Bakuchiol Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of bakuchiol powder in China. We warmly welcome yuo to wholesale bulk bakuchiol powder for sale here from our factory. Quality products and reasonable price are available.

Bakuchiol Products
Bakuchiol powder is a phenolic substance extracted from the herbaceous plant psoralen. It is the main component of the volatile oil of commonly used traditional Chinese medicine Bakuchiol, accounting for more than 60%. It is a prenyl phenolic terpene compound. Bakuchiol regulates gene expression in a way similar to retinol and thus produces the same effect. When used in combination with retinol, it has also been shown to stabilize retinol. Other benefits of bakuchiol include antioxidant, anti-inflammatory, antibacterial, anti-tumor, liver protection, melanin suppression, etc. It is a natural and safe alternative to retinol.
Scientific research shows that bakuchiol can control oil, anti-acne, anti-bacteria, and anti-inflammation, even better than A-alcohol, so it is very suitable for acne patients and oily skin. Secondly, it can use to treat dark yellow skin and post-inflammatory pigmentation. Its whitening principle inhibits the activity of tyrosine mycophenolate and diphenols to achieve a particular whitening effect. Furthermore, it is a more robust fat-soluble antioxidant than vitamin E. It can inhibit lipid peroxidation induced by free radicals, prevent ultraviolet rays from damaging the skin, and delay cell apoptosis. And by reducing the decomposition of collagen and promoting the synthesis of collagen, it has also been medically proven to have sound anti-aging effects. As the research on bakuchiol advances, there are more and more bakuchiol-containing products on the market, so whether you need raw bakuchiol or liquid, you can directly search for Xi'an Sonwu.

Certificate Of Analysis

Where To Buy Bakuchiol
Xi'an Sonwu Biotech Co. ltd. has more than ten years of experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. And strictly control product quality, which means selection starts from raw materials. So please look for Xi'an Sonwu Biotech Co. ltd. when buying bakuchiol.
Xi'an Sonwu can ultimately ensure product quality and offer samples. Here is the quantity.

Customers' Good Comment

OEM Service
Xi'an Sonwu not only can supply pure powder but also liquid.
So any customers could customize the following items.
1. Customized bottles(size, color, material, style)
2. Customized packaging(vacuum foil packaging, box, drum)
3. Customized label(paint film, matte film, optical mask)

What Is Bakuchiol Good For
1. Hypoglycemic and lipid-lowering effects
Animal experiments have shown that bakuchiol can effectively reduce the blood sugar level of hereditary and non-hereditary dB/dBII type diabetic mice and can improve hyperlipidemia caused by diet. In vitro experiments confirmed that bakuchiol can inhibit protein tyrosine phosphatase 1B (PTP1B), negatively regulating insulin signaling. Therefore, it is expected to use bakuchiol for targeted therapy of diabetes.

2. Anti-inflammatory effect
Studies have found that bakuchiol can effectively inhibit the production of NO and prostaglandin Er in RAW 264.7 macrophages induced by interferon-γ lipopolysaccharide, and the inhibition rates of the two are 53.7% and 84.2%, respectively, at 50 μmol.L-1. %. However, some studies have found that when the concentration of bakuchiol is 10 μmol.L-1, the NO production of mouse peritoneal macrophages activated by lipopolysaccharide is only weakly inhibited. The concentration is higher than 30 μmol.L-1 produces cytotoxicity. Bakuchiol is a natural inhibitor of leukocyte function, which can control the production, migration, and degranulation of eicosanoids in inflammatory sites, and dose-dependently reduce the formation of leukotrienes and leukotrienes in human neutrophils and platelet microsomes. Thromboxane is a weak inhibitor of secreted intracellular phospholipases.

3. Antibacterial effect
Bakuchiol powder can significantly inhibit the growth of Staphylococcus aureus and, Staphylococcus epidermidis, Propionibacterium acnes. It can effectively reduce the scars left by acne and significantly improve skin condition. Clinical trials have shown that bakuchiol will not cause skin irritation or dryness and can be used together with other anti-acne ingredients in the cosmetics industry. In addition, psoralen phenol is effective on various oral microorganisms, such as Streptococcus mutans, Streptococcus haematococcus, Streptococcus salivarius, Streptococcus caries, Enterococcus faecalis, Enterococcus faecalis, Lactobacillus acidophilus, Lactobacillus Plantarum, actinomyces mucilis, Lactobacillus casei, etc., all have apparent inhibitory effects. Therefore, bakuchiol has excellent potential to be used in food additives and mouthwashes for the prevention and treatment of dental caries.

4. Antioxidant and Liver Protective Effects
Bakuchiol can inhibit reduced coenzyme II (NADPH), ascorbic acid, and tert-butanol peroxide.CCl4. Induced lipid peroxidation in liver microsomes and NADPH-dependent and ascorbic acid-induced mitochondrial lipid peroxidation. It inhibits oxygen consumption induced by lipid peroxidation in a time-dependent manner and is a potential microsomal antioxidant. Bakuchiol can not only induce the apoptosis of hepatic stellate cells/myofibroblasts through the caspase-3-dependent pathway, thereby reversing the formation of liver fibrosis and cirrhosis, but also Reduces hepatotoxicity induced by cholinesterase inhibitors such as text-butylammonium oxide, CCI4, and D-galactosamine by inhibiting lipid peroxidation and intracellular glutamate depletion.

