Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of cb-03-01 (breezula) in China. We warmly welcome yuo to wholesale bulk cb-03-01 (breezula) for sale here from our factory. Quality products and reasonable price are available.
Introduction
CB-03-01 (Breezula) is a topical androgen receptor inhibitor initially developed mainly for the treatment of acne vulgaris. Now scholars are also studying its effect on male hair loss. It has been found that it can inhibit the androgen receptor regulatory pathway. CB-03-01, also known as clascoterone, was commercialized initially under the name Breezula. CB-03-01 is considered to compete with DHT for binding androgen receptors in sebaceous glands and dermal papilla cells in hair follicles.
To study its anti-alopecia effect, researchers recruited more than 400 participants aged 18 to 55 years with mild to moderate male alopecia in Germany to evaluate the efficacy and safety of four different administration regimens and excipients for CB-03-01. All participants were randomly assigned to apply CB-03-01 or excipient to the bald area of the scalp every day for 12 months. Five treatment groups were analyzed-2.5% solution, twice a day, 5% solution, twice a day, 7.5% solution, twice a day, 7.5% solution, once a day, carrier solution, twice a day.
After the research, cb-03-01 hair loss has been the hots words. Researchers concluded that it has great anti hair loss effect. As a CB-03-01 manufacturer, Xi'an Sonwu Biotech Co., Ltd. promises to supply top purity raw material. If you are interested in CB0301, feel free contact Xi’an Sonwu.
Certificate of Analysis
ANALYSIS | SPECIFICATION | RUSULT |
Appearance | White Crystalline Powder | Conforms |
Identification | HNMR | Conforms |
LCMS | Conforms | |
Impurity | ≤0.4% | Conforms |
Ignition Residue | ≤0.1% | Conforms |
Any Single Impurity | ≤0.65% | ≤0.5% |
Total Impurities | ≤2.0% | ≤1.0% |
Granularity D90 | ≤110µm | ≤100µm (160 mesh) |
Assay(HPLC) | ≥99% | 99.75% |
Conclusion | Conforming to Enterprise Standard | |
HPLC Test
About us
Xi'an Sonwu Biotech Co., Ltd. has rich experience in global trade and health industry. Insisting on faith-based and quality first is our Xi'an Sonwu’s principle. Xi'an Sonwu strictly controls product quality, which means selection starts from raw material. Besides, Xi'an Sonwu handles every detail and reduce cost to the maximum extent, then our customers can get cost-effective product. Based on these, customers have given much good feedback to our products. So enquire Xi'an Sonwu Biotech Co., Ltd. when you need to buy CB-03-01 (Breezula). What’s more, Xi'an Sonwu supplies powder dissolving formula as well.
Xi'an Sonwu completely makes sure product’s quality, so sample can be supplied. Here is the quantity.
Form | Sample Amount | The Minimum of Quantity |
Powder | 5g | 10g |
Customers’s Good Comment
CB-03-01 VS. RU58841
RU58841 is a non-steroidal anti-androgen initially developed for the treatment of facial acne and androgenic alopecia, also known as male alopecia. RU58841 binds to androgen receptors and directly inhibits naturally occurring testosterone and dihydrotestosterone (DHT). This can lead to an overall anti-androgen effect in the body. American researchers studied the effects of RU58841 on rhesus monkeys. They found that topical application of the product significantly increased hair density, thickness and even length in rhesus monkeys with male alopecia. In fact, Japanese researchers have observed that RU58841 is more effective than finasteride in in the treatment of male hair loss and has the additional advantage of not causing any systemic side effects.
CB-03-01 VS. Finasteride
Finasteride is a commonly used 5 α-reductase inhibitor, which can increase hair's number and personal appearance. It has been found that CB-03-01 has the same effect as finasteride. A 2019 study found that CB-03-01 inhibits androgen receptor-regulated transcription, which is similar to finasteride. It is worth mentioning, however, that this is not a human study but an in vitro study that focuses on the effects of CB-03-01 on dermal papilla cells. However, these results may be promising because CB-03-01 is a topical antiandrogen therapy that, in theory, is significantly less likely to cause systemic side effects such as finasteride.
CB-03-01 VS. Dutasteride
Dutasteride is a practical 5 α-reductase inhibitor, which can reduce the DHT of patients by up to 85% only one year after administration. Dutasteride has been proven more effective than finasteride in treating androgenic alopecia. Finasteride and dotasteride act by inhibiting 5 α-reductase, thus reducing DHT production. CB-03-01 works differently. Its effect is similar to that of DHT receptor inhibitors RU58841 and ketoconazole.
CB-03-01 VS. Minoxidil
The main similarity between CB-03-01 and minoxidil is that women can use it. According to the experiment results, women under the age of 30 who used 5% CB0301 twice a day showed significant improvement in the number of hair in the target area over a six-month interval.
Despite this similarity, the performance of minoxidil may be better than CB-03-01. How do we know? The experimental data in the literature support the fact that minoxidil produces more than 15-20 hairs per square centimeter. When we looked at participants' subjective assessments in the form of HGA scores, 7.5 percent of the twice-daily group had the best results, and about 62 percent of participants said they had experienced hair growth. Although this may seem small, it is worth mentioning that 50% of the participants in the placebo group (that is, carrier) also said they had experienced hair growth.
Factory Environment
1.Xi'an Sonwu Biotech Co., Ltd has its own factory,so it has adequate stock. Also,Xi'an Sonwu has clean and tidy producing department with advanced equipment. With the lead of Xi'an Sonwu, researchers are constantly developing new products to meet customer's need.
2.Xi'an Sonwu Biotech Co., Ltd has advanced test equipment and professional testers, which all show that Xi'an Sonwu aims to supply accurate and effective data and good service.
Certificates
Logistics Record
Except guaranteeing the product’s, the other most important thing is customers could receive the goods smoothly. So, Xi'an Sonwu Biotech Co., Ltd. supplies all kinds of courier according to different need.
Company Profile
Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012,and located in Hi-Tech industrial Zone, Xi'an city, Shannxi province, China. lt pays all attention on development, research and production of food additives, plant,extract,APl and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders,Nootropic,API,Muscle Building products, Plant Extract. Xi'an Sonwu sincerely believes that the premise of a great cooperation is best service and good quality. So, welcome your inquiry any time.
If you want to know CB-03-01 (Breezula) price, do not hestitate to consult Xi'an Sonwu Biotech Co., Ltd.
E-mail: sales@sonwu.com
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