Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of 7,8-dihydroxyflavone nootropic in China. We warmly welcome yuo to wholesale bulk 7,8-dihydroxyflavone nootropic for sale here from our factory. Quality products and reasonable price are available.
What Is DHF Nootropic
7,8-dihydroxyflavone nootropic is a synthetic flavonoid compound, also called 7,8-DHF or tropoflavin . One study found it activates small molecules of a specific receptor called tropomyosin-associated kinase B (TrkB). This receptor binds to a peptide called brain-derived neurotrophic factor, which plays a vital role in the growth and protection of neurons. While BDNF itself cannot be used for therapeutic purposes due to poor absorption into the brain, 7,8-DHF is a potent mimic of BDNF that can act on TrkB similarly. Therefore, it could produce a similar effect to BDNF in the brain and be more therapeutically beneficial due to its better absorption and ability to cross the blood-brain barrier. In animal models of cognitive decline such as Alzheimer's and aging, 7,8-DHF has shown an ability to promote the growth of dendrites. These extensions of neurons help them communicate with other neurons. This neuronal extension can help to restore communication between neurons and improve cognitive function. In addition to its effects on neuron growth and protection, 7,8-DHF has also demonstrated antioxidant and anti-inflammatory effects. It can scavenge intracellular and extracellular free radicals, inhibit oxidative stress reactions, protects cell membranes and DNA, and inhibit the release of various inflammatory mediators. These pharmacological effects make tropoflavin a promising candidate for treating nervous system diseases, cardiovascular diseases, inflammation, and other conditions. If you are interested in 7,8-DHF or obtaining pure 7,8-DHF for research purposes, you can contact Xi'an Sonwu for more information.
Certificate Of Analysis
ANALYSIS | SPECIFICATION | RESULT |
Appearance | Yellow powder | Conform |
Loss on Drying | ≤0.50% | 0.36% |
Residue on Ignition | ≤ 0. 10% | 0.07% |
Heavy Metals | ≤10ppm | <10ppm |
Max Single Impurity | ≤0. 10% | Conform |
Total Impurities | ≤0. 10% | 0. 04% |
Melting Point | 243-246°C | 244C |
Boiling Point | 494.4±45.0 °C(Predicted) | 0. 15% |
Solubility | DMSO: soluble24mg/Ml | Conform |
Pb | ≤3.0ppm | Conform |
Hg | ≤1.0ppm | Conform |
Microbiological Tests | ||
Total Plate Count | ≤1000cfu/g | Conform |
Total Yeast & Mold | ≤100cfu/g | Conform |
Assay (HPLC) | 99.0% | 99.37% |
Where To Buy 7,8-Dihydroxyflavone
Xi'an Sonwu Biotech Co. Ltd. is a manufacturer and distributor with more than ten years of experience. It has extensive and stable cooperation with countries worldwide in the Americas, Asia, Europe, and Oceania. Xi'an Sonwu has always insisted on product quality first; serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from the selection of raw materials, and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to handle every detail to minimize costs and allow customers to get products with high-cost performance. Based on these, customers have given good feedback on the product. So if you need nootropics powder and capsules, please contact Xi'an Sonwu.
Xi'an Sonwu ultimately makes sure of the product quality and supplies the samples. Please check the quantity.
7,8-Dihydroxyflavone Form | Sample Amount | MOQ |
Powder | 10g | 10g |
Bulk capsules | 200 capsule | 200 capsule |
Bottle capsules | 5 bottles | 5 bottle |
Customers' Good Comment
OEM Service
Xi'an Sonwu not only can supply high-quality dihydroxyflavone powder and dihydroxyflavone capsules.
So any customers could customize the capsules they want. And items below can be supplied.
1. Customized capsules shells (size, color, material)
2. Customized bottles(size, color, material, style)
3. Customized packaging(vacuum foil packaging, box, drum)
4. Customized label(paint film, matte film, optical mask)
What Is 7 8 Dihydroxyflavone Research
7,8-dihydroxyflavone nootropic is a naturally occurring flavonoid compound that has got much attention recently due to its various pharmacological effects. Numerous experimental studies have been conducted to investigate the potential therapeutic applications of this compound.
