7 Hydroxy 4 Methylcoumarin Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 7 hydroxy 4 methylcoumarin powder in China. We warmly welcome yuo to wholesale bulk 7 hydroxy 4 methylcoumarin powder for sale here from our factory. Quality products and reasonable price are available.

What Is 7-Hydroxy-4-Methylcoumarin Used For

7 Hydroxy 4 methylcoumarin powder, or 4 MU powder (4-methylumbelliferone), is a derivative of coumarin, a naturally occurring aromatic organic compound. It is an essential intermediate for synthetic fragrances, medicines, pesticides, and dyes and can be used as fluorescent and acid-base indicators. It is widely used as a fluorescent dye, insecticide intermediate, and biliary spasmolytic. 7-Hydroxy-4-methylcoumarin is a white or off-white crystalline powder, odorless and tasteless. It is slightly soluble in methanol, ethanol, and propanol, insoluble in water, and easily soluble in sodium hydroxide solution; the pH of the saturated aqueous solution is 6-7. It shows light purple fluorescence when dissolved in alcohol, blue fluorescence when added to sodium hydroxide test solution, and disappears when a small amount of dilute hydrochloric acid is added. It shows yellow-green solid fluorescence when irradiated under ultraviolet light. 7-Hydroxy-4-methylcoumarin is a new type of choleretic drug. It relaxes the sphincter of the bile duct opening and has a solid antispasmodic and analgesic effect. It can also gently and continuously promote bile secretion, strengthen gallbladder contraction, and have antibacterial effects. It has a significant choleretic impact, is conducive to the discharge of stones, and has a particular stone discharge effect on common bile duct stones. Some patients with elevated alanine aminotransferase returned to normal after the drug had eliminated inflammation. 7-Hydroxy-4-methylcoumarin is widely used in scientific research due to its fluorescent properties and biological activity. If you need, Xi'an Sonwu can supply 7 Hydroxy 4 methylcoumarin. Xi'an Sonwu is looking forward to hearing from you.

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Where To Buy 7 Hydroxy 4 Methylcoumarin

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce costs to the maximum so our customers can get cost-effective products. Based on these, customers have given a lot of good feedback about our products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying 7 Hydroxy 4 Methylcoumarin.

Xi'an Sonwu ensures product quality and can provide samples. Here is the quantity.

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7 Hydroxy 4 Methylcoumarin Uses

7-Hydroxy-4-methylcoumarin, or 4-Methylumbelliferone (4-MU), is a versatile compound with various uses across different fields. Here are some of its primary applications:

A. Biological and Medical Research:

1. Hyaluronan Inhibition:

Cancer Research: 4-MU is a well-known inhibitor of hyaluronan synthesis, which is significant in cancer biology. The extracellular matrix component hyaluronan is linked to tumor growth and metastasis when it is produced in excess. By inhibiting hyaluronan, 4-MU can potentially reduce tumor progression and spread.

Inflammatory Diseases: Due to its role in reducing hyaluronan, 4-MU has also been studied for its anti-inflammatory effects. In models of inflammatory disorders such rheumatoid arthritis and atherosclerosis, it has been demonstrated to reduce symptoms.

2. Pharmacological Studies:

Drug Development: 4-MU is used to develop and test new drugs. Its effects on hyaluronan make it a candidate for therapeutic interventions in various conditions involving excessive extracellular matrix production.

B. Biochemical Assays:

1. Enzyme Activity Measurement:

Fluorometric Assays: 4-MU is widely used in assays to measure the activity of enzymes such as β-glucuronidase. In these assays, non-fluorescent substrates like 4-methylumbelliferyl-β-D-glucuronide are cleaved by the enzyme to release the fluorescent 4-MU, allowing quantification of enzyme activity through fluorescence measurement.

2. Analytical Chemistry:

Fluorescent Marker: Due to its intense blue fluorescence under UV light, 4-MU is utilized as a fluorescent marker in various analytical techniques. This property is exploited in chromatography, spectroscopy, and other methods to detect and measure specific compounds or reactions.

C. Industrial Applications:

1. Cosmetics and Personal Care Products:

Skin Whitening: 4-MU has been explored for its skin-whitening properties, as it can inhibit the synthesis of hyaluronan, which is involved in skin hydration and elasticity. Regulating hyaluronan levels may contribute to a more even skin tone.

2. Food Industry:

Fluorescent Indicator: In food safety and quality control, 4-MU can serve as a fluorescent indicator for detecting certain contaminants or the activity of specific enzymes that may affect food quality.

Laboratory Reagent:

Research Tool: 4-MU is commonly used as a standard reagent in biochemical and molecular biology laboratories for various experiments involving enzyme kinetics, fluorescence imaging, and cellular studies.

Safety and Handling:

While generally considered low toxicity, proper safety measures should be observed when handling 7-Hydroxy-4-methylcoumarin. This entails working in a well-ventilated space to prevent breathing in dust or fumes and wearing personal protection equipment (PPE) such as lab coats, gloves, and safety glasses.

Is 7-Hydroxy-4-Methylcoumarin Toxic

7 Hydroxy 4 methylcoumarin powder (4-Methylumbelliferone, 4-MU) is generally considered low toxicity, but like all chemicals, it should be handled carefully. Here's a more detailed look at its toxicity and safety profile:

1. Toxicity:

Acute Toxicity: Studies have shown that 4-MU has relatively low acute toxicity. For example, the oral LD50 (lethal dose for 50% of the population) in rats is relatively high, indicating that it requires a large dose to cause acute toxicity.

Chronic Toxicity: There is limited data on the chronic toxicity of 4-MU. However, given its widespread use in research and medicine, it is generally considered to be of low chronic toxicity when used at appropriate concentrations.

Carcinogenicity and Mutagenicity: No significant evidence suggests that 4-MU is carcinogenic or mutagenic. However, comprehensive long-term studies are limited.

2. Safety and Handling:

Personal Protective Equipment (PPE): When handling 4-MU, it is recommended to use appropriate PPE, such as gloves, lab coats, and safety goggles, to avoid skin and eye contact.

Ventilation: To prevent breathing in dust or fumes, work in an area with good ventilation.

Avoid Ingestion and Inhalation: Do not ingest or inhale the compound. In the event of an unintentional inhalation or ingestion, get medical help right away.

First Aid Measures:

Skin Contact: Use a lot of soap and water for washing. Seek medical advice if irritation develops.

Eye Contact: Rinse with water for a few minutes, being cautious. If contact lenses are present and easily removed, do so. Continue rinsing and seek medical attention if irritation persists.

Ingestion: Do not induce vomiting. Rinse your mouth out, then get help right away.

Inhalation: Move the person to fresh air. If they are not breathing, give artificial respiration and seek medical help.

3. Environmental Impact:

More information is needed on the environmental impact of 4-MU. It is advisable to prevent it from entering waterways and to dispose of it by local regulations.

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

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Packing

Logistics Update

In addition to guaranteeing product quality, the other most vital thing is that clients receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ

1. How to inquire?

We can be reached by phone, email, or social media.

2. How do you guarantee the quality of products?

Each batch must be tested, and COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We cooperate with third parties as well, like SGS.

3. How do you pack and store?

Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.

Storage: You can keep it in a dry and cool place and make it avoid sunlight.

If you want to know about the 7 Hydroxy 4 methylcoumarin powder, you can contact Xi'an Sonwu. Click the email, and then you get high-quality 4 MU powder.

Email: sales@sonwu.com

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