Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of way 316606 powder in China. We warmly welcome yuo to wholesale bulk way 316606 powder for sale here from our factory. Quality products and reasonable price are available.
Description
Way 316606 powder is derived from way-316606, which is used in the treatment of osteoporosis---a condition that causes fragile bones and increases susceptibility to fractures. Way 316606 is a SFRP1 inhibitor, which means that it prevents the protein SFRP1 from being produced and activated. Now it is widely used in the treatment of male pattern baldness.
As a professional manufacturer and supplier in China, Xi'an Sonwu has its own factory with advanced equipment and professional researchers, which all ensure the sufficient stock and high quality. Xi'an Sonwu has always put product quality and customer needs in the first place, which win praise from many regular customers, and these have also promoted Xi'an Sonwu to continue to make progress in a virtuous circle. If you're interested in the way 316606, please contact with Xi'an Sonwu.
Specification
ANALYSIS | SPECIFICATION | RUSULT |
Appearance | Almost White or White Powder | Conforms |
Solubility | Soluble freely in ethanol, acetone, dichloromethane, methanol, ethyl ethanoate, soluble slightly in isopropyl ether, almost insoluble in water and petroleum ether. | Conforms |
Melting Point | 100~106℃ | 102.5~104.5℃ |
Loss on Drying | ≤0.1% | 0.055% |
Heavy Metals | ≤20ppm | Conforms |
Chromatographic Purity | ||
Single Impurity | ≤1.0% | 0.32% |
Total Impurities | ≤1.0% | 0.78% |
Residue Solvents | Ethanol≤0.2% Isopropyl Ether≤0.15% Dichloromethane≤0.05% | Conforms |
Assay (HPLC) | ≥99.0% | 99.36% |
Conclusion | Conforming to Enterprise Standard | |
Science Principle & How does it work?
Hair loss is a common disorder and can lead to psychological distress. Androgenic alopecia (AGA), also called male-pattern baldness, is the most common form of hair loss. Therefore, more effective human hair growth–modulatory agents urgently need to be developed. Way 316606 is just such a product.
Way 316606 powder was originally developed as a drug to treat osteoporosis. But then doctors and researchers found that it works and can cure baldness and help to regrow hair loss. Thus way-316606 hair loss drug is available in market.
The protein SFRP1 works as a modulator of the Wnt signaling pathways. These pathways-and more specifically the 'canonical' pathway---lead to the regulation of gene transcription, which is crucial when determining what role genes will play.
Interestingly, the Wnt signaling pathway has been identified as playing a part in the development of osteoporosis. This occurs as the pathway encourages the development of more bone-resorbing cells (osteoclasts) than bone-forming cells (osteoblasts).
It works, then, by triggering the Wnt signaling pathway. This helps the two different cell types to be better differentiated, leading to less bone degradation and further bone growth.
But what does this have to do with hair loss?
While wnt signaling pathways also play a role in hair loss.
As hair follicles and their accompanying hairs develop, a process known as cell differentiation takes place. This occurs in the Dermal Papilla (DP), which is essentially the base of the follicle.
During this process, proteins are produced and delivered to various parts of the follicle. However, over-expression of certain protein-particularly SFRP1-can lead to quickened cycling and structural defects of the hair strand. If left uninterrupted, this can lead to follicle miniaturization. This all takes place as part of the Wnt signaling pathway, and is much more common in individuals with hair loss disorders.
SFRP1 is a member of the SFRP family that act as soluble modulators of Wnt signaling. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity).
Studies have suggested that SFRP1 functions as an inhibitor of canonical Wnt signaling and inhibits the development and growth of many tissues such as hair follicles.
As way regulates the Wnt signalling pathway, it's believed that it can play a role in slowing down protein over-expression and result in regular hair growth and development. Therefore, inhibiting SFRP1 through the compound way 316606 could be an approach to facilitate Wnt signaling and promote hair growth. This approach would have applications for treating human hair loss diseases such as MAA.
Certifications
Factory
Shipping & Packaging
Xi'an Sonwu supplier is a professional manufacturer with its own factory. The clean and tidy production workshop with advanced equipment provides customers with safe and healthy products. The company focuses on the development, research and production of food additives, plant extract, API and other raw ingredients of health care products. If you're interested and want to buy Way 316606 Powder, please contact with Xi'an Sonwu Biotech Co., Ltd.
Email ID: sales@sonwu.com
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