What Is Acetyl Hexapeptide 38
Acetyl Hexapeptide 38 powder is a scientifically formulated peptide used in anti-aging skincare to help relax facial muscles that contribute to expression lines. En entravant la libération de neurotransmetteurs au niveau de la jonction neuromusculaire, elle diminue la contraction musculaire, lissant visiblement les rides dynamiques comme celles du front, des glabelles et des pattes d'oie. Compared to neurotoxin injections, it is a gentler, localized, and non-invasive treatment that requires continued use for gradual results. It is primarily used in anti-aging skincare products. If you are interested in Acetyl Hexapeptide-38, please feel free to contact Xi'an Songwu. Below is its biological structure and explanation.
1. Structure
Hexapeptide: C'est une structure en forme de chaîne composée de six acides aminés (les éléments constitutifs des protéines). Its specific sequence is Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂.
Acetyl Group: An acetyl group (CH₃CO-) is attached to the N-terminus (starting end) of the peptide chain. This modification enhances the peptide chain's stability and skin permeability.
2. Acetyl Hexapeptide 38 is not:
It is not Botox and does not paralyze muscles. Its effects are not as deep or as strong as Botox, resulting in a milder effect.
It is not a filler, but it does increase skin hydration, firming, and radiance.
If this product is discontinued, its effects will gradually diminish as muscle contraction returns to normal. Long-term use is recommended.
What Are The Effects Of Acetyl Hexapeptide 38
Acetyl Hexapeptide 38 is a bioactive peptide commonly used in anti-ageing skincare products, with its primary benefits focused on improving skin texture and reducing signs of ageing. Here is a detailed analysis of its main benefits:
1. Reduces dynamic wrinkles and expression lines
It targets wrinkles caused by repetitive movement of facial muscles (such as crow's feet, frown lines, and laugh lines). By interfering with the SNARE protein complex, which is essential for the release of neurotransmitters such as acetylcholine at the neuromuscular junction, it weakens the nerve signals transmitted to the facial muscles, causing some of them to relax.
This relaxation can smooth existing dynamic wrinkles (wrinkles visible when making expressions) and help prevent the formation of new wrinkles, as reduced muscle movement can slow the deepening of long-term wrinkles.
2. Improve skin smoothness and texture
By reducing wrinkle depth and fading fine lines, the skin's surface will become smoother and more even over time.
Regular use can improve the overall skin texture and make it feel softer to the touch.
3. Preventive anti-ageing effects
For younger people, it can help prevent the premature formation of deep wrinkles by limiting the excessive muscle contractions that lead to wrinkle formation.
It helps slow the transition from dynamic wrinkles (temporary wrinkles that appear when making expressions) to static wrinkles (permanent wrinkles that are visible when at rest).
4. Enhanced skin firmness
Indirectly, muscle relaxation and wrinkle reduction can lead to firmer, more radiant skin, especially in areas prone to sagging from repetitive motion (such as the eye area and forehead).
What Is The Mechanism Of Action Of Acetyl Hexapeptide 38
It targets the dermal-epidermal junction (DEJ) by strengthening the structural support between the dermis and epidermis. It serves as the foundation's "structural engineer" and is crucial for addressing ageing-related skin sagging and loss of elasticity. Here is a detailed analysis:
Core Mechanism: Strengthens the dermal-epidermal junction (DEJ), which is the key "anchoring area" connecting the epidermis to the dermis. Ageing weakens this structure, resulting in sagging skin, wrinkles, and a loss of elasticity. It addresses this problem in the following ways:
1. Stimulates key structural proteins:
Laminin synthesis: Laminin forms a "mesh" scaffold at the dermal-epidermal junction (DEJ) to ensure structural integrity.
Type IV and Type VII Collagen:
Type IV collagen stabilises the basement membrane.
Type VII collagen forms anchoring fibrils that "suture" the epidermis to the dermis.
Fibronectin: Enhances cell adhesion and tissue repair.
2. Promotes Elastin Production:
Tropoelastin (elastin precursor) improves skin elasticity and resilience.
3. Regulates Integrin Signalling:
Activates integrins (cell surface receptors) to enhance keratinocyte adhesion to the basement membrane.
4. Enhances Hemidesmosome Formation:
Promotes the assembly of hemidesmosomes - protein complexes that act as "rivets" connecting epidermal cells to the basement membrane.
Functional Results
By targeting these pathways, you can achieve:
Firmer, more lifted skin (less sagging in the cheeks/jowls).
Improved elasticity (skin "bounces back" faster).
Reduced static wrinkles (especially around the eyes/mouth).
Strengthens the skin barrier (by enhancing adhesion of the DEJ (dermal epidermal junction)).
Scientific Evidence
In vitro studies have shown increases in type IV collagen by 82%, laminin by 77%, and fibronectin by 141% (Sederma data).
Clinical trials show:
After 56 days, eye wrinkles were reduced by -32%.
Skin firmness increased by +19%.
Eye bags reduced by +24% (volume restoration).
If you would like to know the price of acetyl hexapeptide 38 powder, are interested in Xi'an Sonwu, or have other questions about the product, please do not hesitate to contact Xi'an Sonwu.
Email:sales@sonwu.com