KY19382 Powder

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of ky19382 powder in China. We warmly welcome yuo to wholesale bulk ky19382 powder for sale here from our factory. Quality products and reasonable price are available.

What Is KY19382

KY19382 Powder (CAS 2226664-93-1) is a small molecule compound attracting attention in the scientific research field, primarily used as a potent activator of the Wnt/β-catenin signaling pathway. This compound significantly enhances the intracellular Wnt/β-catenin signaling pathway by simultaneously inhibiting the binding of CXXC5 to Dishevelled (Dvl) protein and inhibiting GSK-3β (glycogen synthase kinase-3β) activity. Since the Wnt pathway is a crucial pathway controlling hair follicle growth, stem cell activation, skin tissue repair, and regeneration, KY19382 has demonstrated significant biological effects in experimental studies. In cell and animal models, it promotes dermal papilla cell proliferation, extends hair shaft length in human or animal hair follicles, accelerates hair regeneration after hair removal in mice, speeds up healing in skin injury models, and even induces new hair follicle formation (follicular regeneration).

These results make KY19382 a potential candidate compound for hair regeneration and skin tissue engineering research. However, despite its promising potential in regenerative medicine, extensive safety, toxicology, and clinical studies are still needed to evaluate its actual application prospects.

Where To Buy KY19382

Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you want to buy KY19382 API.

Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.

Customers' Good Comment

How KY19382 Works

This product is a dual-acting Wnt/β-catenin pathway activator, meaning it turns on one of the body's key regenerative signaling pathways.
Its mechanism is based on two coordinated actions:

1. It blocks CXXC5–Dvl interaction (CXXC5 inhibitor)

CXXC5 is a negative regulator of the Wnt/β-catenin pathway.
It inhibits regeneration by binding to a protein called Dishevelled (Dvl).
KY19382 binds to CXXC5's interaction interface and prevents CXXC5 from suppressing Dvl.

Effect:
Wnt signaling becomes dis-inhibited (released from suppression)
More β-catenin accumulates in cells
Gene expression for regeneration is activated

This mechanism is especially important in:
hair-follicle regeneration
wound healing
stem-cell activation

2. It inhibits GSK-3β (Glycogen Synthase Kinase-3β)

GSK-3β is an enzyme that normally marks β-catenin for degradation.
When GSK-3β is active, β-catenin levels drop and Wnt signaling shuts down.
KY19382 partially inhibits GSK-3β, which leads to:

Less β-catenin degradation
Higher β-catenin accumulation in the nucleus
Activation of Wnt-responsive genes

This increases:
cell proliferation
tissue regeneration
hair follicle growth activity

The Difference Between KY19382 & Minoxidil

The main differences between KY19382 Powder and Minoxidil lie in their mechanisms of action, research stages, and depth of action. It is a small molecule compound at the forefront of regenerative medicine. It strongly activates the Wnt/β-catenin signaling pathway by simultaneously inhibiting CXXC5-Dvl binding and GSK-3β activity. This pathway is a key hub for hair follicle stem cells, skin regeneration, and tissue repair. Therefore, it has demonstrated the ability to promote hair follicle regeneration, accelerate hair growth, and even induce the formation of new hair follicles in animal and cell studies.

In contrast, Minoxidil is an anti-hair loss drug that has been widely used globally for decades. By activating K-ATP potassium ion channels, minoxidil dilates blood vessels, boosting the blood supply surrounding hair follicles. This prolongs the anagen phase of hair follicles and encourages more aggressive growth of already-existing hair follicles. Minoxidil does not stimulate the growth of new hair follicles or take part in stem cell-level regeneration processes. However, its safety, dosage range, and side effect assessments are relatively well-defined, and there is mature clinical evidence for its use in the treatment of androgenetic alopecia. Therefore, the fundamental difference between the two is that KY19382 is a "regenerative, experimental" compound that mainly activates stem cells and regenerative pathways; while Minoxidil is a "blood flow improvement, clinically mature" hair loss treatment that mainly maintains and strengthens the growth of existing hair follicles.

Are There Any Side Effects Of KY19382

Rather than documented adverse responses, the following content relates to possible dangers of KY19382 API based on its Wnt/β-catenin activation capabilities and experimental data.

1. Potential Risk of Excessive Cell Proliferation

Theoretically, long-term or excessive activation of the Wnt pathway may lead to abnormal cell proliferation, thereby increasing tissue overgrowth, local thickening, and even potentially enhancing the risk of tumor formation in the long term. This risk is currently only theoretical.

2. Potential Skin Tissue Reactions

In animal skin studies, KY19382 promoted tissue regeneration and cell migration, sometimes leading to localized skin thickening, increased keratinization, and abnormally elevated cell activity. These phenomena are byproducts of its strong stimulating effect on regeneration and are not necessarily harmful in themselves, but they indicate that it may have a strong biostimulatory effect on skin tissue.

3. Potential Risk of Inflammatory or Immune Responses

Any signaling pathway modulator with strong biological activity may trigger local inflammation or immune system involvement.

4. Potential Tissue Regeneration Imbalance

In animal studies, KY19382 has been shown to speed up wound healing and stimulate the growth of new hair follicles. Nevertheless, an imbalance in the tissue regeneration process, such as local over-regeneration, aberrant tissue structure development, or aberrant cell differentiation direction, may also result from overly potent stem cell activation.

Factory

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

Certificate

Package

Logistics Update

In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

Company's Profile

Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry if you need KY19382 API.

And if you want to know the KY19382 Powder price, please contact XI'an Sonwu.

Email: sales@sonwu.com

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