Coluracetam Supplement

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of coluracetam supplement in China. We warmly welcome yuo to wholesale bulk coluracetam supplement for sale here from our factory. Quality products and reasonable price are available.

What Is Coluracetam

Coluracetam supplement is a nootropic supplement that has gained popularity in the field of cognitive enhancement. It is derived from the racetam family of compounds and is known bfor its chemical name MKC-231. Developed in Japan by the Mitsubishi Tanabe Pharma Corporation, coluracetam was originally intended as an experimental treatment for Alzheimer's disease. However, its potential cognitive-enhancing effects have led to its popularity as a nootropic supplement.

It is believed to modulate choline uptake and potentially affect glutamate receptors, influencing cognitive processes such as memory and attention.

Coluracetam is available in coluracetam powder and capsule forms. The dosage of it can vary depending on individual response and the desired effects. Typical doses range from 10 mg to 80 mg per day, but it is recommended to start with a low dose and gradually increase as needed.

The purity of our company's coluracetam powder can reach 98%. Also, our prices are very competitive compared to other companies. If you want to know more, don't hesitate to get in touch with Xi'an Sonwu Biotech Co. Ltd.

Coluracetam Buy

Xi'an Sonwu has rich experience in the global trade and health industry. Reputation-based quality first is the principle of Xi' an Sonwu Company. Xi'an Sonwu strictly controls product quality, so the selection of materials starts with raw materials. Also, we handle every detail and minimize costs so our clients can get the most cost-effective products. Based on these, customers have given high praise to our products. If you need coluracetam supplement, find Xi’an Sonwu Biotech Co. Ltd.

We ultimately make sure of the product’s quality so that samples can be supplied. Here is the quantity.

Customers' Good Comment

OEM Service

Xi'an Sonwu not only can supply high-quality nootropic coluracetam powder, but also supply its capsules.

So any customers could customize the capsules they want. And items below can be supplied.

Customized capsules shells (size, color, material)

Customized bottles(size, color, material, style)

Customized packaging(vacuum foil packaging, box, drum)

Customized label(paint film, matte film, optical mask)

What Is the Mechanism of Action of Coluracetam

Coluracetam is a nootropic compound known for its potential cognitive-enhancing effects. It is believed to act on multiple neurotransmitter systems in the brain, particularly those involving acetylcholine.

One of the mechanisms of action of coluracetam is to promote high-affinity choline uptake (HACU) by cholinergic neurons. Choline is an important precursor for the synthesis of acetylcholine, a neurotransmitter involved in learning, memory and cognitive processes. By increasing HACU, coluraacetam enhances the availability of choline in the brain, potentially leading to increased acetylcholine synthesis and release. This may help improve cognitive function, memory formation, and concentration.

In addition to its effects on choline absorption, coluracetam has been shown to bind to the choline transporter (CHT) and modulate its function. CHT is responsible for the reuptake of choline from the synapse following ACh release. By interacting with CHT, coluraacetam increases choline recycling, ensuring a steady supply of choline for ACh synthesis. This mechanism further supports the enhancement of cholinergic neurotransmission and its associated cognitive benefits.

Furthermore, coluracetam modulates glutamatergic neurotransmission. Glutamate is the major excitatory neurotransmitter in the brain, involved in many cognitive processes. Coluracetam has been reported to enhance the activity of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, ion channels responsible for mediating rapid excitatory neurotransmission. By upregulating AMPA receptors, coluracetam enhances synaptic plasticity, improves neuronal communication, and promotes memory formation.

Another proposed mechanism of action for coluracetam involves its interaction with the sigma-1 receptor. The sigma-1 receptor is a protein found in various regions of the brain, including those involved in memory and emotion regulation. Activation of sigma-1 receptors is associated with neuroprotection, regulation of calcium channels, regulation of neurotransmitter release, and promotion of neurite outgrowth. Coluracetam has been shown to bind to and increase the density of sigma-1 receptors, which may lead to the modulation of these various processes.

Coluracetam also showed potential neuroprotective effects. It has been observed to increase the production of brain-derived neurotrophic factor (BDNF) in certain brain regions. BDNF is a growth factor that supports neuronal survival, growth and differentiation. By increasing BDNF expression, coluracetam promotes neuronal health and supports the maintenance of cognitive function.

What Is Coluracetam Used For

1. Memory Enhancement: Coluracetam has been suggested to improve memory formation and retention. It may enhance the release and synthesis of acetylcholine, an important neurotransmitter involved in memory processes. By increasing the availability of acetylcholine in the brain, coluracetam may support better memory recall and learning abilities.