One of the most well-studied pharmacological effects of tropoflavin is its neuroprotective activity. In a study, the researchers investigated the effects of tropoflavin on dopaminergic neurons in an animal model of Parkinson's disease. They found that treatment with tropoflavin significantly protected the dopaminergic neurons from degeneration and improved motor function. This research suggests that it may hold promise for treating Parkinson's disease.
In addition to its neuroprotective benefits, it has also proof have antidepressant and anxiolytic effects. In a study studying tropoflavin in a mouse model of depression, the researchers found that treatment with tropoflavin increased serotonin levels in the brain, a common target for antidepressant drugs. A separate study found that tropoflavin had anxiolytic effects in animal models of anxiety.
Another interesting pharmacological effect of tropoflavin is its cardioprotective activity. There also have some research on the effects of 7, 8-dihydroxyflavone on cardiac function in animals with heart failure. They found that treatment with 7, 8-dihydroxyflavone reduced cardiac fibrosis and improved heart function. The study suggests that it may hold promise as a treatment for heart failure.
What Are The Side Effects Of Dihydroxyflavone
While tropoflavin has many potential benefits, like any medication or supplement, it may also have side effects.
Liver toxicity: One potential side effect of tropoflavin is liver toxicity. High doses of tropoflavin caused liver damage in mice and reduced liver function in rats.
Weight loss: Another potential side effect of 7,8-Dihydroxy flavone is weight loss. Treatment with tropoflavin resulted in weight loss in rats. However, this effect was only observed in very high compound doses.
Skin rash: Use tropoflavin caused skin rash in mice. However, it was just a mild effect and did not lead to any serious adverse events.
Potential drug interactions: Tropoflavin may interact with CYP3A4, a liver enzyme metabolizing many drugs. This interaction may affect the efficacy or toxicity of drugs metabolized by CYP3A4.
7 8-Dihydroxyflavone Dosage
In preclinical studies, researchers typically administer tropoflavin to animal models at doses ranging from 1 mg/kg to 30 mg/kg of body weight per day, depending on the specific study and animal model used.
Oral ingestion does appear to have effects, with rat studies noting:
5mg/kg is effective in the cognitively unwell mouse (chronic usage)
10mg/kg is effective in the cognitively well rat (subchronic use)
30mg/kg in the mouse being acutely effective
If tropoflavin is ever approved for human use, the prescribing physician would determine the dosage and administration guidelines based on the patient's medical condition and other factors, including age, weight, and overall health.
As a dietary supplement, 25 mg of tropoflavin powder is recommended once or twice a day.
Factory
1. Xi'an Sonwu Biotech Co., Ltd owns a factory where the products are produced, manufactured, and stored, thus ensuring there is adequate stock available. The production department of Xi'an Sonwu is well-organized, clean, and tidy, enabling researchers to develop high-quality new products continuously.
2. To ensure that each product is of the highest quality, Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. In addition, Xi'an Sonwu provides rigorous data support and after-sales service to guarantee that each product is well-supported and accompanied throughout the entire process.
Certificate
Package
Logistics
Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
FAQ
Characteristics of tropoflavin
Tropoflavin is a naturally occurring flavonoid compound with the molecular formula C15H10O4.
1. Stability: It is relatively stable under normal conditions but can be degraded by exposure to light and air.
2. Pharmacological effects: It has been shown to have various pharmacological effects, including antioxidant, anti-inflammatory, and neuroprotective effects. It has also studied therapeutic effects on conditions ranging from neurological disorders to lesion cells.
3. Safety: While tropoflavin has not been extensively studied in humans, preliminary studies suggest a relatively low toxicity profile.
If you want to know a DHF manufacturer, you can contact Xi'an Sonwu. Click the email then you get high-quality 7,8-dihydroxyflavone nootropic powder.
Email: sales@sonwu.com
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