxic metabolites, such as p-aminophenol and reactive metabolites, which can cause oxidative stress, DNA damage, and cellular toxicity.

4. Safer Alternatives: Safer alternatives for pain relief and fever reduction, such as acetaminophen (paracetamol), have been developed and are widely available. These alternatives provide effective pain relief with a lower risk of adverse effects compared to Acetophenetidin.

Due to these safety concerns and the availability of safer alternatives, many regulatory authorities have restricted or banned the use of Acetophenetidin in pharmaceutical products. It is important to follow regulations and recommendations regarding the use of medications to ensure safety and efficacy.

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

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Logistics Update

In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

Company's Profile

Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry if you want Phenacetin supplement.

And if you want to know the 99 Phenacetin Powder price, please contact XI'an Sonwu.

Email: sales@sonwu.com

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