5. Antidepressant effect
Patents have shown that bakuchiol compounds do not affect the activity of the r-aminobutyric acid transporter and L-glutamate transporter due to their ability to selectively inhibit the dopamine transporter, norepinephrine transporter, and serotonin transporter. It has no effect, so it has the potential to treat depression. Animal experiments show that the antidepressant effect of bakuchiol is significantly better than that of clinical antidepressant bupropion hydrochloride, which shows that bakuchiol compounds can potentially treat psychosis clinically. It has a good market prospect in terms of diseases and neurological diseases.

6. Estrogenic effect
Many studies have shown that the petroleum ether part of psoralen has estrogen-like effects, and bakuchiol is one of its active ingredients. Bakuchiol has a certain degree of agonistic effect on the two subtypes of estrogen receptor (ER) a and β, and its affinity for ERa is five times higher than ERβ. Based on the estrogen-like effect of psoralen, some Studies have found that bakuchiol can prevent and treat osteoporosis caused by estrogen deficiency. Animal experiments have confirmed that bakuchiol can treat osteoporosis caused by a lack of estrogen in a postmenopausal female mouse model simulated at low doses. It has been found that its estrogen-like effect achieves a therapeutic purpose by inhibiting bone resorption.
 

Is Bakuchiol A Functional Analogue Of Retinol
Early research suggests that bakuchiol regulates gene expression in a way that retinol does and therefore produces the same effect. ​​Bakuchiol is considered a natural alternative to retinol and can be used to reduce the signs of skin aging, especially for sensitive and oily skin.
There is a 12-week, double-blind study in which 44 subjects received either bakuchiol or retinol twice daily. After use, high-resolution facial photos of issues at 0, 4, 8, and 12 weeks were acquired and analyzed using a photo analysis system. Subjects were also required to undergo a tolerability assessment after use to review the side effects of the two ingredients. During study visits, a board-certified dermatologist rated subjects' facial pigmentation and redness grades. Bakuchiol and retinol can reduce the surface area of fine facial wrinkles compared to the baseline. At the 12-week time, significant changes in the wrinkled surface area from baseline were found, but there were no apparent differences between bakuchiol and retinol.
When retinol: bakuchiol = 1: 2, it can resist the oxidation of active oxygen on retinol;
When retinol: bakuchiol = 1: 4, retinol can be photostable. That is, it can use during the day.

Bakuchiol extracted from plants is a potential antibacterial substance, and its anti-oxidation and anti-inflammatory effects are better than retinol. For oily acne-prone skin, it is a long-lasting player. For example, the squalene in the skin is easily oxidized under ultraviolet radiation, leading to keratinization of the skin; keratinocytes block the pores and then form acne to clog the pores. On this issue, bakuchiol will exert a more robust fat-soluble antioxidant than vitamin E, which can protect the skin sebum from oxidation and prevent hair follicles from clogging the skin. Also, retinol is not recommended for pregnant women, but bakuchiol does not have this warning. In conclusion, bakuchiol is comparable to retinol in improving photoaging and is better tolerated than retinol. Bakuchiol holds promise as a more tolerated alternative to retinol.

Bakuchiol Side Effects
Bakuchiol is considered a safer, milder option compared to retinoids. It's a plant-based, utterly natural compound that most cases, won't cause dryness or irritation. And can also be used for sensitive skin.
Experience any adverse side effects such as redness, burning, or stinging after using a bakuchiol product. You may be sensitive to the compound or other ingredients in the formula, so discontinue use if you notice these. Bakuchiol is safe relative to retinol during pregnancy, but to be safe, you should consult your midwife or doctor before adding it to your skin care regimen.

Factory
1. Xi'an Sonwu Biotech Co., Ltd has adequate stock because it has its factory to produce, manufacture and store the products. Xi'an Sonwu has a strict-ordered, clean, and tidy production section. Under Xi'an Sonwu, researchers can continuously develop pure new products.
2. Xi'an Sonwu has strict requirements for talent accomplishment. To ensure every product is escorted, rigorous data support and after-sales service are provided.

Certificate

Package

Logistics

Xi'an Sonwu is not only guaranteeing product quality and also assists customers in receiving the goods smoothly. Therefore, Xi'an Sonwu supplies all kinds of couriers according to different customers' needs.

FAQ
If you want to know a bakuchiol manufacturer, you can contact Xi'an Sonwu. Click the email then you get high-quality bakuchiol powder.
Email: sales@sonwu.com

Hot Tags: bakuchiol powder, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, raw, supply, for sale, Black Pepper Extract Powder, Epicatechin Powder, Polygonum Cuspidatum Extract Resveratrol, Pure Resveratrol Powder, Yohimbe Extract Powder, Berberine Hcl Powder