99% Ibrutinib Powder

Ibrutinib Mechanism Of Action

99% Ibrutinib powder is a small molecule inhibitor that targets Bruton's tyrosine kinase (BTK), which plays a crucial role in the B-cell receptor signaling pathway.

Ibrutinib works by irreversibly binding to the active site of BTK, thereby inhibiting its activity. When BTK is activated, it phosphorylates downstream targets such as phospholipase C gamma (PLCγ2), which results in the activation of downstream signaling pathways including NF-κB, MAPK/ERK and PI3K/AKT. These pathways play a critical role in the survival and proliferation of B-cells.

By inhibiting BTK, ibrutinib prevents the phosphorylation and activation of downstream targets, which disrupts the signaling pathways that support the survival and proliferation of malignant B-cells. This results in the inhibition of cell proliferation, induction of apoptosis (programmed cell death).

Ibrutinib is a highly selective inhibitor of BTK, with little activity against other kinases. This selectivity is important because it minimizes off-target effects and reduces the potential for toxicity.

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Where To Buy Powder Ibrutinib

Xi'an Sonwu has rich experience in the global trade and health industry. Credit-based and quality first is the principle of Xi'an Sonwu company. Xi'an Sonwu strictly controls product quality, so the selection starts with raw materials. In addition, we handle every detail and minimize costs so that our customers can get the most cost-effective products. Based on these, customers have given high praise to our products. So find Xi'an Sonwu BiotechCo., Ltd if you need 99% Ibrutinib powder.

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Is Ibrutinib Water Soluble

Yes, ibrutinib is water-soluble. It is classified as a hydrophilic compound, meaning that it has a high affinity for water molecules and can dissolve in water-based substances.

Ibrutinib is an oral medication that is used in the treatment of certain types of disease, including mantle cell lymphoma, chronic lymphocytic leukemia (CLL), and Waldenstrom's macroglobulinemia. It is a small molecule inhibitor of Bruton's tyrosine kinase (BTK), which is an enzyme that is involved in the signaling pathways of B cells, a type of immune cell. By inhibiting this enzyme, ibrutinib can prevent the abnormal growth and proliferation cells.

The water solubility of ibrutinib plays an important role in its pharmacokinetics, or how it is absorbed, distributed, metabolized and eliminated in the body. When ibrutinib is taken orally, it is quickly absorbed into the bloodstream, and its solubility in water helps it to be distributed throughout the body, where it can reach its target cells. Additionally, because it is hydrophilic, it can be easily excreted from the body through the kidneys.

What Are Side Effects Of Ibrutinib

Ibrutinib has been shown to be highly effective in some conditions, there are also potential side effects that individuals should be aware of.

Some of the most common side effects of ibrutinib include:

1. Diarrhea: This can be one of the first side effects to develop and can be mild to severe in intensity. Patients may need to adjust their diet and take over-the-counter remedies to manage symptoms.

2. Nausea and vomiting: These may also occur early on and can be managed with medications prescribed by a doctor.

3. Fatigue: This is a common side effect and can persist despite treatment.

4. Decreased appetite and weight loss: This can result from feeling nauseous or having diarrhea.

5. Bruising and bleeding: Ibrutinib can affect the ability of the blood to clot properly, leading to bruising and bleeding.

6. Increased risk of infection: Ibrutinib can reduce the number of white blood cells, which help fight infections.

7. Rash: Some patients may develop a rash, which can range from mild to moderate in severity.

Less common, but potentially more serious side effects include:

1. Heart rhythm problems: Ibrutinib has been associated with atrial fibrillation and other heart rhythm problems.

2. High blood pressure: This can develop while on the medication, and patients should have their blood pressure regularly monitored.

3. Blood clots: Ibrutinib can increase the risk of blood clots in some patients.

What Happens When Ibrutinib Stops Working

Ibrutinib works by inhibiting B-cell receptor signaling and preventing the cancer cells from growing and dividing.

However, like all treatments, ibrutinib may stop working after some time, and the bad cells can start to grow and spread again. There are several reasons why ibrutinib may stop working:

1. Resistance: The bad cells may develop resistance to ibrutinib over time, making the drug less effective. This can happen because the bad cells mutate or change in some way that makes them less sensitive to the drug.

2. Disease progression: If the disease has already advanced significantly before starting treatment, ibrutinib may not be effective at stopping the bad cells from growing and spreading.

3. Side effects: Some patients may experience side effects from ibrutinib that are severe enough to require them to stop taking the drug. This can lead to the disease coming back.

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1.Xi'an Sonwu Biotech Co.,Ltd has its own factory,so it has adequate stock. Also,Xi'an Sonwu has clean and tidy producing department with advanced equipment. With the lead of Xi'an Sonwu, researchers are constantly developing new products to meet customer's need.

2.Xi'an Sonwu Biotech Co.,Ltd has advanced test equipment and professional testers, which all show that Xi'an Sonwu aims to supply accurate and effective data and good service.

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Except guarantee the product’s, the other most important thing is customers could receive the goods smoothly. So, Xi’an Sonwu supply all kinds of courier according to different need.

Company's Profile

Xi’an Sonwu Biotech Co . Itd is a professional Chinese manufacturer and products supplier. It was founded in 2012, and located in Hi-Tech industrial Zone Xi’an city, Shannxi province, China. It pays all attention on development, research and production of food additives, plant extract , APl and other ingredients of health care products. Our company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, Plant Extract. We sincerely believe that the premise of a great cooperation is best services and good quality. So, welcome your inquiry.

If you want to buy 99% ibrutinib powder, feel free to contact Xi'an Sonwu.

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