Best Diosmin Supplement
Diosmin powder is a flavonoid compound belonging to the flavonol class with a molecular formula of C28H32O15. It is mainly made of hesperidin, which is extracted from natural plants as raw materials. It primarily exists in the peels of citrus fruits such as oranges and grapefruits and is semi-synthetic. It has a vitamin P-like effect, can reduce vascular fragility and abnormal permeability, and is also used as an auxiliary treatment for hypertension and arteriosclerosis. It is more effective than rutin and hesperidin hesperidin in treating capillary fragility and has low toxicity. It is a drug that enhances venous tension and a vascular protector. For the venous system, it can prolong the contraction time caused by the action of adrenaline on the venous wall, thereby enhancing venous tension; for the microcirculatory system, it can reduce the permeability of capillaries and improve their resistance; for the lymphatic system, it can increase the lymphatic drainage speed and the contraction of lymphatic vessels, improve lymphatic return, and reduce edema. In short, it is an effective drug for treating venous system diseases and is widely used in clinical practice. Xi'an Sonwu can offer you powder and diosmin capsules; feel free to text Xi'an Sonwu if needed.
Certificate Of Analysis
Items |
Specification |
Results |
Appearance |
Greyish-yello or light yellow hygroscopic powder, practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in ethanol(96 %).It dissolves in dilute solutions of alkali hydroxides. |
Conforms |
Identification |
The infrared absorption spectrophotometry of the product is same as the infrared absorption spectrophotometry of diosmin CRS. |
Conforms |
Examine the chromatogram obtained in the assay. The principal peak in the chromatogram obtained with the test solution(a) is similar in retention time and size to the principal peak in the chromatogram obtained with the reference solution(a). |
Conforms |
|
Iodine |
≤0.1% |
Conforms |
Pyridine |
≤200ppm |
134ppm |
Particle size |
90% pass 80 mesh |
Conforms |
Heavy metals |
≤20ppm |
Conforms |
Related substance |
Impurity A ≤ 0.5% |
0.05% |
Impurity B ≤ 4.0% |
0.53% |
|
Impurity C ≤ 3.0% |
2.42% |
|
Impurity D ≤ 0.6% |
0.01% |
|
Impurity E ≤ 3.0% |
1.80% |
|
Any unspecified impurity ≤ 0.4% |
0.36% |
|
Total Bacteria |
1,000cfu/g Max |
<10cfu/g |
Yeast & Mold |
100cfu/g Max |
<10cfu/g |
Coliform |
Negative in 1g |
Negative |
Assay |
94.0~102.0% |
96.6% |
Where To Buy Diosmin
Xi'an Sonwu Biotech Co. Ltd. has more than ten years of industry experience, specializing in producing and selling raw materials. Xi'an Sonwu has established solid and reliable partnerships with countries in America, Asia, Europe, and Oceania. Xi'an Sonwu puts product quality first and strives to provide every customer with high-quality services to meet their needs fully.
High-quality products are Xi'an Sonwu's top priority, and the company's dedication to perfection is seen in all aspects of its operations, including the selection of raw materials, manufacturing processes, sample testing, and staff professionalism. By meticulously managing every detail, Xi'an Sonwu can minimize costs without compromising quality, ensuring customers receive products of exceptional value.
Xi'an Sonwu is proud of the positive feedback it has received from customers, who have consistently recognized the quality of the products. To further prove product confidence, Xi'an Sonwu will provide samples for you to test.
Form |
Sample Amount |
MOQ |
Powder |
1kg |
1kg |
Bulk capsules |
1000 capsule |
1000 capsule |
Bottle capsules |
10 bottle |
10 bottle |
Customers' Good Comment
OEM Service
Xi'an Sonwu can supply powder and capsules.
So customers can customize the capsules they want. The things listed below are available.
1. Customized capsules shells (size, color, material)
2. Customized bottles(size, color, material, style)
3. Customized packaging(vacuum foil packaging, box, drum)
4. Customized label(paint film, matte film, optical mask)
What Is Diosmin Good For
1. Varicose veins of the lower limbs
Varicose veins of the lower limbs are caused by weak venous walls or insufficiency of venous valves, which lead to venous dilatation, tortuosity, and congestion. This condition usually causes heaviness, pain, swelling, and visual prominence of the veins in the legs. It can reduce leg edema, discomfort, and heaviness from varicose veins in the lower limbs. Relieves pain by enhancing the tension of the venous walls and improving blood return. Long-term use can reduce the degree of venous dilatation and the incidence and severity of varicose veins. In addition, it can also help prevent complications of varicose veins in the lower limbs, such as phlebitis, venous thrombosis, and venous ulcers.
