What Is WS-5
WS5 powder, known as N-ethyl-p-menthane-3-carboxamide, is a synthetic cooling agent that is frequently used in a variety of consumer products to produce a cooling effect. This compound belongs to the family of menthol derivatives and is designed to be more effective and longer-lasting than natural menthol.
1. Critical Properties of WS-5:
Chemical Structure: N-ethyl-p-menthane-3-carboxamide.
Cooling Effect: WS-5 is known for its powerful and long-lasting cooling effect. It provides a more intense and longer-lasting cooling sensation than menthol.
Odor and Taste: Unlike menthol, WS-5 does not have a strong smell or taste, making it suitable for products that require a neutral profile.
2. Applications:
WS-5 is used in a variety of products to enhance the sensory experience by providing a cooling effect:
Oral Care: Toothpaste and mouthwash.
Food and Beverages: Chewing gum, candy, and other confectionery.
Personal Care: Skin care products, lotions, and shampoos.
Pharmaceuticals: Topical analgesics and cooling gels.
3. Benefits:
Enhanced Sensory Experience: Provides a powerful and long-lasting cooling effect without the minty solid taste of menthol.
Versatility: Its flavor profile and neutral scent make it appropriate for a variety of items.
Potency: Effective at low concentrations, which is cost-effective for manufacturers.
4. Comparison to other coolants:
WS-3: Provides a moderate cooling effect with a slight menthol smell.
WS-12: Known for its long-lasting cooling sensation and delayed onset.
WS-23: Provides a rapid cooling effect but for a shorter duration than WS-5.
5. Usage and Safety:
WS-5 is generally recognized as safe for use in consumer products when used by regulatory guidelines. Due to its high potency, it is typically used in minimal concentrations.
WS-5 is a versatile, powerful cooling agent used extensively in the oral care, personal care, food, and pharmaceutical industries. It is a well-liked option for boosting the sensory experience of a variety of products because of its capacity to deliver a powerful and prolonged chilling sensation without having a noticeable taste or odor.
What Is The Difference Between Ws-3 And Ws-5
WS-3 and WS-5 are synthetic cooling agents but have different properties and applications. Here's a detailed comparison between the two:
1. Chemical Structure:
WS-3: N-Ethyl-p-menthane-3-carboxamide.
WS-5: N-Ethyl-2,2,2-trifluoro-N-(p-tolyl)-acetamide.
2. Cooling Effect:
WS-3: Provides a moderate cooling sensation. The effect is noticeable but not as intense as WS-5. It offers a delayed onset of cooling that can last for a significant duration.
WS-5 is known for a more substantial and more sustained cooling effect than WS-3. It delivers a more intense and long-lasting cooling sensation.
3. Odor and Taste:
WS-3: Possesses a faint menthol flavor and aroma, which could affect the finished product's flavor character.
WS-5 Does not have a strong odor or taste, making it more suitable for applications with a neutral profile.
4. Applications:
WS-3: Commonly used in oral care products like toothpaste and mouthwash, as well as in chewing gum, candies, and skincare products. Its moderate cooling effect suits products requiring a less intense sensation.
WS-5: Widely used in oral care, food and beverages, personal care, and pharmaceuticals. Its solid and long-lasting cooling effect is ideal for products that aim to provide a more intense cooling sensation.
5. Usage Concentration:
WS-3: Generally used in lower concentrations because its cooling effect is moderate. Suitable for applications where a balanced cooling sensation is desired.
WS-5: Used in minimal concentrations due to its high potency. Effective in providing a solid cooling effect without significantly altering the product's flavor or odor.
6. Sensory Experience:
WS-3: Provides a gentle and prolonged cooling sensation, which can enhance the sensory experience without overpowering the product's primary characteristics.
WS-5: Offers a more pronounced and lasting cooling sensation, which can significantly enhance the sensory experience, especially in products that deliver a strong cooling effect.
7. Summary:
WS-3: Ideal for products requiring a moderate, balanced cooling effect with a slight menthol flavor.
WS-5: Best suited for applications needing a robust and long-lasting cooling effect with a neutral odor and taste.
The main differences between WS-3 and WS-5 lie in their intensity and duration of the cooling effect and their impact on the flavor and odor of the final product. While WS-5 is more intense and neutral and can be employed in more kinds of applications, WS-3 is mild and has a minor menthol impact.
How Do Cooling Agents Work
Cooling agents activate specific receptors in the skin and mucous membranes that are responsible for detecting cold temperatures. The primary mechanism involves the transient receptor potential melastatin 8 (TRPM8) ion channel, a key player in sensing cool and freezing temperatures. Here's how cooling agents achieve this:
Mechanism of Action:
1. Activation of TRPM8 Receptors: Cooling agents like menthol, WS-3, WS-5, and others bind to and activate TRPM8 receptors on sensory neurons in the skin and mucous membranes. This receptor is an ion channel that opens in response to cool temperatures or certain chemical compounds.
2. Ion Influx: When TRPM8 receptors are activated, they allow sodium and calcium ions to be influx into the nerve cells. This ion movement generates an electrical signal in the sensory neurons.
3. Signal Transmission: The electrical signals generated by the activated neurons are transmitted to the brain, where they are interpreted as a sensation of coolness or cold. This process is similar to how the body perceives actual cold temperatures.
If you want to know more about the WS5 manufacturer, you can contact Xi'an Sonwu. Click the email to get a high-quality WS 5 cooling agent.
Email: sales@sonwu.com