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Bempedoic Acid Powder

Bempedoic Acid Powder

Appearance: White Powder
Specification: 98%
CAS: 738606-46-7
Molecular Formula: C19H36O5
Molecular Weight: 344.49
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of bempedoic acid powder in China. We warmly welcome yuo to wholesale bulk bempedoic acid powder for sale here from our factory. Quality products and reasonable price are available.

 

What Kind Of Drug Is Bempedoic Acid

Bempedoic acid powder is a well-defined small-molecule fatty acid derivative with the molecular formula C₂₁H₃₆O₅ and a molecular weight of approximately 368.5. Its chemical structure can be considered a substituted long-chain dicarboxylic acid analog, containing a hydrophobic carbon chain backbone and multiple polar functional groups, including carboxyl and hydroxyl groups. This combination of a hydrophobic chain and polar end groups confers good biocompatibility and membrane permeability. From a structural design perspective, beempedoic acid is not a traditional direct-acting inhibitor but rather a prodrug. It requires specific enzyme catalysis to be converted into its active form in vivo before it can exert its effect. Its molecular backbone contains substituents at specific positions and a specific stereoconfiguration, enabling it to be recognized and converted by specific enzymes in the liver, thereby achieving tissue-selective activation. In terms of physicochemical properties, beempedoic acid typically appears as a white or off-white crystalline powder, is chemically stable, and is not easily degraded under normal storage conditions. It exhibits good solubility in organic solvents but limited solubility in water; however, better dispersibility can be achieved through salt formation or formulation optimization. The carboxyl group in the molecule confers it some ionization ability, which helps it form a stable form in the physiological environment. As a structurally optimized metabolic regulatory molecule, Bempedoic Acid embodies the design philosophy of achieving a balance between targeted activation and safety through structural modification at the medicinal chemistry level, providing an important reference for the development of lipid metabolism regulatory compounds.

As one of the most popular products, this powder has received many good comments and feedback from customers. What mostly attracts customers is high quality. In addition, Xi'an Sonwu offers highly competitive prices. If you want to learn more, just contact Xi'an Sonwu Biotech Co., Ltd.

product-453-182

 

Certificate Of Analysis

Items

Standards

Results

Appearance

Off-White Powder

Conform

Odor

Characteristic

Conform

Assay

≥98.0%

98.57%

Particle Size

100% pass 80mesh

Conform

Moisture

<5.0%

Conform

Ash Content

<4.0%

Conform

Solvent Residue

Eur.Pharm

Conform

Total Heavy Metals

<10 ppm

Conform

Arsenic

<1.0 ppm

Conform

Lead

<1.0 ppm

Conform

Mercury

<0.5 ppm

Conform

DDT

<0.2ppm

Conform

E. Coli

Negative

Negative

GMO Status

Complies

GMO Free

Irradiation

Complies

Irradiation Free

 

Is Bempedoic Acid Over The Counter

Xi'an Sonwu Biotech Co., Ltd. has rich experience in the global trade and the health industry. Insisting on faith-based, quality-first principles is Xi'an Sonwu's principle. Xi'an Sonwu strictly controlscontrols product quality, which means selection starts with the raw materials. Besides, Xi'an Sonwu handles every detail and reduces costs to the maximum extent so that the customers can get cost-effective products. Based on these, customers have given much good feedback to the products. So look for Xi'an Sonwu Biotech Co., Ltd. when buying it.

 

Xi'an Sonwu ultimately makes sure of the product's quality so the samples can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum Of Quantity

Powder

10g

10g

 

Customers' Good Comment

Customers Good Comment

 

Is Bempedoic Acid Better Than Statins

Bempedoic acid powder is primarily used to explore its role in lipid metabolism regulation and cholesterol level management. With the deepening research into metabolic diseases and cardiovascular risk factors, regulating cholesterol synthesis pathways has become an important research direction. Bempedoic acid has shown the potential to reduce cholesterol production-related indicators in vivo in various studies, particularly in the regulation of low-density lipoprotein cholesterol (LDL-C), attracting widespread attention. Unlike traditional methods relying on exogenous interventions, this compound mainly exerts its effects by regulating endogenous metabolic pathways, thus possessing high value in metabolic regulation research. Furthermore, beempedoic acid has been observed to complement other lipid regulation strategies in studies, providing more possible pathways for comprehensive metabolic management. Because its effects are mainly concentrated in key metabolic tissues such as the liver and not widely distributed in muscle tissue, it exhibits good tissue selectivity in studies. This characteristic makes it considered one of the molecules with potential advantages in metabolic health-related research. Overall, beempedoic acid demonstrates a stable and predictable biological mode of action in lipid metabolism, cholesterol regulation, and related metabolic homeostasis studies.

