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Fevipiprant Powder

Fevipiprant Powder

Appearance: White Powder
Specification: 99%HPLC
CAS: 872365-14-5
Molecular Formula:C19H17F3N2O4S
Molecular Weight:426.41
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package, Capsules)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of fevipiprant powder in China. We warmly welcome yuo to wholesale bulk fevipiprant powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Fevipiprant

Fevipiprant Powder, also known as NVP-QAW039 or QAW039 powder, is an orally active and effective CRTh2 receptor antagonist, which can be used for oral treatment of asthma, and has successfully targeted severe eosinophilic asthma. QAW039 is also an effective inhibitor of pgd2-induced cytokine release from human Th2 cells.

At present, it has been proved that this drug has relatively stable security.QAW039 is a new oral prostaglandin D2 receptor 2 (DP2; known as CRTh2) antagonist, which is still under development and is mainly used to treat severe asthma and atopic dermatitis.Nowadays, as the medical community continues to invest in further research into the drug, more and more suppliers are producing it. Xi 'an Songwu has also become one of them. If you are interested in this raw material, please contact us online.

 

Fevipiprant molecular formula

 

Certificate of Analysis

Analysis

Specification

Result

Apperance

White powder

Complies

Assay

98.0%~102.1%

99.5%

Residue On Ignition

≤0.1%

0.05%

Particle Szie

100% through 80 mesh

80 mesh

Loss on drying

≤1%

0.26%

Extract Solvent

Water&Ethanol

Complies

Heavy metal

Cadmium(Cd)

≤0.2ppm

0.10ppm

Lead(Pb)

≤0.2ppm

0.05ppm

Arsenic(As)

≤0.6ppm

Complies

Mercury(Hg)

≤0.25ppm

Complies

Total bacteria count

≤1000cfu/g

102cfu/g

Fungi

≤100cfu/g

33cfu/g

Samonella

Negative

Complies

E. Coli

Negative

Complies

Conclusion

This product complies to international standards

 

 Where To Buy QAW039 Powder

Xi'an Sonwu Biotech Co.ltd. has rich experience in the global trade and health industry. Our company's principle is based on faith and quality first. We strictly manage product quality, which means starting from raw materials. In addition, We deal with all the details and minimize the cost, so our customers can get affordable products. Based on these, customers have given a lot of good feedback on our products. So when purchasing QAW039, please look for Xi'an Sonwu Biotech Co. ltd.

 

Xi'an Sonwu completely makes sure product’s quality, so sample can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum of Quantity

Powder

5g

10g

Bulk Capsules

200 capsules

200 capsules

Bottled Capsules

5 bottles

5 bottles

 

Customers’ Good Comment

 

Fevipiprant comment

 

OEM Service

Xi'an Sonwu not only can supply pure Fevipiprant Powder but supply its capsules as well.

So any customers could customize capsules they like. And items below can be supplied.

1.Customized capsules shells (size, color, material)

2.Customized bottles(size, color, material, style)

3.Customized packaging(vacuum foil packaging, box, drum)

4.Customized label(paint film, matte film, optical mask)

 

Fevipiprant OEM

 

How Does Fevipiprant Work

The results of the second phase of clinical trials in 2019, cellular work, and computational modeling show why the first drug to treat asthma in 20 years can help reduce asthma attacks.Researchers from Leicester in the UK and Vancouver in Canada have shown that the drug QAW039, an oral selective prostaglandin D2 receptor antagonist, can reduce the number of smooth muscles in the lining of the respiratory tract.The findings are published in the journal Science Translational Medicine.

 

Professor Chris Bryling, a consultant in respiratory medicine at Leicester Hospital and a professor of respiratory medicine at the University of Leicester, has shown for the first time that QAW039 can not only reduce respiratory inflammation but also reduce the number of muscles in the lining of the respiratory tract.This may explain some of the effects seen in post-treatment symptoms and respiratory tests.The increase of airway smooth muscle is the strongest predictor of the decrease of airflow into the lungs due to airway stenosis.It dramatically increases the likelihood of more frequent asthma attacks and even asthma-related deaths.The Leicester Biomedical Research Center of the National Institutes of Health (NIHR) supported the study.Professor Brightling, a senior researcher at NIHR, also said that previous trials have found that QAW039 can improve symptoms, respiratory tests, and inflammation and help repair patients' respiratory lining.

 

Currently, no routinely-available drug on the NHS targets smooth muscle mass to reduce asthma symptoms. For people with severe asthma, a procedure called thermoplasty, which uses thermal energy to decrease the amount of smooth muscle in the airways, may be offered. This requires sedation in the hospital and is not a cure nor suitable for everyone. Most patients with severe asthma rely on high-dose inhaled or oral steroids to manage their symptoms. Its potential to reduce the need for patients to take oral steroids either continuously or for attacks could be seen as a positive step, given the range of possible side effects associated with steroids. These include weight gain, osteoporosis, diabetes, and high blood pressure. The more patients take steroids to manage their asthma symptoms, the less effective the same doses will become.

 

 

fevipiprant mechanism of action

 

What Are The Side Effects of Fevipiprant

A Phase I study evaluated the pharmacokinetics and safety of a range of doses of QAW039 powder given as single and multiple doses in 48 healthy volunteers.26 Peak concentrations of QAW039 were observed 1–3 hours after dosing with a half-life of approximately 18–20 hours. This drug was well tolerated, and the adverse events were similar between QAW039 and placebo. There were no significant adverse events or death, and the most common side effects were headache and nasal congestion.

 

Factory Environment

Xi'an Sonwu production factory is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers insist on developing new products. The following is the testing environment of our laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for our products and providing our customers with a quality experience.

 

factory a

factory b

 

Certifications

 

Fevipiprant certificates

 

Packaging

 

Fevipiprant packaging

 

Logistics

 

Fevipiprant logistics

 

 In addition to guaranteeing the product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi’an Sonwu supply all kinds of couriers according to different needs.

 

courier

 

Why Choose Us

1.Our company has been engaged in import-export for over 10 years and has rich experience in import and export industry.

2.Our company has 10-year experience in product development, production and sales.

3.Our company has a professional team with clear division of labor.

4.We have professional laboratories and equipment to ensure high quality products.

5.Products are tested by third parties.

6.We provide OEM service.

 

If you want to know the Fevipiprant Powder price,don't hesitate to get in touch with us at:

Email:sales@sonwu.com

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