2. Cognitive Function: Coluracetam has shown promise in enhancing overall cognitive function. It may improve focus, attention, and mental processing speed. This may be due to its effects on cholinergic and glutamatergic neurotransmission, which are essential for cognitive processes such as learning, problem-solving, and decision-making.

3. Mood Enhancement: Some users report a potential mood-boosting effect with coluracetam. It may have anxiolytic properties, helping to reduce anxiety and improve overall mood. While the exact mechanisms behind these effects are not fully understood, coluracetam's interaction with the sigma-1 receptor has been proposed to contribute to its anxiolytic properties.

4. Neuroprotective Effects: Coluracetam has been studied for its potential neuroprotective properties. It may increase the production of brain-derived neurotrophic factor (BDNF), a protein essential for neuronal survival and growth. By supporting neuronal health, coluracetam may help protect against cognitive decline and age-related neurodegenerative disorders.

5. Visual Acuity: Some research suggests that coluracetam may have a positive impact on visual perception. It has been investigated for its potential in improving visual acuity and enhancing visual recognition.

6. Attention Deficit Hyperactivity Disorder (ADHD): Coluracetam has shown potential benefits in individuals with ADHD. It may help improve attention and focus, reduce impulsivity, and enhance cognitive performance. However, more research is needed to establish its efficacy and safety for this specific population.

7. Neuronal Regeneration: Coluracetam has sparked interest for its potential in promoting neuronal regeneration. It has been studied in preclinical models of brain injury and neurodegenerative conditions, showing promising results in stimulating neuronal regrowth and repair.

8. Anti-depressive Effects: Limited research suggests that coluracetam may have anti-depressive effects. By modulating neurotransmission and potentially influencing mood-regulating systems, coluracetam may help alleviate symptoms of depression. However, further research is necessary to confirm these findings.

Coluracetam Side Effects

Here are some of the reported side effects associated with coluracetam:

1. Headache: Headache is one of the most commonly reported side effects of coluracetam. It is believed to be a result of increased cholinergic activity in the brain. In most cases, headaches are mild and transient, resolving on their own without the need for intervention.

2. Gastrointestinal Disturbances: Some users have reported gastrointestinal distress, including stomach discomfort, nausea, or diarrhea. These effects are generally mild and short-lived, but if they persist or worsen, it is important to seek medical advice.

3. Insomnia or Sleep Disturbances: Some individuals have reported experiencing difficulty falling asleep or changes in sleep patterns while taking coluracetam. This may be due to the stimulating effects of the drug. It is recommended to avoid taking coluracetam in the evening to minimize any potential sleep disturbances.

4. Nervousness or Anxiety: While coluracetam is often reported to have anxiolytic properties, a paradoxical effect of increased nervousness or anxiety has been reported in some individuals. If these symptoms arise and become bothersome, it is advisable to discontinue use and consult a healthcare professional.

5. Dizziness or Lightheadedness: Some users have reported feelings of dizziness or lightheadedness while taking coluracetam. These side effects are generally mild and temporary, but if they become persistent or severe, medical attention should be sought.

6. Fatigue or Sedation: In some rare cases, individuals have reported increased fatigue or feelings of sedation. This may be a result of individual biological differences and the way the drug interacts with the central nervous system. If such symptoms occur and affect daily functioning, it is recommended to discontinue use and consult a healthcare professional.

Factory

Xi'an Sonwu is located in a place with a beautiful natural environment, covering an area of 10,000 square meters. The factory has advanced production equipment, and the technical team is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers insist on developing new products. The following is the testing environment of our laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for our products and providing our customers with a quality experience.

Certificate

Packaging

Recent Logistics Record

In addition to guaranteeing product quality, the other most vital thing is clients can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

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FAQ

1. How to inquiry?

You can contact us by email, telephone number, or social media.

2. How to guarantee the quality of products?

Each batch needs to be tested so we can supply COA for customers. Additionally, our products pass the test: HPLC, UV, GC, TLC, etc. And we also cooperate with third parties, like, SGS.

3. How to pack and store the product?

Pack: Vacuum sealed foil packaging & Sealed export grade drum or pack according to customers' need

Storage: For a short time, you can keep it in a dry and cool place and make it avoid sunlight.

If you are interested in our company's coluracetam supplement, please contact Xi'an Sonwu Biotech Co. Ltd.

Email: sales@sonwu.com

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