2. Acute or chronic hemorrhoids
Clinical studies have shown that for patients with chronic hemorrhoids, it can effectively improve the size of their hemorrhoids, reduce the number of bleeding and anal prolapse, and effectively prevent and treat their acute attacks; secondly, for patients with acute hemorrhoid attacks, the use of it based on symptomatic treatment such as hemostasis can quickly control bleeding and relieve perianal pain, thereby effectively relieving patients' pain and improving prognosis.
3. Lymphatic reflux disorder, lymphedema
Lymphatic reflux disorder refers to the impaired function of the lymphatic system, which leads to the inability of lymphatic fluid to be effectively discharged, thereby causing fluid accumulation and swelling. Common lymphatic reflux disorders include primary and secondary lymphedema. It can effectively improve lymphatic reflux and reduce limb swelling. Clinical studies have shown that after taking it, patients with lymphedema have significantly reduced swelling and pain in their limbs, making lymphatic circulation smoother and improving their quality of life and physical health.
4. Peripheral skin ulcers
Peripheral skin ulcers are chronic skin injuries that usually occur on the inner side of the calf and ankle, mainly caused by venous insufficiency. Venous hypertension, which accumulates blood and fluid in the lower limbs, damages the skin, and causes ulcers, is the outcome of venous insufficiency. Clinical studies have shown that based on promoting skin healing treatment, the use of it can effectively accelerate the prognosis of skin wounds or ulcers, reduce local inflammatory reactions, relieve skin pain, and effectively improve the prognosis of the disease.
Diosmin Mechanism Of Action
Diosmin powder is widely used to treat diseases related to the venous and lymphatic systems, such as chronic venous insufficiency, hemorrhoids, and lymphedema. Its mechanism of action involves multiple biological mechanisms and targets, and it mainly exerts its therapeutic effects by improving vascular function, reducing inflammation, and promoting blood and lymphatic circulation.
1. Enhancement of venous tone
It improves venous function by increasing the tension of the venous wall. This effect is mainly achieved by contracting venous smooth muscle cells, reducing venous dilation, and thus reducing the pressure in the vein. It can relieve symptoms caused by venous hypertension, such as leg swelling and discomfort.
2. Anti-inflammatory effect
It has significant anti-inflammatory properties. It lessens the inflammatory response by preventing the synthesis of inflammatory mediators like prostaglandins and cytokines (including IL-6 and TNF-α). In addition, it reduces the adhesion of leukocytes to endothelial cells, further reducing local inflammation and swelling.
3. Antioxidant effect
It has antioxidant properties and can neutralize the body's free radicals and reactive oxygen species (ROS). This antioxidant effect protects vascular endothelial cells from oxidative damage, thereby maintaining the health and function of blood vessels.
4. Improve microcirculation
It relieves the symptoms of venous insufficiency by improving microcirculation. It helps improve local blood supply by enhancing blood flow in microvessels and capillaries, reducing blood congestion, and accelerating tissue repair and ulcer healing.
5. Improve lymphatic function
It helps enhance the function of the lymphatic system and promotes the excretion of lymph fluid. It reduces the swelling and discomfort caused by lymphedema by strengthening the lymphatic vessel walls' function and reducing the lymph fluid's leakage.
6. Reduce capillary permeability
It reduces fluid leakage, swelling, and edema by reducing capillary permeability. This effect helps relieve symptoms caused by venous insufficiency and lymphedema.
Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture, and store the products, so have adequate stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.
Certificates
Packaging
Logistics
Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
FAQ
Clinical Application and Dosage
Chronic venous insufficiency
It helps relieve leg swelling, pain, and heaviness. 500 mg twice daily is usually recommended.
Hemorrhoids
It is used for the relief of pain, bleeding, and swelling of hemorrhoids. For acute hemorrhoids, 1000 mg twice daily is recommended (for the first four days), then the dose is adjusted to 500 mg twice daily.
Lymphedema
It is done by lessening edema and enhancing lymphatic drainage. A 500 mg twice-daily dose is advised for the best outcomes for several months.
If you want to know the diosmin price, you can contact Xi'an Sonwu. Click the email, and then you get high-quality diosmin powder.
Email: sales@sonwu.com
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