Cycloastragenol Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of cycloastragenol powder in China. We warmly welcome yuo to wholesale bulk cycloastragenol powder for sale here from our factory. Quality products and reasonable price are available.

What Is Cycloastragenol CAG
Cycloastragenol powder, triterpenoid saponins, is mainly obtained by hydrolyzed Astragalus IV. Cycloastragalus alcohol is the only activator of telomerase found to delay telomere shortening by increasing telomerase.
Astragalus membranaceous is one of the commonly used traditional Chinese medicinal materials. Raw can benefit the body, strengthen the surface, and diuresis, reduce swelling, detoxify, and promote muscle growth; Studies have shown that Astragalus and its saponins have significant immune regulation, anti-inflammation, anti-oxidation, anti-ischemic brain damage, anti-aging, and nootropic effects. In-depth research on astragalosides has been made at home and abroad, and dozens of astragalosides have been isolated and identified, such as acetyl astragaloside I, astragaloside I, II, astragaloside I-VIII, etc., astragaloside B, and astragaloside I-XVI . Astragaloside IV is a representative saponin component of the traditional Chinese medicine Astragalus, and cycloastragenol is a saponin of Astragaloside IV. Cycloastragenol is the primary hydrolysis metabolite of astragaloside in the intestinal tract, and the component is absorbed into the blood. It has a relatively small molecular weight and strong lipophilicity, which is conducive to biofilm penetration and gastrointestinal absorption to achieve better bioavailability. Many modern medical studies have proved that CAG has a significant telomerase activation effect. It is one of the raw materials for functional cosmetics and nutritional foods, and it is currently the only raw material that can activate telomerase in human cells. It is an excellent anti-aging substance. The availability of Cycloastragenol is pervasive, so if you need pure Cycloastragenol, don't hesitate to get in touch with Xi'an Sonwu online.

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Where To Buy CAG
Xi'an Sonwu Biotech Co. ltd. is an affluent experience manufacturer and distributor. It has extensive and stable cooperation with countries in the Americas, Asia, Europe, and Oceania worldwide. Xi'an Sonwu has always insisted on product quality first. Serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from selecting raw materials and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need plant extract, please contact Xi'an Sonwu.
Xi'an Sonwu ultimately makes specific products quality and also supplies samples. Here is the quantity.

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OEM Service
Xi'an Sonwu not only can supply raw powder but also capsules. So customers could customize capsules and the following items.
1. Customized capsules shells ( color, size, material)
2. Customized bottles( color, size, material, style)
3. Customized packaging(vacuum sealed foil packaging, box, drum)
4. Customized label(optical mask, paint film, matte film )

What Are The Benefits Of Cycloastragenol
1. Anti-aging effect
There are many theories about aging, among which the telomere theory is the most influential, and the telomere theory includes two kinds of telomere and telomerase. Telomere is a unique structure at the end of chromosomes, which has a protective effect on chromosomes and shortens chromosome replication and cell division. Cells also age as telomeres shorten. Telomerase can synthesize telomeres and stabilize the length and structure of telomeres, thereby protecting chromosomes and delaying cell aging. With the continuous deepening of research on telomeres and telomerase, it is found that if telomerase is activated, the number of cell divisions can increase and prolong the life span. Therefore, finding an effective telomerase activator is the key to anti-aging. Cycloastragenol powder can lengthen shortened telomeres and improve the health span of adult mice or aged mice without increasing the incidence of disease; in addition, Cycloastragenol has effects on D-galactose-induced aging mice Anti-aging effect, the results showed that Cycloastragenol has a significant anti-aging effect, and its possible mechanism is to increase the activity of total superoxide dismutase (T-SoD) and total antioxidant capacity (T-A0C) and reduce malondialdehyde (MDA) and hydroxyproline (HYP) content.

2. Antiviral effect
Cells of the immune system need to undergo many division processes in carrying out their physiological functions, so they show low telomerase activity. Studies have shown that when immune-competent T cells are stimulated, they can upregulate telomerase activity through T cell antigen receptors or mitogens, and their strength can reach the level of tumor cells. Another study shows that the reduction of telomerase activity will lead to the premature decline of the immune system, so the activation of telomerase activity in T cells has become one of the focuses of antiviral research. TA-65 and HTA in Astragalus extract significantly affect the proliferation activity of human CD4 T cells and CD8 T cells, and telomerase. The results show that TA-65, the extract of Cycloastragenol, has a noticeable telomerase activation effect; The enhancement of telomerase is associated with the significant enhancement of T cell ability, which can reduce the production of HIV. It showed that TA-65 has the potential ability to treat HIV and other diseases that need to enhance the activity of telomerase in T cells.

3. Protect lung injury
Idiopathic pulmonary fibrosis is a fatal chronic disease with unknown etiology, insidious onset, and last exacerbation. In recent years, some scholars have found through research that the generation of IPF may be related to the shortening of telomeres, and the length of telomeres in patients' white blood cells is 231 shorter than that of ordinary people. Based on a mouse model of idiopathic fibrosis, Le Saux et al. studied the effect of Cycloastragenol on fibrosis in bleomycin-induced mTOR heterozygous mice. In the study, the experimental group treated with Cycloastragenol significantly inhibited the process of pulmonary fibrosis through telomerase activation and reduced the accumulation of senescent cells in the lungs. In vitro studies on the therapeutic effect of Cycloastragenol on small airway epithelial cells or pulmonary fibrosis showed that telomerase activation and prolonging replicative lifespan were only achieved in epithelial cells, suggesting the mechanism by which Cycloastragenol protects lung injury involves specific types of lung cells. Therefore, the telomerase activator has the potential to treat idiopathic pulmonary fibrosis.

4. Antidepressant effect
Some scholars have recently proposed that it can judge chronic stress, depression, schizophrenia, and other diseases by observing the telomere length of peripheral blood lymphocytes. Delaying the shortening of telomeres or extending them can theoretically prevent or even treat the above conditions. CAG can activate the activity of telomerase, promote the proliferation of neonatal cuticle cells, and especially promote the wound healing of neonatal cuticles in vitro. At the same time, it can induce telomerase activity and the activation of Cyclophosphoside response element binding protein (CREB) in PC12 cells and primary neurons. Oral administration of CAG to experimental mice for seven consecutive days showed that it could effectively alleviate their depressive behaviors, suggesting excellent development potential in treating depression.

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate Stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

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Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

FAQ
Despite the long history of use of Astragalus extract, there are minimal reports on astragal, the aglycone ring of most astragalus saponins. In terms of research on the activity of Cycloastragenol, in addition to the reported effects of anti-aging, anti-virus, protection of lung injury, anti-depression, and anti-hyperlipidemia, further research is required to prepare it into a drug and apply it to practice. In addition, Cycloastragenol structural analogs obtained through hydrolysis and biocatalysis may also have certain biological activities, which is a direction for future research. It showed that Cycloastragenol has a broad research space and a good market development prospect.
If you want to know a Cycloastragenol manufacturer, you can contact Xi'an Sonwu. Click the email then you get high-quality Cycloastragenol powder.
Email: sales@sonwu.com

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