anemia effect

 

From a mechanistic perspective, the core characteristic of beempedoic acid lies in its role as a "liver-specifically activated precursor molecule," achieving its biological effects by regulating key enzymes in the cholesterol synthesis pathway. After entering the body, this compound is first converted into its active form, beempedoic acid-CoA, in the liver by specific enzymes (such as long-chain acyl-CoA synthase). This active metabolite inhibits ATP citrate lyase (ACL), an enzyme located upstream of the cholesterol and fatty acid biosynthesis pathway and a crucial link between glucose metabolism and lipid synthesis. By inhibiting ACL activity, beempedoic acid reduces the production of acetyl-CoA, thereby decreasing the substrate supply for cholesterol and fatty acid synthesis, ultimately leading to a decrease in intracellular cholesterol levels. With the reduction of intracellular cholesterol in hepatocytes, the expression of low-density lipoprotein receptors (LDL receptors) on the cell surface is upregulated, thereby promoting the clearance of LDL from the blood. This mechanism is of significant importance in metabolic regulation. Furthermore, because this compound is primarily activated in the liver, and the corresponding activating enzyme is lacking in skeletal muscle, its action exhibits significant tissue selectivity. This characteristic explains its differentiated biological performance at the mechanistic level. By regulating the lipid synthesis pathway upstream, Bempedoic Acid constructs a relatively mild and systemic metabolic regulatory mechanism.

hypertension

 

Bempedoic Acid represents an innovative small molecule that optimizes lipid homeostasis through upstream metabolic regulation. Its research value lies not only in cholesterol level regulation but also in its unique pathway of action and tissue selectivity. As modern biomedical research gradually shifts from single-target intervention to multi-level metabolic network regulation, molecules like Bempedoic Acid, which can function at key nodes in metabolic pathways, are becoming important research subjects. Inhibiting the key enzyme ACL reduces the supply of lipid synthesis substrates at the source, providing a new approach to lipid metabolism regulation that differs from traditional strategies. In metabolic health and cardiovascular research, Bempedoic Acid is used to explore how to effectively manage cholesterol levels while maintaining overall metabolic stability. Its liver-specific activation characteristics give it good tissue selectivity in studies, providing a theoretical basis for reducing the impact of non-target tissues. Furthermore, this compound can serve as an important tool molecule for studying lipid metabolism pathways, helping to elucidate the regulatory mechanisms of ACL-related pathways under different metabolic states. In terms of active pharmaceutical ingredients and scientific research applications, Bempedoic Acid possesses advantages such as a well-defined structure, good stability, and a clear mechanism of action, making it suitable for various applications, including cell experiments, animal models, and metabolic pathway research. Simultaneously, its molecular structure provides a solid foundation for further derivative design and structural optimization. With the continuous advancement of research on metabolic diseases, Bempedoic Acid is expected to continue to play a valuable role in lipid metabolism regulation, energy metabolism research, and the development of related functional products, becoming one of the representative high-potential raw materials in the field of metabolic research.

Cardiovascular

 

Factory Environment

Xi'an Sonwu production factory is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers insist on developing new products. The following is the testing environment of the laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for the products and providing the customers with a quality experience.

factory

 

Certificates

certificates

 

Packaging

packaging

 

Logistics Record

Logistics Record

In addition to guaranteeing product quality, the other most vital thing is that clients can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

FAQ

1. How do you contact Xi'an Sonwu Biotech Co., Ltd.?

You can contact me by email, telephone, or social media.

2. How do you ensure the quality of the product?

Xi'an Sonwu tests each batch so Xi'an Sonwu can supply the COA for customers. Besides, the products pass the tests for HPLC, UV, GC, TLC, etc. Xi'an Sonwu also cooperates with third parties, like SGS.

3. How to pack and store?

Pack: Vacuum-sealed foil packaging & Sealed export-grade drum or pack according to customers' needs.

Storage: Keep it in a dry and cool place, and avoid strong light and heat.

 

If you want to buy bempedoic acid powder, feel free to contact Xi'an Sonwu.

E-mail: sales@sonwu.com

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